MediciNova's pipeline, which includes
several compounds in clinical testing, targets a variety of prevalent medical
conditions, including cancer, asthma, Generalized Anxiety Disorder , multiple
sclerosis, interstitial cystitis, preterm labor and urinary incontinence.

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The results from this trial are expected by the end of 2Q
2006.

About MediciNova
MediciNova , Inc. These
statements include statements regarding clinical trials supporting efficacy of
one of our product candidates as well as the potential novelty of that
candidate as a treatment for disease .

lifeline addictions

D. states, "In our extensive
experience with addiction treatment, using drugs, such as naltrexone ,
topiramide and acamprosate to decrease cravings can be helpful for many
individuals.

prematurity loneliness

GAD is a mental disorder consisting of chronic, excessive worry and fear
that seems to have no real cause .

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D.5 million, obsessive-compulsive
disorder 4. Such statements are subject to a number of risks and
uncertainties, many of which are beyond the control of the Company, including
the results of clinical studies and other risks and uncertainties, including
those described in the Company's filings with the Securities and Exchange
Commission.D.

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Four hundred and sixteen (416) patients have been randomized to
receive placebo or one of two flexible dose regimens of MN-305 at 25 clinical
sites in the U.

This press release may contain "forward-looking statements" within the
meaning of the Private Securities Litigation Reform Act of 1995.

For disease-related support groups, see Health/Consumer Support Groups.

dependency officium

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medicinova.com.

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Caron's medical director, Joseph Troncale, M.

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The data acquired from Mitsubishi includes extensive preclinical
and clinical safety data, including that from full carcinogenicity testing in
rodents.org.

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S.
MediciNova acquired a license to MN-305 from Mitsubishi Pharma Corporation
for global markets, with the exception of Japan and other selected Asian
countries . These statements are based on certain
assumptions made by the Company's management that are believed to be
reasonable at the time."

Nationally recognized, not-for-profit Caron Foundation offers residential
treatment and outpatient programs for adults and adolescents, as well as
families affected by the disease of addiction.

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g. These assumptions, risks and uncertainties could cause the
Company's actual results to differ materially from those implied or expressed
by the forward-looking statements. WERNERSVILLE, Pa.

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SAN DIEGO, MediciNova, Inc., Ph."
In December 2004, MediciNova initiated a randomized, double-blind,
placebo-controlled multi-center Phase II/III clinical trial of MN-305 in GAD
patients. For
more information on MediciNova, Inc.
The Caron Foundation , a national leader in chemical dependency treatment,
advocates using these medications as an adjunct to sobriety, but not as an aid
to decreased social use for people who are addicted.

obsessive unhealthy

In our opinion they are not a substitute for 12-Step recovery,
nor do these mediations that the NIH are recommending generally allow people
with addictions to moderate their use of addictive substances; once use
begins , control of drinking is lost despite use of these medications.

terminally unhealthy

, increased risk of suicide, sexual dysfunction , agitation) associated
with antidepressants currently used to treat anxiety disorders such as GAD ,"
said Yuichi Iwaki, M.
MN-305 is a novel, potent and highly selective serotonin 5-HT(1A) receptor
agonist under development by MediciNova for the treatment of anxiety disorders
beginning with GAD. This orally bioavailable compound has shown preliminary
evidence of efficacy in animal models of anxiety and in an open-label study
conducted in Japan by Mitsubishi Pharma Corporation in a group of patients
with a variety of anxiety disorders. This anxiety disorder is characterized by
the presence of excessive, uncontrollable anxiety and worry about two or more
life circumstances for six months or longer, accompanied by some combination
of restlessness, fatigue, muscle tension , irritability, disturbed
concentration or sleep, and somatic symptoms.8 million, phobias roughly 3. is a publicly traded specialty pharmaceutical company
focused on accelerating the global development and commercialization of
innovative pharmaceutical products., According to an article in The
Wall Street Journal by Jane Spencer on August 23, 2005, the NIH recently
issued updated guidelines for the treatment of alcohol-dependent patients,
encouraging family practitioners to consider drugs in addition to traditional
therapies.

abusive unhealthy

MediciNova Announces Completion of Enrollment in a Phase II/III Generalized Anxiety Disorder Trial With MN-305

These drugs may help alcoholics cut back on their drinking, rather
than give up alcohol completely. Caron operates a residential
treatment center in Wernersville, in southeastern Pennsylvania and Renaissance
Institute of Palm Beach, an extended care treatment center in Boca Raton,
Florida.

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MN-305 was well tolerated in previous
clinical studies involving over 800 volunteers and patients with either
anxiety or mood disorders.

dependency unhealthy

, please visit http://www.caron.

obsessive quitting

"MN-305 may offer effective treatment of GAD without the side effects
(e.

Any sites that can offer an opportunity to gain support, or give support, to people dealing with these issues.

A regional listing would be appropriate for information about a support group that primarily is about when and where a group meets in person.

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More than 19 million Americans
suffer from anxiety disorders: GAD affects about 4 million people, panic
disorder about 2.

addictions ding

This may include forums, email lists, personal homepages.

terminally grandparents

, Executive Chairman and Acting CEO of
MediciNova, Inc.

For more information visit http://www.

Groups and websites to help people cope with the troubles of life, or at least feel less alone.

knowing addictions

2 million and post-traumatic stress disorder about 3.2 million.

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, a specialty
pharmaceutical company that is publicly traded on the Hercules Market of the
Osaka Securities Exchange (Code Number: 4875), today announced completion of
enrollment in its Phase II/III clinical trial of MN-305 in 416 patients with
Generalized Anxiety Disorder (GAD). "Completion of enrollment in a large, pivotal-design trial
demonstrates MediciNova's commitment to advancing our clinical programs
through at least the proof-of-concept stage and into Phase III clinical
testing.

Caron Foundation Responds to the National Institute of Alcohol Abuse and Alcoholism's Updated Guidelines Regarding Treatment for Alcohol-Dependent Patients

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