"A woman's medical history needs to be the first determining factor when
selecting a birth control method, but side effects like breakthrough bleeding
that can affect proper use and satisfaction also must be considered," said Dr.

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kaloramainformation. For more
information, contact Steven Heffner at 212-807-2634 or
sheffner@kaloramainformation.203 or ifrukhtbeyn@marketresearch .

* Almost three-quarters (72%) of women surveyed agreed that breakthrough
bleeding or spotting would be inconvenient and could have a negative
impact on a woman's life. A healthcare professional can help women decide among
all the options available and choose the best pill for the patient's unique
needs and preferences.com

Important Safety Information
Oral contraceptives are not for everybody.orthowomenshealth.

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The new study, Markets in Human Reproductive Medicine: Contraception and
Infertility Management, forecasts steady growth in the hormonal contraceptive
market . "However, there are products on the horizon that may
radically change the dynamic-products that can combine contraceptive and
antimicrobial activity to combat disease transmission, including HIV .

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* More than six in ten (62%) women surveyed agreed that breakthrough
bleeding or spotting could cause a woman to feel embarrassed or self-
conscious.

ORTHO TRI -CYCLEN LO (norgestimate/ethinyl estradiol)
ORTHO TRI-CYCLEN(R) LO (norgestimate/ethinyl estradiol ) is the only birth
control pill with a combination of 25 micrograms of ethinyl estradiol and the
progestin, norgestimate.

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"
The report, which also examines the infertility management sector ,
analyzes usage worldwide, reviews the product pipeline, and provides key
market data including size, growth, competitive market share.com/pub/1077871.MarketResearch.

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com
301. In fact, in one study, women
who experience bleeding irregularities in their first three months on a birth
control pill are almost twice as likely to stop taking it as those who do not
experience these symptoms.

Hutcherson.com.

About Ortho Women's Health
For more than 73 years, Ortho Women's Health , makers of
ORTHO TRI-CYCLEN LO and ORTHO EVRA(R) (norelgestromin/ethinyl estradiol
transdermal system), a division of Ortho-McNeil Pharmaceutical, Inc. Ortho Women's Health, a trusted partner of
healthcare professionals, is committed to bringing women the most advanced
options in contraception .

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NEW YORK, The world market for hormonal
contraceptive products will surpass the $6 billion mark in 2005, according to
a new report released today from Kalorama Information.com.

* Nearly three-quarters (73%) of women surveyed who had experienced
breakthrough bleeding agreed that it would disrupt a woman's sex life."
It is important for women to understand that the amount and type of
estrogen and progestin in birth control pills plays a role in the benefits and
side effects associated with different pill types.
ORTHO TRI-CYCLEN LO, which was approved by the U. For more information, visit
http://www.com.com

(1) A nationwide telephone omnibus survey of 1,015 American women 18 years
of age and older regarding their experience with the birth control pill and
perceptions of breakthrough bleeding.

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About Kalorama Information
Kalorama Information, an imprint of MarketResearch.

About MarketResearch.J.

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Worldwide Hormonal Contraceptive Market to Surpass $6 Billion in 2005

However, price pressures and reimbursement issues have limited the
penetration of newer methods of hormonal birth control.html. For more information , contact Irina Frukhtbeyn at 301-468-3650
x.
Please see full U.thepill.

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com, supplies the
latest in independent market research for the life sciences.

Contact:
Irina Frukhtbeyn
MarketResearch.com

"However, according to
research, as well as my own experience with my patients, breakthrough bleeding
is the side effect that is more likely to cause women to stop taking or switch
their pill. Cigarette smoking increases the risk
of serious cardiovascular side effects, especially if you're over 35.

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"Given the success of hormonal contraception, it makes sense that recent
research has focused on hormonal methods-particularly on the development of
new delivery systems and extended dosing to increase product differentiation
and gain a competitive edge," notes Steven Heffner, acquisitions editor at
Kalorama Information.
Priced at $3,500 , it can be purchased directly from Kalorama Information
by clicking http://www.468.

Survey Insights
Previous research has shown that breakthrough bleeding is one of the
leading causes for discontinued use of the Pill. Food and Drug
Administration in 2002, contains a balance of estrogen and the progestin
called norgestimate.

Information about birth control is in Health:Reproductive Health:Birth Control.

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com
MarketResearch. This new survey offers further insights about
breakthrough bleeding and how the condition may affect women's everyday
lifestyle:

* Sixty percent of women surveyed agreed that breakthrough bleeding may
cause a woman to feel unsure about the effectiveness of the Pill.

"When evaluating whether or not to take birth control pills , too many
women focus on the long-standing myth of perceived weight gain," said Dr. It is important to ensure that women take
the Pill consistently, every day, at roughly the same time every day, as not
doing so can lead to onset of unscheduled spotting. This low-dose pill helps prevent pregnancy while
providing excellent cycle control and a low incidence of nuisance side effects
such as breakthrough bleeding. Some women
should not use the Pill, including women who have blood clots, certain
cancers , a history of heart attack or stroke, as well as those who are or may
be pregnant. A Computer Assisted Telephone Interviewing (CATI) facility and
Random Digit Dialing (RDD) technology were used. The profile of norgestimate is associated with low
rates of nuisance side effects, such as weight gain and acne.

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"Certain pills, such as ORTHO TRI-CYCLEN(R) LO
(norgestimate/ethinyl estradiol), for example , have a low occurrence of
breakthrough bleeding and spotting.S. In a clinical study, fewer than one in five
ORTHO TRI-CYCLEN LO users reported these potentially embarrassing side
effects in their first month on the Pill.

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In the United States, for example, more than 35% of women under age
30 use hormonal contraception as the method of choice-more than 50% more than
condoms, the second most popular method."

What is Breakthrough Bleeding?
Breakthrough bleeding is defined as the bleeding that a woman on the Pill
experiences at an unexpected time.thepill. By delivering superior and innovative products,
services, and education, Ortho Women's Health helps empower women to make the
right choice for themselves and their bodies.

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It is also
available at http://www.com . Breakthrough Bleeding Between Periods Impacts Pill Use

RARITAN, N.
"There are many reasons that women bleed or spot mid-cycle while starting
out on a new birth control pill -- most often it is the body adjusting to the
Pill," says Dr. Serious risks, which
can be life threatening, include blood clots, stroke, and heart attacks, and
are increased if you smoke cigarettes .

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New Survey Suggests Overlooked Side Effect Causes Many Women to Stop or Switch Birth Control Pills

ORTHO TRI-CYCLEN LO is indicated for the prevention of pregnancy in women who
elect to use oral contraceptives as a method of contraception.

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Hutcherson.

153 substantially

Insurers report that
products such as the patch can cost them almost ten times as much as
traditional birth control pills, and as a result , some health insurers
actively steer women toward specific forms of contraceptives.
Usage trends suggest that hormonal contraceptives, which now enjoy about a
15% market share worldwide, will continue to find more users in the coming
years.com. Most commonly, it occurs in the first
three months on a new pill, and will often cease incidence once the body
adjusts to the hormonal dosage., has
listened to women's needs and responded with products and information to help
them live healthier lives.

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com, or visit http://www.
Hilda Hutcherson, OB/GYN and Co-Director of the New York Center for Women's
Sexual Health, Columbia Presbyterian Medical Center. She adds that breakthrough bleeding doesn't
lessen the efficacy of the Pill, but most women are bothered by it and often
want a "quick fix" by switching pills or to other less-effective birth control
methods .

What Women Can Do: Choose a Pill that Fits
The survey results demonstrate that breakthrough bleeding is a definite
concern among women who are either taking or considering the Pill. The margin of error for the total sample of 1,015 is +/-3.

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3650 x203
ifrukhtbeyn@marketresearch. However , when considering the Pill at the outset, women may
overlook breakthrough bleeding as one of the side effects that may occur.

Please see full U.

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Oral and injectable
formulation products will continue to dominate the sector, as alternative
delivery methods such as patches and implants battle for consumer and
reimbursement acceptance.com is the leading provider of global market intelligence
products and services with over 91,000 research publications from 350 research
publishers., suggests breakthrough bleeding (defined as the bleeding
that a woman on the Pill experiences at an unexpected time) is a culprit that
should not be ignored. According to the survey, 63% of women who experienced
breakthrough bleeding discontinued or changed their birth control pill
prescription. In order
to choose a pill that suits their lifestyle and addresses these concerns,
women need to carefully evaluate their options and consider taking a low-dose
birth control pill that offers a low incidence of nuisance side effects while
maintaining efficacy.

About the Survey
StrategyOne conducted a nationwide telephone omnibus survey, sponsored by
Ortho Women's Health, of 1,015 American women 18 years of age and older
regarding their experience with the birth control pill and perceptions of
breakthrough bleeding. The data were analyzed by
StrategyOne.1% at
the 95% level of confidence . Of those surveyed, 61% either currently
use or have used the Pill.

The abortion issue is covered in Society:Issues:Abortion.

The sub-category 'Organizations' lists institutional organizations ' sites.

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Further, 55% of all women surveyed, regardless of personal experience
with this side effect, agreed with this statement.
The interviews were conducted via telephone from October 28, 2004 to
November 1, 2004 utilizing the field services of ORC (Opinion Research
Corporation ).

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To learn more about ORTHO TRI-CYCLEN LO, visit http://www. Most side effects of the Pill
are not serious and those that are, occur infrequently. Prescribing Information for ORTHO TRI-CYCLEN LO
enclosed or at http://www.S Prescribing Information enclosed or at
http://www.

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Women
who use oral contraceptives are strongly advised not to smoke. The Pill does not protect against HIV or sexually transmitted
diseases.S.

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KaloramaInformation., Many women consider weight gain to
be the top reason women stop or change their birth control pills, yet a
survey(1) released today by Ortho Women's Health, a unit of Ortho-McNeil
Pharmaceutical Inc.thepill.