,
who previously consulted on data mining algorithm integration with
Microsoft Research and SQL Server, and led data mining implementations for
a number of Microsoft divisions.

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For example , Apollo Data Technologies, through an alliance with Microsoft
SQL Server 2005, created for The Seattle Times Company a predictive model
to enable behavioral targeting and customer segmentation for direct
marketing to new and existing customers -- customers were segmented by news
and information consumption , as well as other data demographics.

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This includes not only barriers like technical ability, but also
barriers around total cost and user education, resulting in a low cost
solution that can be put into production much faster and with easier
maintenance than Predictive Analytic solutions built on other platforms. With IOP as the
infrastructure, SRI researchers will begin to integrate a user
interface, a model repository, new visualization tools, and various
biological databases into Pathway Logic. The support of NIGMS is helping to make this possible.com) is one of the
world's leading independent research and technology development
organizations.

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We turned to
Apollo's Predictive Analytic solution which combines tools, processes and
data mining expertise enabling us to quickly prepare, analyze and use the
critical data we needed.

Bayesian networks are used to show and calculate the effects of pieces of knowledge on each other.

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com) is the
first company delivering true predictive analytic solutions for key
vertical markets.
The NIGMS grant provides support for the mathematical modeling of
complex mammalian signaling and other biological networks, using SRI's
unique formal methods tools.

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"We used the SQL Server 2005 data mining platform to model for The Seattle
Times Company distinct news and information consumers within the regional
area based on behavior, attitudes about news, demographics and online
patterns and characteristics," said Jeff Kaplan, principal of Apollo Data
Technologies.

"Apollo has intimate knowledge of the workings of SQL Server 2005 Data
Mining, giving them an advantage in implementing solutions based on our
platform," said Jamie MacLennan, development lead, SQL Server Data Mining
for Microsoft Corp.

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About SRI International

Silicon Valley-based SRI International (www.

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When done properly, Predictive Analytics has emerged as a newly efficient
way to uncover consumer patterns , segments and behavior hidden within the
mass amounts of transactional, behavioral, call center and geo-demographic
data captured every day by businesses in industries such as retail and
consumer goods and media.

The additional breadth provided by the SQL Server 2005 platform allow
end -users to seamlessly perform tasks ranking from data preparation,
exploration, transformations, data mining modeling/prediction, then
publishing the analysis into insightful reports.

About Apollo Data Technologies

Founded in 2003, Apollo Data Technologies (www. Longer term,
these tools may prove useful in validating novel therapeutic targets
and predicting the side effects of experimental therapies.

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SQL Server 2005 Services


Previous internal methods for marrying market segmentation to marketing
databases had become outdated.

"It takes more than software to solve business problems. "This feature is one means by which
Pathway Logic offers the potential for researchers to model complex
cellular networks in a familiar or intuitive way.

They are strongly related to expert systems, but use probability theory to calculate those effects and can therefore easily deal with problems like uncertainty and missing data.

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Kaplan, Apollo is led by co-founder Paul Bradley Ph.'s who bring decades of distinguished
work in analytical CRM, deep expertise in building and designing data
mining applications, and the practical business know-how and experience in
applying the results.

SRI International Begins Second Phase of National Institute of General Medical Sciences Grant for Mathematical Modeling of Biological Systems; Formal Method To

reasoning inference

According to a recent study by IDC, Predictive
Analytic projects yielded a high median ROI of 145%.apollodatatech. The approach uses SRI's
patent-pending Pathway Logic(TM) pathway analysis software, based on
the Maude computer language (http://maude.com/), to model
biological entities and processes.

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PRESS RELEASE Apollo Data Technologies Announces Industry's First Predictive Analytic Solution

"The predictive model we deployed to their marketing database
enables the delivery of targeted marketing to different news and
information segments within the regional subscriber-base area, something
that no off-the-shelf statistical software package on the market today
could possibly do by itself.

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com) establishes
new depth by offering the latest, scalable algorithms from the research
community.

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----SRI
International, an independent, nonprofit research and development
institute , today announced continuation of an important grant from the
National Institute of General Medical Sciences (NIGMS, a unit of the
National Institutes of Health) to model complex mammalian signaling
networks based on signaling of the epidermal growth factor receptor
(EGFR).

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In the second phase of the project, SRI will increase the utility
and predictive capabilities of Pathway Logic by enhancing the ability
of researchers to interact with the models.

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apollodatatech.
Farness, Strategic Research Manager, Corporate Marketing, The Seattle Times
Company.D.
"Pathway Logic models of biological systems are unique in that
they are executable -- the models exist only when assembled on demand
from user-defined starting states," said Keith Laderoute, director of
SRI's Cancer Biology Program .

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The ultimate research goal of Pathway Logic is to create models of
large-scale signaling networks in defined cell types -- computational
models of mammalian cells defined in terms of their molecular
responses to specific environmental signals.

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In addition to conducting contract R+D, SRI
licenses its technologies, forms strategic partnerships and creates
spin-off companies.

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Additionally , the ability to plug in 3rd party algorithms
provides the flexibility to address vertical-specific data mining tasks.

Apollo's fees are based on a one time, per-engagement model(s) depending on
the complexity of the business requirements, while delivering an integrated
solution that combines:

-- Data Warehousing Expertise -- Cleaning and joining multiple data
sources including unstructured/structured
-- Data Mining Expertise -- Implementing a combination of algorithms,
processes and techniques to accurately apply advanced statistics to build
predictive models
-- Business Expertise -- Utilizing real-world business experience,
coupled with six sigma business practices to map both the data and
algorithms to the defined business objectives

Traditional statistical package licensing costs hundreds of thousands to
millions of dollars, with additional fees for internal resources, outside
consultants to build and deliver the analysis , as well as annual recurring
software maintenance fees.
In the project's first phase, SRI demonstrated a novel
computational approach to help researchers create, analyze, and test
models of complex EGFR signaling networks.

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Apollo Data Technologies
(www. An innovative solution employing the latest
predictive modeling method was sought that moved beyond what off-the-shelf
software packages might do. Apollo discovers hidden patterns and trends in data to
help business operate more effectively and efficiently.D.

daphne reasoning

"Microsoft and Apollo share the perspective on what it
takes to overcome the barriers to implementing predictive analytic
solutions."

SQL Server 2005 Analysis Services (www. This could
dramatically speed drug development and improve the safety of new
drugs -- major issues for pharmaceutical and biotechnology companies
today.

segmentation niedermayer

com) today announced the first true Predictive Analytic
solution that goes well beyond difficult-to-use, off-the-shelf statistical
software packages -- which have fallen short on delivering the analysis
marketers need -- and delivers highly effective target marketing, sales and
inventory forecasting, retention modeling and more.

All trademarks , trade names, service marks, and logos referenced herein
belong to their respective companies.

Business Editors/Health/Medical Writers/High-Tech Editors
BIOWIRE2K

MENLO PARK , Calif. Promoting the mathematical modeling of
biological systems is a primary goal of NIGMS, which intends to
disseminate such tools to biologists to help them understand the new
paradigm of systems biology and to design experiments. This phase will include
development of the Pathway Logic Assistant , an application of the
InterOperability Platform (IOP), a separately funded research project
to enable the formal methods tools written in the Maude language to
communicate and interact with each other. The
nonprofit research institute performs client-sponsored research and
development for government agencies, commercial businesses and
nonprofit foundations.

econometric approximate

Apollo provides solutions for all stages of data
analysis, including setting data collection strategies, text mining,
behavorial targeting, inventory forecasting, predictive analytics and more
for customers including Barnes & Noble, Microsoft Corporation, and The
Seattle Times Company.sri.

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I think more important, and what one would be
hard-pressed to find elsewhere, is how Apollo immediately understood what
our challenges were and partnered with us to solve them," said Janet K.sqlserverdatamining. It has a team of
world -renowned and award-winning Ph. SRI developed some of these tools
as part of a Web-based Pathway Logic viewer that allows multiple
queries of graphical models of EGFR biochemistry. Ultimately, we
intend to make our integrated and interactive online Pathway Logic
tools available to a wide community of biologists and biomedical
researchers.sri. Founded as Stanford Research Institute in 1946, SRI has
been meeting the strategic needs of clients for almost 60 years.

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