, "Smaller penises result from
undergoing the radical prostatectomy for prostate cancer," warns Dr.
He previously published "The Prostatitis Syndromes.

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Bradley
Hennenfent, author of the new book, "Surviving Prostate Cancer Without
Surgery" (Roseville Books, 2005).
Interested men should read the chapter inside "Surviving Prostate Cancer
Without Surgery" entitled: "The Radical Prostatectomy and Your Penis.S.
ICOS is marketing its product, Cialis (tadalafil), through Lilly ICOS LLC, for
the treatment of erectile dysfunction.org/FAQ/index.

(Logo: http://www .

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Men
variously described orgasms after the radical prostatectomy as "only a
shadow," "possible ," "have them but different," "some pain," and "not sure it
happens.AcousticNeuromaFoundation.SurvivingProstateCancerWithoutSurgery . Brand
Team Leader, Lilly.

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" The
book includes diagrams that realistically illustrate the damage done by the
radical prostatectomy."
Why does the radical prostatectomy damage the penis so much? "The
operation removes the prostate and seminal vesicles and removing these
structures leaves a gap that is sometimes filled by pulling the penis up into
the body, effectively shortening it, " says Dr. Hennenfent has seen five uncles suffer from prostate cancer.

,
Lilly ICOS LLC (NYSE: LLY and Nasdaq: ICOS) reported today that Cialis(R)
(tadalafil)(1), the only erectile dysfunction (ED) treatment clinically proven
to work up to 36 hours for most men, has surpassed Viagra(R) (sildenafil
citrate) in France for the second consecutive month.(3)
"We are not surprised by the success of Cialis in France, a country many
people associate with romance and love," said Matt Beebe, Cialis U.asp.

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"
"In one study [Fraiman et al."
"An animal model study [Chan et al. Hennenfent . This benefit means couples who don't want to schedule romance
can have time to relax and, for instance , have dinner or simply enjoy time
together, allowing intimacy to happen when the moment is right .
Cialis is currently available in approximately 100 countries, including
Australia, Brazil, Mexico , Canada, the United States and countries throughout
Europe.
Individual results may vary.lilly .

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These missing structures can no longer nourish the penis and it
atrophies. It's $19. Twenty-seven illustrations and cartoons are
included within the book, which also includes an extensive index.

4 percentage points of the total share of
tablets from wholesalers to pharmacies to gain the largest share of sales in
the French market. Men
taking nitrates, often used for chest pain, should not take Cialis. The most common side effects with Cialis were headache,
upset stomach, delayed backache or muscle ache.

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ROSEVILLE, Ill. "Although the cavernous nerves are sometimes spared, it
appears that the branches of those nerves, which are always cut during the
radical prostatectomy, are vital for achieving normal, completely rigid,
erections.org ), founded the
Epididymitis Foundation ( http://www.EpididymitisFoundation.5 million patients worldwide have been treated with
Cialis since its first introduction in February 2003. New York: Kensington.

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Hennenfent."
Dr.
"The success of Cialis in France is an exciting milestone for the brand
and for Lilly ICOS, especially because we joined the market after the leader
was so well established," said Leonard Blum, ICOS Vice President , Sales and
Marketing.S."

About ED
ED is defined as the consistent inability to attain and maintain an
erection sufficient for sexual intercourse. For full patient
information , visit http://www. Investors are cautioned that matters subject to forward-looking
statements involve risks and uncertainties, including economic, competitive,
governmental, technological, legal and other factors discussed in the two
companies' respective filings with the Securities and Exchange Commission,
which may affect the business and prospects of the two companies and Lilly
ICOS.

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and INDIANAPOLIS, Ind. For the
week ended April 1, 2005, Cialis held a 24 percent share of new and 22 percent
of total U. More than 4.impotence. Data accessed 11.

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(Photo: http://www.com/cgi -bin/prnh/20050503/CGTU064 )
"I can personally testify that I lost about an inch of penile length ,"
says Aubrey Pilgrim, who underwent a radical prostatectomy, "and it takes a
lot of stimulation to have an orgasm and of course it's not the same.
Hennenfent.] directly warns
physicians that: "Men should be counseled before radical prostatectomy that
penile shortening may occur. Hennenfent , "is not only that the radical
prostatectomy results in smaller penises, but that the radical prostatectomy
has failed to extend overall survival in two randomized controlled trials.Prostatitis.org ), and founded
the Acoustic Neuroma Foundation ( http://www.(5,6) In many cases, however, both psychological and
physical factors contribute to the condition. Such forward-looking statements are
based on current expectations, estimates and projections about the industry,
management beliefs and certain assumptions made by the management of ICOS and
Lilly. All other
trademarks are the property of their respective owners.

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95, a trade
paperback, 334 pages, 34 chapters, ISBN Number: 0-9717454-1-2 , and was
published January 15, 2005.com.
(2) IMS Health, IMS MIDAS(TM), France, February 2005 and March 2005. Vol.
(6) Diseases and Conditions: Impotence,
http://www.

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Men Suffer Smaller Penises after Prostate Cancer Surgery -- According to New Book

"
"The real lesson ," says Dr.
See the web site: http://www.

Cialis(R) (tadalafil) Overtakes Viagra to Become Number One Selling Erectile Dysfunction Treatment in France

In January 2005, Cialis accounted for 45 percent of the total PDE5
inhibitor tablets sold from wholesalers to pharmacies in France; Viagra 's
total for that same period was 44 percent. The
absorption of Cialis is not reduced by food , including high-fat foods. Such a
combination could cause a sudden, unsafe drop in blood pressure . Cialis studies were not designed to assess
multiple intercourse attempts after a single dose.

About Lilly ICOS LLC
Lilly ICOS LLC, a joint venture between ICOS Corporation (Nasdaq: ICOS)
and Eli Lilly and Company (NYSE: LLY), developed tadalafil for the treatment
of erectile dysfunction.

P-LLY

Except for historical information contained herein, this press release
contains forward-looking statements within the meaning of the Private
Securities Litigation Reform Act of 1995.
(4) Data were extrapolated from Feldman HA, Goldstein I, Hatzichristou
DG , Krane RJ.

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" The Savoie study found significantly smaller
penises in 124 men after prostate cancer surgery. One study suggests that the erectile tissue in the penis actually
dies off after the radical prostatectomy. "The key benefit of Cialis -- the up-to-36 hours that Cialis gives
a man and his partner to choose the moment for intimacy that's right for them
-- is the reason we have always said Cialis would succeed in the ED
marketplace. Although rare, men who
experience an erection for more than four hours (priapism) should seek
immediate medical attention.com/cgi-bin/prnh/20040122 /LILLYICOSLOGO )

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newscom.org ).
Men should discuss their medical conditions and medications , including
alpha blockers for prostate problems or high blood pressure, with their
doctors to ensure Cialis is right for them and that they are healthy enough
for sexual activity.

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"
"Surviving Prostate Cancer Without Surgery" can be found in fine
bookstores. For the month of February 2005 ,
Cialis continued its growth in France by attaining 49 percent of tablets sold
from wholesalers to pharmacies, while Viagra had the second largest share with
40 percent, according to the latest IMS market share information.com. Results and the timing and outcome of events may differ materially from
those expressed or implied by the forward-looking statements in this press
release.03
(7) Lue, Tom F. Erectile Dysfunction.

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And, in another study
[Walsh et al."
According to Dr.S. Men should not drink alcohol in excess with
Cialis. Headquartered in
Indianapolis, Ind .

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The animal model showed that when the cavernous nerve branches are
cut, softer, smaller erections occur even with chemically-induced erections. He co-
founded the Prostatitis Foundation ( http:/ /www.(2)
The market share of Cialis in France has grown consistently since the
product was introduced in Europe in February 2003., where Cialis was the third product to
enter a very competitive market, we have our own success story -- just four
months after launch, Cialis secured the second largest share of the ED market. Cialis does not protect a man or his partner from sexually
transmitted diseases, including HIV. N Engl J Med 2000; 342: 1802-1813.

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"One abstract [McCullough et al.], no man had as good an erection after surgery as before
surgery, and many men couldn't get an erection at all. Since December 2004,
Cialis has secured an additional 6. "Here in the U.(7)

About Cialis
Cialis, approved by the FDA in November 2003 for the treatment of erectile
dysfunction , is the only oral ED treatment shown to improve erectile function
up to 36 hours in most men.
Cialis is available by prescription only and is not for everyone. More specifically, there can be no assurance that Cialis will
achieve commercial success or that competing products will not pre -empt market
opportunities that might exist for the product.

(1) Cialis(R) is a registered trademark of Lilly ICOS LLC. (2002).newscom.

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Additional
information about Lilly is available at http://www. Back To Great Sex: Overcome ED and Reclaim Lost
Intimacy.

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] has documented what some of us have
already concluded from the experiences of men after prostate cancer surgery,"
says Dr . Hennenfent, another study [Savoie, et al. "In addition, nerve
branches, arteries, and veins in the pelvis are always severed by the radical
prostatectomy.
ICOS Corporation, a biotechnology company headquartered in Bothell,
Washington, is dedicated to bringing innovative therapeutics to patients. 151, 54-61,
January 1994 and World Population Projection Program Of United Nations (2002
Revision) with indirect standardization.

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Biblio Distribution (800-462-6420) and Roseville Books/Rayve
Productions (888-492-2665) distribute the book. - Cialis Achieves 49% of Total Tablet Sales
Two Years After its Successful Launch -

BOTHELL, Wash.S. oral ED treatment prescriptions. ED affects an estimated 189
million men worldwide.
(5) Shabsigh , R.

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, Lilly provides answers -- through medicines and
information -- for some of the world's most urgent medical needs.20.

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The book reveals other side effects suffered after the radical
prostatectomy including: loss of sensation to the penis, a cold penis, or a
penis that feels shriveled as if coming out of a cold swimming pool.org .(4) Experts believe that 80-90 percent of ED cases are
related to a physical or medical condition, like diabetes, cardiovascular
diseases, and prostate cancer treatment , while 10-20 percent are due to

psychological causes.cialis. ICOS is working to develop treatments
for serious unmet medical conditions such as benign prostatic hyperplasia,
cancer and inflammatory diseases.
Lilly, a leading innovation-driven corporation is developing a growing
portfolio of first-in-class and best-in-class pharmaceutical products by
applying the latest research from its own worldwide laboratories and from
collaborations with eminent scientific organizations. Impotence and its Medical and Psychosocial Correlates: Results
of the Massachusetts Male Aging Study, Journal of Urology.

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] there was a decrease in all penile
dimensions, even after 'nerve-sparing' radical prostatectomy ," says Dr.] reported a 27 percent loss in
volume of the penis after the radical prostatectomy."
Since its approval in the United States in November 2003, Cialis has
increased its share of total prescriptions every month in the U.
We're pleased to see the market share of Cialis continue to grow each month as
more and more men discover the benefits Cialis has to offer. Cialis can be taken without regard to food.
(3) IMS Health, IMS National Prescription Audit Plus7(TM), April 2005.