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Leerink, CEO and Chairman of Leerink Swann. Through its consulting affiliate, MEDACorp,
Leerink Swann & Company provides biomedical-consulting services to Life
Sciences companies and to the institutional investment community.

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The Medicines Company is headquartered in Parsippany, New
Jersey.

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About The Medicines Company

The Medicines Company (NASDAQ: MDCO) develops products that improve acute
hospital care, and it markets Angiomax (bivalirudin) for injection, an
anticoagulant approved for use in patients undergoing coronary angioplasty
procedures.

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PRESS RELEASE Leerink Swann Inaugural Health Care Conference a Success

Leerink Swann & Company is a member NASD/SIPC.

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The Conference attracted more than 350
attendees.

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"We are very pleased with the success of our Inaugural Health Care
Conference," said Jeffrey A. "Having some
of the most recognized experts in biotechnology gathered together for this
Inaugural Conference from MEDACorp's consultant base to respond to breaking
news concerning pharmaceutical companies demonstrates the value-added in
the information we are able to provide to our clients," added William
Tanner, Leerink Swann's Director of Research.

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The Inaugural Leerink Swann/MEDACorp Health Care
Conference was held on March 1, 2005, at the New York Plaza. MEDACorp
includes thousands of biomedical professionals and practicing physicians.

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MEDACorp
includes thousands of biomedical professionals and practicing physicians.

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"The Conference provided our clients with a day full of valuable
information and the opportunity to interact with biomedical professionals
and health care company managements," continued Mr.

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About Leerink Swann & Company

Leerink Swann & Company is an investment banking firm that provides
healthcare equity research , corporate finance, and asset management
services for institutional and high-net-worth clients.

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Schwartz initiated coverage of The Medicines Company with an
Outperform rating.

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About Leerink Swann & Company

Leerink Swann & Company is an investment banking firm that provides
healthcare equity research, corporate finance, and asset management
services for institutional and high-net-worth clients .
This morning, Senior Biotechnology Analyst
Joseph P.

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Leerink.

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The Conference
showcased panels of doctors from the MEDACorp network combined with
presentations by more than 40 companies , providing cutting-edge insights
into the health care industry. Leerink Swann &
Company was voted the Best Firm in Biotechnology, Medical Supplies and
Devices, Pharmaceuticals/Major and Pharmaceuticals /Specialty in the
December 2004 Institutional Investor poll ranking the best boutique and
regional firms by sector. Leerink Swann &
Company was voted the Best Firm in Biotechnology, Medical Supplies and
Devices, Pharmaceuticals/Major and Pharmaceuticals/Specialty in the
December 2004 Institutional Investor poll ranking the best boutique and
regional firms by sector.

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Leerink Swann & Company is a member NASD/SIPC.

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Through its consulting affiliate, MEDACorp,
Leerink Swann & Company provides biomedical-consulting services to Life
Sciences companies and to the institutional investment community .

PRESS RELEASE Leerink Swann +amp; Company Initiates Coverage of The Medicines Company (NASDAQ: MDCO )

His investment rating is based on his belief that The
Medicines Company (NASDAQ: MDCO) will expand the sales of its Angiomax
drug beyond its use in coronary angioplasty.

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