Hon . In
the United States, these mutations are detected in approximately 1 in 25 non-
Jewish Caucasians of European ancestry and Ashkenazi Jews and at lower
frequencies in Americans of African, Asian or Hispanic ethnicity.

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Ukraine is Part of Europe

org


benveniste italic

"This agreement with CHMCA will result in innovative quality
control products designed to increase the accuracy and reliability of cystic
fibrosis testing.


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CF is a hereditary disease associated with mutations in the CFTR gene that
results in chronic pulmonary disease and other clinical manifestations.

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yes-ukraine .

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Second conclusion: concerning the present official position of the
EU, which agreed to open negotiations with Turkey but is still against
the possible accession of Ukraine, Europeans:

are only 9% to consider that it is right


Ukraine (43% with both countries, 14% only with Ukraine )

Third conclusion: regarding the arguments about Ukraine, we can
see that:

-- Europeans in favour of the accession of Ukraine explain their
position because "Ukraine is part of Europe" (39%) and because "this
accession would strengthen democracy in Ukraine" (36%)

-- Europeans against the accession of Ukraine explain their
position because "Ukraine will have to strive harder in terms of
democracy" (40%) and because "Ukraine is a poor country, its accession
would be a handicap for the EU" (36%) but also because "I'm against
the enlargement of the EU" (31%).

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This survey has been conducted in the six biggest countries of the
EU (Germany, France, UK, Italy, Spain and Poland, which represent 75%
of the EU population) from February 24th to March 8th with national
representative samples of the population aged 18 and over in all
countries (1 000 interviews in each country). AcroMetrix maintains this
leadership role by consistently developing innovative proficiency panels,
standards, external run controls, and validation kits for molecular testing in
blood screening and clinical diagnostic laboratories.com.

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For more information on
AcroMetrix please visit the company web site at http://www.

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"Our scientists
have worked extremely hard to develop this new technology , which will assist
physicians by enhancing the accuracy of test results.

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italic anachronism

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Ukraine was the first to be quoted in four European
countries (Poland with 77% in favour, Italy with 62%, Spain with 60%,
France with 58%) and second in two other countries (UK with 49%,
Germany with 41%). Although
more than 1000 CF mutations have been identified, a relatively small number of
these, approximately 25 mutations, account for the majority of CF cases in the
United States.
"Cystic fibrosis screening is an important step in the fight to lessen the
impact of hereditary diseases in the United States," said Michael J.

benveniste sephardic

Stephen Byers

Victor Pinchuk

Marek Siwiec

Stephane Fouks

Alexander Rahr

Jean-Pierre Saltiel

The full results of the survey and some more information about YES
are available on the website: www.

AcroMetrix and Children's Hospital Medical Center of Akron Sign Agreement on Quality Control Products for Cystic Fibrosis Testing

DALLAS , AcroMetrix Corporation announced today
that it has signed an exclusive agreement with Children 's Hospital Medical
Center of Akron (CHMCA) to develop and commercialize quality control products
for cystic fibrosis (CF) testing using CHMCA's new proprietary technology.

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These state-of-the -art controls will have a major impact on the way that CF
test results are interpreted.acrometrix .

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This screening for high prevalence mutations using molecular diagnostic test
methods identifies carrier couples with a one in four risk for affected
offspring with each pregnancy, and offers them genetic counseling and various
reproductive options.

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YES is going now to publicise this survey widely and to organize a
real European debate about Ukraine and the EU all along the year 2005,
by:

-- organizing four conferences: in Brussels on the 24th of May
with President Kwasnievski , in Yalta from the 21st to the 24th of
July, in London and in Berlin in the fall."
"We are thrilled to be collaborating with AcroMetrix to leverage our
research on advanced disease screening tools," said Deborah Bonzak, Vice
President of Ancillary Services at Akron children's Hospital."

About AcroMetrix
AcroMetrix, with facilities in Benicia, CA and Alkmaar, Netherlands ,
provides a comprehensive line of molecular diagnostic quality control products
that assist laboratories in meeting current government regulations and
recommendations regarding quality assurance.

iberian sephardim



Business Editors

KIEV, Ukraine----YES (Yalta
European Strategy), an international network established to open
Ukraine to the rest of the world and to support Ukraine's EU
membership, has ordered a survey to TNS Sofres about the perception of
Ukraine in the EU.
The American College of Medical Genetics (ACMG) and the American College
of Obstetricians and Gynecologists (ACOG), in conjunction with the National
Human Genome Research Institute (NHGRI), have issued recommendations and
guidelines for CF carrier testing in a population-based screening program. Eck, CEO
of AcroMetrix.

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benveniste seth



First conclusion: concerning the future, supposing that these
countries were to apply to join the EU and met all the conditions for
accession, Ukraine is the country for which Europeans are the most in
favour of accession (55% in favour, 31% in disfavour) before Russia
(with respectively 50% and 38%), Turkey (45% and 43%) and Morocco (35%
and 50%). Because of the technical complexity of these tests,
ACMG, ACOG and the NHGRI have also recommended that laboratories conducting CF
carrier screening comply with stringent quality assurance guidelines.

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-- carrying out three different studies: "perception of European
business community about Ukraine and recommendations to foster
economic development," "perception of European political leaders about
Ukraine and recommendations to bring the country closer to the
European Union," "benchmark on membership strategy: what can we learn
from Turkey and Poland?"

YES Executive Board

Rt.

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seth sefarad

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