("Option Care" or the "Company") today announced that the
universal shelf registration statement on Form S-3 filed on January
24, 2005 with the Securities and Exchange Commission was declared
effective on February 4, 2005.
This press release does not constitute an offer to sell or the
solicitation of an offer to buy securities nor shall there be any sale
of these securities in any state or jurisdiction in which such offer,
solicitation or sale would be unlawful prior to registration or
qualification under the securities laws of such state or jurisdiction., University Physicians at Stony
Brook (UPSB), the coordinating entity for a faculty practice of 500 physicians
in Stony Brook, New York, is implementing PatientKeeper ePrescription(TM)
(Powered by DrFirst ) on behalf of its Practices as part of a mobile healthcare
initiative to improve quality of care and patient safety. For more information, visit
http://www.

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Hau, PatientKeeper, shau@patientkeeper .

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Forward-Looking Statements

This press release contains certain forward-looking statements
within the meaning of Section 27A of the Securities Act of 1933, as
amended, and Section 21E of the Securities Exchange Act of 1934, as
amended, which are intended to be covered by the safe harbors created
thereby., Ph.

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The universal
shelf registration statement on Form S-3 also registers 2 ,000,000
shares of the Company's common stock beneficially held by Dr. Forward looking statements can be identified by the use of
terms such as "anticipates," "expects," "believes" and other words
having a similar meaning.
In addition, the software warns doctors of possible allergic or drug -drug
interactions.

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Option Care Announces Shelf Registration Statement Declared Effective by the Securities and Exchange Commission

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cohen@stonybrook.

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The ability for a physician to electronically submit a prescription directly
to a pharmacy is also endorsed by National Association of Chain Drug Stores
(NACDS) as a technology that will improve the safety and efficiency of drug
prescribing as well as the quality of medication decisions.

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The company's
services and pharmaceuticals are provided nationally through its local
and regional pharmacies.edu,
(631) 444-2055
Amanda Sina, Schwartz Communications, patientkeeper@schwartz-pr.

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ePrescribing has been identified as an IT investment that improves the
quality of patient care and reduces medication errors, according to the
federal government's healthcare IT coordinator, David J.

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Business Editors/Healthcare Editors
BIOWIRE2K

BUFFALO GROVE, Ill.

About Option Care

Option Care provides various home infusion therapies and specialty
injectable pharmaceuticals to patients at home and other alternate
sites such as infusion suites and physician's offices. Investors are cautioned that all
forward-looking statements involve risks and uncertainty. Instead of jotting information on cards, doctors
use the system to simply check off customizable diagnosis codes and services
right on their handheld devices .

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Such
forward-looking information involves important risks and uncertainties
that could significantly affect anticipated results in the future and,
accordingly, such results may differ from those expressed in any
forward-looking statements made by us, or on our behalf.

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PatientKeeper Charge Capture Client Expands with ePrescription Application

STONY BROOK, N.

About PatientKeeper
PatientKeeper(R), Inc.com, (617) 987-0304
Ellen Dank Cohen, CPMP, SUNY @ Stony Brook, ellen .

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These risks
and uncertainties include, but are not limited to, uncertainties
affecting our businesses and our franchisees relating to acquisitions
and divestitures (including continuing obligations with respect to
completed transactions), sales and renewals of franchises, government
and regulatory policies (including federal, state and local efforts to
reform the delivery of and payment for healthcare services), general
economic conditions (including economic conditions affecting the
healthcare industry in particular), the pricing and availability of
equipment and services, technological developments and changes in the
competitive environment in which we operate.
Further Information on Option Care Can Be Found at:
www. ePrescription creates, modifies, saves, prints, and faxes or
electronically transfers prescriptions directly and securely to the pharmacy.

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optioncare.

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UPSB doctors are
already using PatientKeeper Charge Capture(TM) to streamline the charge
capture and billing processes.D.

"ePrescription should make prescription writing
easier for doctors while reducing chances of error caused by misread written
instructions.

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Y. Brailer, M.

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Electronic charge capture is a major advance
over a paper system in recording the services and procedures the physicians
provide to their patients ."
Doctors will use the mobile software platform for wireless access to the
hospital's patient information system.patientkeeper.

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These statements are
based upon assumptions and, although the Company believes that the
assumptions underlying the forward-looking statements contained herein
are reasonable , there can be no assurance that the forward-looking
statements included in this press release will prove to be accurate.

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The universal registration statement on
Form S-3 allows the Company from time to time to sell up to an
aggregate of $70 million equity and/or debt securities. ePrescription provides physicians with
an electronic prescription tool at the point of care, managing the entire
prescription process from start to finish.
Charge Capture automates the billing process that typically relies on
individual billing cards.com or call 617-987-0300.

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University Physicians at Stony Brook Improving Quality of Patient Care and Safety with ePrescription

"Physicians today have to look at the most efficient ways to practice and
using new technology can be an important part of that," said Ellen Dank Cohen,
executive director of UPSB. Physicians can enter prescription
orders, check patients' medication histories, and review formularies from
anywhere, at any time, including in the hospital, in the office, and points in
between. An accurate record of services provided is
recorded and added to the patient record. Charge Capture provides two layers
of rule-checking, ensuring complete , accurate bills; support for both
inpatient and outpatient workflows; support for PDAs, tablets, and desktops;
browser-based reporting and management tools for the billing staff; and tight
integration with existing billing systems.

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The
PatientKeeper Platform(TM) easily integrates with existing information
systems. PatientKeeper and its partners have created a portfolio of
applications that allow doctors to interactively manage patient information,
view clinical results, enter charges, dictate notes , write prescriptions,
access medical references, and more.com,
(781) 684-6269

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com

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----Option Care,
Inc. John N.
Kapoor, the Chairman of the Board of Option Care, for possible future
sale from time to time.
The 500 providers of University Physicians practice in 18 separate
specialty groups that provide a range of medical services from primary care to
the most advanced specialty care for patients of all ages. provides healthcare professionals with mobile
computing solutions that deliver clinical and financial benefits.

Contact:
Stephen S.