Data showed:
-- Significant improvement was noted at the first post-baseline Q-LES-Q
SF assessment (week 4) in both SEROQUEL groups versus placebo (p is
less than or equal to 0.9 in
the 600 mg/day group and 19. Medical Director for
SEROQUEL.
AstraZeneca received notice on April 11, 2005, of the US Food and Drug
Administration (FDA) request that the product labeling for all atypical
antipsychotics, including SEROQUEL, be updated to include a boxed warning
noting the increased risk of mortality in elderly patients with dementia-
related psychosis taking these drugs, compared to patients taking placebo.
The FDA proposed boxed warning also notes that these drugs are not approved
for treatment of elderly patients with dementia-related psychosis. AstraZeneca is listed in the Dow Jones Sustainability Index
(Global) as well as the FTSE4Good Index. Mayo Clinic on Depression.: Mayo
Clinic Health Information, 2001. The Visible
Path platform applies the science of social network analysis to allow
professionals to access the entire enterprise's trusted relationship
network without invading privacy or compromising relationships. The
platform integrates tightly with corporate applications to measurably
accelerate sales cycles, increase close rates, and reduce the cost of
lead generation and customer acquisition.

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- Study Showed Significant Improvement in Quality of Life Measures -

WILMINGTON, Del.(3)

IMPORTANT SAFETY INFORMATION
SEROQUEL is indicated for the treatment of acute manic episodes associated
with bipolar I disorder, as either monotherapy or adjunct therapy with lithium
or divalproex, and the treatment of schizophrenia.

The first award will be in 2006. The
White Paper analyzes the patterns of these violent incidents, methodological
problems with collecting crime data, and underlying issues , such as sports
culture and alcohol use. For more information, visit http://www.acha.

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"
The BOLDER study, an eight-week, double-blind, placebo-controlled trial,
assessed SEROQUEL 300 mg/day and 600 mg/day versus placebo for the treatment
of depression in 542 patients with bipolar I and II disorders.4
billion and leading positions in sales of gastrointestinal, cardiovascular,
respiratory , oncology and neuroscience products. The association is a non-profit
organization incorporated in the state of Delaware with members from
Argentina, Australia, Austria, Belgium, Brazil, Canada, Denmark ,
Finland, France, Germany, Ghana, Greece, Hong Kong, Hungary, Ireland,
Israel, Italy, Japan, Korea , Mexico, Netherlands, Norway, Poland,
Russia, Singapore, Slovenia, South Korea, Spain, Sweden, Switzerland ,
Taiwan, UK and USA. Data from the Spring
2004 ACHA-National College Health Assessment (ACHA-NCHA ) indicates that out of
a sample of 47,202 students, 15.acha.org/info_resources/guidelines.

'Transgenderism ' is an umbrella term covering persons who do not fit societal expectations of sex or gender.

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Patients starting treatment with
atypical antipsychotics who have or are at risk for diabetes should undergo
fasting blood glucose testing at the beginning of and during treatment.
Annual Meeting of the American Psychiatric Association, 2005,
Atlanta, Georgia, poster 327.

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Patients should be
periodically reassessed to determine the need for continued treatment.

Business Editors /High-Tech Writers
Sunbelt XXV International Social Network Conference

REDONDO BEACH, Calif . Funds for the award are provided
by Visible Path Corporation. Visible Path Corporation,
founded in 2002, is a privately-held company with investment from
Kleiner Perkins Caufield + Byers.

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The Q-LES-Q SF is a common measurement tool used to assess quality of life in
patients experiencing depression .com

(1) Endicott J, Rajagopalan K, Macfadden W, et al. Efficacy of quetiapine
in improving quality of life in patients with bipolar depression. Submitted papers will be evaluated by a committee of four
judges; their decision will be final. The paper must be written between September 1, 2004 and
August 31, 2005.edu

About INSNA

INSNA is the professional association for researchers interested
in social network analysis.0% of men reported being in a
sexually abusive relationship within that time frame.

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, AstraZeneca (NYSE: AZN)
today announced additional findings at the annual meeting of the American
Psychiatric Association (APA) from the BOLDER (BipOLar DEpRession ) trial, a
large-scale study that examined SEROQUEL as a treatment for depressive
episodes in patients with bipolar I and II disorders.
"The depressive phase of bipolar disorder, which patients experience
approximately three times as often as the manic phase, is associated with
significant impairment in quality of life.seroquel.

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(1)
SEROQUEL is approved for the treatment of acute manic episodes associated
with bipolar I disorder and for the treatment of schizophrenia. Quality of life is of critical
importance for patients with bipolar disorder because they often experience
relationship and work problems," said Jean Endicott, Ph., U. "The results of this analysis are exciting, and reinforce the
importance of additional investigation of SEROQUEL in managing depressive
symptoms associated with bipolar disorder.
Prescribing should be consistent with the need to minimize the risk of
tardive dyskinesia. A rare condition referred to as neuroleptic malignant
syndrome has been reported with this class of medications, including SEROQUEL. A randomized, double-blind, placebo-controlled trial of
quetiapine in the treatment of bipolar I or II depression. Letters of support should be submitted as well.
According to the U. "Prevention programs are the key, and successful ones
require commitment from health professionals and administrators.

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Results from this trial
showed SEROQUEL (600 mg/day and 300 mg/day) significantly improved quality of
life measures on the Quality of Life Enjoyment and Satisfaction Questionnaire
(Q-LES-Q SF)., professor of
Clinical Psychology in the Department of Psychiatry at Columbia University and
Chief of the Department of Research Assessment and Training at the New York
State Psychiatric Institute.
Without appropriate treatment, patients usually suffer for a lifetime with
periods of wellness and functioning punctuated by severe episodes of
illness.

The International Network for Social Network Analysis Announces Visible Path Graduate Student Award

4% of women and 1. "Campus violence can seriously affect student learning
and their mental and physical health, making it a health problem that requires
immediate attention," said Joetta L.

Transgendered persons include: transsexuals, cross-dressers, drag-queens, butch lesbians, intersexuals , and others.

disparate sexology

Data presented
today analyzed quality of life in these patients using the Quality of Life
Enjoyment and Satisfaction Questionnaire (Q-LES-Q SF), a 16 item, self-report
survey that measures differences in the degree of enjoyment and satisfaction
among groups of patients, as well as changes over time in a single patient.5) (p is less than or equal to 0.D.

ABOUT ASTRAZENECA
AstraZeneca is a major international healthcare business engaged in the
research, development , manufacture and marketing of prescription
pharmaceuticals and the supply of healthcare services .
For more information about AstraZeneca, please visit
http://www.
INSNA will give the annual award, which carries a $5,000 prize
plus paid expenses to the Sunbelt conference, to a graduate student in
recognition of research on how social networks are used to improve
individual and inter-organizational performance.
"The timing is right for graduate students looking to discover new
insights on social network that can advance an increasingly popular
discipline with growing opportunities for application ," said Stanley
Wasserman, professor of sociology, psychology, and statistics at
Indiana University and chief scientist for Visible Path Corporation in
New York.S. Department of Justice's Violent Victimization of
College Students survey, between 1995 and 2002 students ages 18-24 were
victims of approximately 479,000 violent crimes annually.0% of women and 9.org.

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001) (1)
-- Q-LES-Q SF mean percentage change scores at final assessment (LOCF)
were significantly greater in both SEROQUEL treatment groups (20."

ABOUT BIPOLAR DISORDER
Bipolar I disorder consists of recurring episodes of mania with or without
depression.
Precautions include the risk of seizures, orthostatic hypotension and
cataract development. It is one of the
world's leading pharmaceutical companies with healthcare sales of over $21. In the United States,
AstraZeneca is a $9.

Address for submission (electronic submissions in PDF file-format
required):
Professor Ronald Burt
Chair, Visible Path Graduate Student Award Committee
Graduate School of Business
University of Chicago
5807 South Woodlawn Avenue
Chicago, Illinois 60637
Ronald.

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About Visible Path Corporation

Visible Path transforms the way large companies leverage
relationship capital to drive top-line revenue growth.

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D.(3) Both men and women are equally at risk for this illness, which
most often emerges in adolescence or young adulthood and recurs throughout
life.

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S.

Eligible students must be first (or sole) author on
the submitted paper.cfm.

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"These data from the BOLDER trial are important
because they recognize that quality of life is a key dimension of treatment in
bipolar disorder.astrazeneca-us.
(3) Kramlinger K. The awardee
will give a formal presentation at the Sunbelt 2006 conference in
Vancouver .uchicago. BALTIMORE, In an effort to confront the issue of
campus violence at college and universities , the American College Health
Association (ACHA) has released a White Paper that chronicles the scope of the
problem, presents significant data, and recommends models for prevention.

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The term "campus violence" includes shootings, murder-suicide, homicide,
suicide, rape, dating violence, harassment , assault, stalking, hazing, arson,
and hate crimes based on gender, race, ethnicity, or sexual orientation .

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3 in the 300 mg/day group) than in the
placebo group (11.com. Judging will be on the basis of
the level of originality in the ideas and techniques, the possible
applications and their treatment , and potential impact.burt@gsb.2% of men report being in an
emotionally abusive relationship within the last school year.

societal clinicians

Patients who develop symptoms of hyperglycemia should also undergo fasting
blood glucose testing.6 billion healthcare business with more than 12,000
employees. ACHA-NCHA data
also revealed 2.7% of women and 1.

Academic perspectives on transgenderism come from many disciplines such as psychology, history, sociology, anthropology, gender studies, queer studies, and law.

dsm psychopathology

3% of men reported being in a physically
abusive relationship and 1."
The White Paper is available online at
http://www.

transtudies distract

(3) In the long term, patients with bipolar I disorder
experience depressive symptoms three times longer than manic symptoms. Rochester, Minn. The paper also focuses on legal mandates, policy
recommendations, and promising practices to help prevent the problem.

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Bipolar II disorder consists of recurring episodes of hypomania
and depression.(2)
Patients with bipolar II disorder have traditionally been difficult to treat
as they spend almost forty times longer in the depressed state than in mania . October
28, 2004 Manuscript. "This award seeks to
encourage research for benefit of everyone who is interested in the
juncture of social network analysis and organizational performance.

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SEROQUEL is
currently under investigation for use in the treatment of bipolar depression.
Hyperglycemia , in some cases extreme and associated with ketoacidosis,
hyperosmolar coma or death, has been reported in patients treated with
atypical antipsychotics, including SEROQUEL.
The most commonly observed adverse events associated with the use of
SEROQUEL in clinical trials were somnolence, dry mouth , dizziness,
constipation, asthenia, abdominal pain, postural hypotension, pharyngitis,
SGPT increase , dyspepsia, and weight gain.
The committee may arrive at the conclusion that none of the submitted
papers merits the award.
ACHA is committed to deconstructing campus violence through the
circulation of its White Paper and by tapping into its members' experiences in
addressing this issue.

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Data Further Examines SEROQUEL(R) (quetiapine fumarate) Treatment for Bipolar Depression

"
To apply for this year's award, students submit a paper to INSNA's
Visible Path Graduate Student Award Committee before September 1,
2005. Carr, PhD, chair of the ACHA Campus
Violence Committee.

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001) (1)
-- The most common adverse events in the trial included dry mouth,
sedation or somnolence , dizziness and constipation (1)

"Improved quality of life is key in helping patients manage bipolar
disorder symptoms," said Wayne Macfadden, M.
"Social network analysis touches many disciplines -- anthropology,
sociology, psychology, political science, economics, medicine, urban
planning and communications science for starters - yet there are few
awards that are specifically designed to support basic social network
research," said Bill Richards, INSNA president and professor of
communications at Simon Fraser University.

The American College Health Association, the nation's principal advocate
and leadership organization for college and university health, represents a
diverse membership that provides and supports the delivery of health care and
prevention and wellness services for the nation's college students. Ongoing
efforts such as the Campus Violence White Paper and ACHA-National College
Health Assessment help the association advocate for student health by
integrating the critical role of college health into the mission of higher
education.

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For full Prescribing Information for SEROQUEL, please visit the Web site
http://www.
(2) Calabrese JR, Keck PE , Macfadden W, et al, for the BOLDER Study
Group.----

Award Recognizes Research on How Social Networks Improve
Professional Performance

The International Network for Social Network Analysis (INSNA)
announced a newly-created Visible Path Graduate Student Award at the
Sunbelt XXV International Social Network Conference here today."
The award stems from a widening interest in social network
analysis sparked by articles, popular books and new companies selling
web services and software that capitalize on social networks. Barry Wellman founded INSNA in 1978; the current
president is Bill Richards.

American College Health Association White Paper Examines Violent Acts on College and University Campuses

psychopathology distress

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