MetaDrug(TM) features maps, pathways and networks for human proteins
related to ADME/Tox; a database of small molecules with kinetic data for human
drug metabolizing enzymes , Proprietary algorithms for rule-based metabolite
prediction, highlighting of reactive metabolites , >40 QSAR models for ADME/Tox
properties, descriptors relevant to ADME parsers for importing data from all
major microarray platforms, SAGE, proteomics and metabolomics data; two
proprietary network building algorithms; flexible visualization and data
exchange tools.
MetaCore(TM) features a comprehensive set of maps, pathways and networks
for almost all known human proteins; parsers for importing data from all major
microarray platforms, SAGE, aCGH, RNAi proteomics and metabolomics data; seven
proprietary network building algorithms; flexible visualization and data
exchange tools.genego. These three Alias
products are development musts for the leading current-generation
console titles. An award-winning package,
MotionBuilder gives game title developers an advanced real-time
architecture, intelligent character controls, and revolutionary Story
Timeline performance environment within an intuitive animation
workflow.
Alias, the swirl logo, Can You Imagine and Maya are registered
trademarks and the Maya logo is a trademark of Alias Systems Corp.

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"PSP" is a trademark of
Sony Computer Entertainment Inc.

The use of render farms in the entertainment industry can be viewed as one early application of grid computing.

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Accelrys, Inc.

"Alias continues to deliver technology solutions that meet the
demands of game title development," said Geoff Foulds, global
industry manager for games at Alias. All Rights Reserved.

The reason for this is that advances in computer power are absorbed by increased computation in order to meet demands to achieve state-of-the-art image quality, while the hour-per-frame figure arises from the demands of production timescales.

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MetaDrug(TM) is designed for medicinal chemists, computational
chemists, bioanalytical , drug disposition and toxicology scientists and
enables prediction of metabolites and their likely toxicity in humans.

About Alias

As the world's leading innovator of 3D graphics technology , Alias
develops software for the film and video, games, web, interactive
media, industrial design , automotive, architecture and visualization
markets. Please visit the
Alias web site at http: //www.

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GeneGo Inc. Integrates Accelrys Accord Technology in MetaDrug(TM)

Eric Jamois, Director of Business Development at Accelrys.'s Tools and Middleware Program for
"PLAYSTATION(R)3" when it launches .

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For more information, please visit the company's Web site at
http://www.accelrys. Alias has headquarters in Toronto and a custom development
center in Santa Barbara with offices worldwide.

International contact numbers include: Northern
Europe, Middle East and Africa, +44 (0) 1494 441273; Germany, East +
Southeast Europe, 0049 89 31 70 20; France, Spain and Portugal, +33 1
44 92 81 60; Italy, 39 039 6340011; Japan and other parts of Asia
Pacific, 81 3 5797 3500 and Latin America , 770 393 1881. Alias Systems Corp.

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And because these features are combined with the foremost tools for
3D modeling, animation and rendering within a single,
production-proven workflow, Maya software has risen to become the
number one choice of top-rated game development facilities.

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, a leading provider
of databases and software for systems biology, announced today that they have
integrated Accelrys ' Accord technology in MetaDrug(TM), their Systems-ADME/Tox
and medicinal chemistry platform.
Accelrys technology and services are designed to meet the needs of today's
leading research organizations .

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JOSEPH, Mich., GeneGo Inc. "It took our
team several years to build tools and pathway content , proprietary algorithms
for metabolite prediction and ADME/Tox QSAR models. For more information about Accelrys, visit its website at
http://www. This will enable Alias to tailor
the roadmap for software products such as Maya(R), Alias
MotionBuilder(R) and Alias|HumanIK(R) middleware to the needs of
developers working on SCEI's "PLAYSTATION(R)3".

A render farm is a computer cluster to render computer generated imagery (CGI), typically for film and television visual effects.

Source: Wikipedia

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The rendering of images is a highly parallelizable activity, as each frame can be calculated independently of the others, with the main communication between processors being the upload of the initial source material, such as models and textures, and the download of the finished images.

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"Integrating Accelrys' Accord technology with GeneGo's MetaDrug, is
another example of how Accelrys is looking to expand access to best-of-breed
technologies to scientists in the Pharmaceutical and Biotech sector ,"
commented Dr."

About GeneGo
GeneGo is a Michigan-based company developing systems biology technology
for life science research.

Alias to Join the Sony Computer Entertainment Inc.'s Tools + Middleware Program for 'PLAYSTATION'R'3'

"In the future, game software
will require more and better quality graphics than ever dreamed of. The software provides developers with flexible character
definition templates and animation reusability -- resulting in
improved character animation quality and increased productivity.

optimize mtp

GeneGo's first product, MetaCore(TM), assists pharmaceutical scientists in the
areas of target selection and validation, identification of biomarkers for
disease states and toxicology. GeneGo's second product, MetaDrug(TM) is a
pioneering Systems-ADME/Tox platform which combines software for predicting
metabolites and over 40 ADME/Tox properties with visualization and analysis of
toxicogenomics and metabolomics data. is a leading provider of software for computation ,
simulation, and the management and mining of scientific data used by
biologists, chemists and materials scientists, including nanotechnology
researchers for product design as well as drug discovery and development.

throughput demands

Alias MotionBuilder is the world's leading 3D character
performance and animation system.com or call 1-800-447-2542 in
North America.

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MotionBuilder is highly extensible through its OpenReality
SDK and Python scripting capabilities.

Alias offers services for game developers ranging from
self-paced, online learning materials and custom training for artists
and programmers , to custom engineering of Alias tools and the
extension and refinement of development pipelines according to
customers' unique production needs.

The software is typically a client-server package that facilitates communication between the processors and the queue manager, although some queues have no central manager .

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Tekken is a trademark of Namco Ltd.

As a rule of thumb, CG images take roughly an hour per frame to render.

Some common features of a queue managers are: re-prioritization of the queue, management of software licenses, and algorithms to best optimize throughput based on various types of hardware in the farm.

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MetaDrug(TM) can be used as a stand
alone product or together with MetaCore(TM), GeneGo 's flagship analytical
platform."

About Alias' Games Solutions

Maximizing productivity is a defining requirement of game
pipelines, and 3D tool extensibility is a key factor in achieving
this. in
the United States and/or other countries. "PlayStation" is a registered
trademark of Sony Computer Entertainment Inc.

demands lightwave

We can now apply the
Accord tools for molecule visualization and database searching capabilities
within MetaDrug(TM).

MetaCore(TM), MetaBase(TM) and MetaDrug(TM) are trademarks of GeneGo,
Inc. The company is headquartered in San Diego,
California .

(C) Copyright 2005.

queues timescales

"Combining the power of the Accord Chemistry engine with MetaDrug's algorithms
will ultimately help enhance the data visualization and database searching
capabilities of MetaDrug . The Company's original computational platform
MetaCore allows an integration and analysis of different kinds of high
throughput experimental data (mRNA expression, proteomics, metabolites,
phenotypic data etc.com.

About Accelrys, Inc. in the
United States and/or other countries. Alias , 210 King Street East,
Toronto, Ontario, Canada, M5A 1J7, Tel: 416-362-9181, Fax:
416-369-6140 .

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News Editors

LOS ANGELES----E3

Maya, Alias MotionBuilder and Alias|HumanIK middleware to support
development of "PLAYSTATION(R)3" games titles

Alias announced today its intention to join the Sony Computer
Entertainment Inc.
With its decades-long history of providing award -winning software to
the film and game development industries, Alias is delivering
innovative, production-proven technology and service solutions that
developers need.

spite demands

Sean Ekins, Vice President , Computational Biology at GeneGo. The Maya patented Dependency Graph and integrated API and
scripting language make it the most extensible 3D package available. All other trademarks mentioned herein are
the property of their respective owners.

The amount of time it takes to render an image has remained roughly constant over two decades, in spite of huge improvements in computer processing power.

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To manage large farms, one must introduce a queue manager that will facilitate automatic distribution of processes to the many processors.

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ST."
"We are thrilled to be working with Accelrys and excited about the
capabilities of our combined software for the field of Systems-ADME/Tox," said
Dr.) and relevant active chemistry (metabolites, drugs, other
xenobiotics) within the framework of biological pathways and networks.com/. The software natively supports FBX(R): a free,
platform-independent, 3D authoring and interchange format from Alias
that enables MotionBuilder to work seamlessly with other 3D software
packages.

Game Title Development for "PlayStation(R)2" and "PSP(TM)" Relies
on Alias Software

Maya, Alias MotionBuilder and Alias|HumanIK software are the
development tools of choice for such award-winning and best selling
"PlayStation(R)2" and "PSP(TM)" titles as MVP Baseball 2005 (EAC),
Tekken(TM) 5 (Namco), and Untold Legends(TM): Brotherhood of the
Blade(TM) (SoE).

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Alias|HumanIK middleware is a licensed development library that
allows game title developers to integrate an intelligent full-body,
or by-body-part, character IK system that can be used within a
runtime game engine in order to process biped and quadruped character
animation. Alias looks forward to supporting game title
developers of "PLAYSTATION(R)3" titles in the future.alias. MotionBuilder , HumanIK and
FBX are registered trademarks of Systemes Alias Quebec Inc.
Untold Legends and Brotherhood of the Blade are trademarks of Sony
Online Entertainment Inc.