That is the
gap between high-bandwidth, high-margin Ethernet over fiber services and
low-bandwidth DS1 or Ethernet over DS1 HDSL-based solutions.

sli declassified

Additional information about Lexicon is available through its corporate
website , http://www.
The Aktino AK4000 product family, an Ethernet in the First Mile (EFM)
solution , is the industry's first cost-effective and operationally feasible
business broadband solution that bridges a critical service gap.com

Aktino, MIMO on Copper and MIMO on DMT are trademarks of Aktino, Inc.

skeptic limb

About Lexicon Genetics
Lexicon Genetics is a biopharmaceutical company focused on the discovery
and development of breakthrough treatments for human disease.com .
The AK4000 product family is designed to extend Metro Ethernet services to
the profitable and underserved small and medium-sized enterprise (SME) market
segment.

tentative eel

Sands, president and chief executive officer , and Julia P.lexicon-genetics. Information identifying such important factors is contained under
"Factors Affecting Forward-Looking Statements" and "Business - Risk Factors"
in Lexicon's annual report on Form 10-K for the year ended December 31, 2004,
as filed with the Securities and Exchange Commission . Since the platform is built with the most widely deployed DSL
technology, DMT, its services do not interfere with existing DMT-based ADSL,
ADSL2, VDSL and future VDSL2 services.

limb physiological

By applying
MIMO techniques to a DMT-based platform, it enables the AK4000 to mitigate
cross-talk interference and transport greater Ethernet bandwidth over longer
distances on fewer pairs than any other currently available technology.

altering crystalinks

Lexicon Genetics to Report Fourth Quarter and Full Year 2005 Financial Results on February 22 2006

Conference Call and Webcast to Follow

THE WOODLANDS , Texas, Lexicon Genetics
Incorporated (Nasdaq: LEXG) will release its fourth quarter and year end 2005
financial results on Wednesday, February 22, 2006 before the financial markets
open. The AK4000
family is GA (generally available) and shipping to service providers
throughout North America .

telepathy lucid

"

About Aktino
Aktino designs and delivers innovative carrier-class long reach broadband
over copper solutions that enable service providers to offer revenue
generating business-class broadband services over existing copper loops.

parapsychology interference

The Company has advanced knockout-
validated targets into drug discovery programs in six therapeutic areas:
diabetes and obesity, cardiovascular disease , psychiatric and neurological
disorders, cancer, immune system disorders and ophthalmic disease.

The AK4000 meets all T1.
"With the growing demand for Ethernet from business customers , service
providers have been actively searching for a solution to cost-effectively
bridge the gap between Ethernet on fiber services and Ethernet over legacy DS1
services," said Bruce Kimble , president and CEO of Aktino. That significantly
increases the size of a telco's serviceable footprint and its potential
market.

limb skeptic

The pass code for all callers
is 7195604.
"There is clearly a demand for flexible Ethernet services from
enterprises."
The AK4000 product family is built with the same core technology -- MIMO
on DMT -- as Aktino's recently announced AK3000 product family .

speculations telepathy

Lexicon will hold a conference call to discuss its results at
11:00 a. Eastern Time on February 22, 2006. Now the challenge is to offer ubiquitous
Ethernet services to all customers and locations , whether served by fiber or
copper," commented Ron Westfall, broadband infrastructure principal analyst
for Current Analysis. "The Aktino AK4000
Ethernet over Copper solution bridges this gap.

electromagnetic psychokinesis

Arthur T. Lexicon is
systematically discovering the physiological and behavioral functions of genes
to identify potential points of therapeutic intervention, or drug targets.

psychokinesis limb

Lexicon makes these discoveries using its proprietary gene knockout technology
to model the physiological effects that could be expected from prospective
drugs directed against novel targets. Lexicon undertakes no
obligation to update or revise any such forward-looking statements, whether as
a result of new information, future events or otherwise. "Aktino's MIMO on DMT technology enables Metro Ethernet
service providers to provide a compelling value proposition to copper served
customers -- who are currently limited to multiples of 1.

tentative apparently

5 Mbps -- with an
upgrade option to a 10 Mbps or higher offering.

apparently tentative

These
forward-looking statements are based on management's current assumptions and
expectations and involve risks, uncertainties and other important factors,
specifically including those relating to Lexicon's ability to successfully
conduct preclinical development of its drug candidates and advance such
candidates into clinical development, achieve its operational objectives,
obtain patent protection for its discoveries and establish strategic
alliances, as well as those relating to manufacturing, the regulatory process ,
intellectual property rights, and the therapeutic or commercial value of its
drug candidates , that may cause Lexicon's actual results to be materially
different from any future results expressed or implied by such forward-looking
statements. To date, telcos have responded with several Metro Ethernet
offerings for large enterprises.

Psychokinesis is the altering of physical events and processes through the power of the mind.

psychokinesis electromagnetic

Aktino's 'MIMO on DMT' Technology Powers New Platform for Ubiquitous Ethernet

tampering speculations

lexicon-genetics. Lexicon is
working both independently and through strategic collaborations and alliances
to accelerate the development and commercialization of its discoveries ., Aktino, the first company to
implement MIMO (Multiple Input Multiple Output) techniques on DMT (Discrete
Multi Tone)-based copper access platforms, today publicly announced its AK4000
product family. However, this has been mostly limited to
locations that have access to fiber. Since the AK4000 delivers two
to five times the bandwidth per pair compared to legacy solutions, it needs
fewer pairs to each location to deliver services. Founded in 2003 and headquartered
in Irvine, California , Aktino is currently shipping products to service
providers throughout the world.

eel influencing

eel parapsychology

Gregory, executive vice president of corporate development and chief financial
officer, will host the conference call .com to listen to
a live webcast of the call.SHDSL. For more information, visit http://www.

parapsychology tampering

The platforms can transport a symmetrical 10 Mbps Ethernet service
on four copper pairs or a symmetrical 25 Mbps Ethernet service on eight pairs
-- with a binder full of disturbers -- throughout the CSA (12,000 feet over
24-gauge wire).

psychokinesis crystalinks

Dr. Investors can access http://www.aktino.

speculations eel

It can be seamlessly integrated into existing
service provider copper access networks and future Fiber to the Node network
architectures.

sli influencing

m. The AK4000 enables true 10 to 25 Mbps business-class Ethernet
services and guarantees ubiquity of those services over the entire Carrier
Serving Area (CSA - 12,000 feet over 24-gauge wire).417 spectral requirements, even at high bandwidth
levels and extended distances .

altering interference

They will review Lexicon's operating
highlights and financial results for the year ended December 31, 2005 and will
discuss the company's guidance for 2006. The webcast will be archived and available for
review through February 27, 2006. The platform is environmentally hardened for any deployment
scenario, and can be line powered on the same pairs that transport the
Ethernet traffic. The AK4000 is designed to complement
and co-exist with service providers' ever-increasing DMT investments in the
local loop, unlike systems that use echo cancelled approaches such as HDSL and
G.

altering telepathy

A
pioneer in the use of MIMO techniques on industry standard DMT-based copper
access platforms, Aktino's products allow service providers to deliver
ubiquitous business-class broadband services to the entire CSA footprint
without further infrastructure investments.

apparently limb

The dial -in number for the conference call is 800-946-0741 (within the
United States) or 719-457-2649 (international ).

Safe Harbor Statement
This press release contains "forward-looking statements," including
statements about Lexicon's growth and future operating results, discovery and
development of products, strategic alliances and intellectual property, as
well as other matters that are not historical facts or information. Field-proven AK4000 Delivers 10 Mbps on Just 4 Pairs
Through an Entire CSA Footprint

IRVINE, Calif.