For more than 40 years, Pampers
has been helping to improve life for babies, toddlers, and the parents who
care for them. children, and is considered the most commonly
diagnosed psychiatric disorder in children and adolescents. ADHD is a
neurological brain disorder that manifests as a persistent pattern of
inattention and/or hyperactivity-impulsivity that is more frequent and severe
than is typically observed in individuals at a comparable age and maturity. ADDERALL XR was generally safe and well
tolerated with adverse events similar to those seen in other populations.

About ADDERALL XR
ADDERALL XR may not be right for everyone.
"'A CRY FOR LIGHT' will help prepare families who choose to embark on
helping hurt children," says Gregory C. Keck, Ph.

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The online home of the PPI
board, Pampers.
Pampers knows babies and parents. Recognizing the growing importance
of the Internet for moms and dads, Pampers is now launching an improved Web
site that is easier to navigate and lets parents personalize the site and view
the exclusive articles, parenting tips and advice to their baby's stage of
development. Pampers is used by more than 35 million babies around the
world each day and is the world's top selling diaper brand .
"There has long been an unmet need for ADHD research and treatment among
the adolescent population despite an increasing awareness of ADHD's potential
impact on quality of life. Stimulant therapies are effective and generally well
tolerated, and have been used medically in patients for more than 60 years. The results of this study show that ADDERALL XR produces a
positive clinical response in adolescents diagnosed with ADHD. May is National Foster Care Month

LOS ANGELES, It happens all across America.
"Rapid adoptions," says Jackson, "can minimize RAD.

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com/cgi-bin/prnh/20050607/LATU005)
In addition to the parenting content already available at Pampers.
To coincide with the introduction of the Pyramid, Sesame Workshop has
created a series of activities, available at SesameBeginnings. For example, there
are fun games that encourage an infant to visually follow a moving object that
are appropriate during the 0 to 5 months stage . The Pampers
Developmental Record Booklet and Baby Stages of Development Pyramid help guide
parents and Pampers.com features a wealth of information that comes directly
from other parents, as well as health professionals and childcare experts on
the PPI board."
ADHD affects approximately 3 to 7 percent of all school-age children, or
approximately two million U. In the event such
risks or uncertainties materialize, Shire's results could be materially
affected.

The Painful Secret Life of Some Adoptive Parents

"RAD is a traumatic experience for many parents. Few mental health experts specialize in RAD treatment
which makes it difficult for families to find help.

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D. The company has one of the strongest portfolios of trusted, quality,
leadership brands, including Pampers(R) , Tide(R), Ariel(R), Always(R),
Whisper(R), Pantene(R), Bounty(R), Pringles(R), Folgers(R), Charmin (R),
Downy(R), Lenor(R), Iams(R), Crest(R), Actonel(R), Olay(R), Clairol Nice 'n
Easy(R), Head + Shoulders(R), and Wella(R). " We are pleased that a thorough review by the
FDA once again confirms the safety and efficacy of Adderall XR in another age
group. Shire has operations in the world's
key pharmaceutical markets (US, Canada, UK, France, Italy, Spain and Germany)
as well as a specialist drug delivery unit in the US., Shire's ability to secure new products for
commercialization and/or development and other risks and uncertainties
detailed from time to time in Shire's filings with the Securities and Exchange
Commission, including its Annual Report on Form 10-K for the year to December
31, 2004. When the adoption finalizes, and the
honeymoon stage is over, some children 's behaviors become so difficult that
the adoptive parents want to return them. Some do. Founder , Director
Attachment and Bonding Center of Ohio.

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When It Comes to Good Parenting It's What You Know and Who You Know

Pampers Parenting Institute Childcare Experts Offer New Tools for Parents -
Free Developmental Record Booklet and Pyramid - at Newly Redesigned
Pampers."

Baby Stages of Development Pyramid + Activities
Pampers is pleased to help parents make learning about their child a
little easier.

About Pampers
Pampers(R) is a trademark of Procter + Gamble (NYSE: PG) and the company's
largest and first $7 billion global brand. Timothy
Wilens of Massachusetts General Hospital., at
school and home); and that the symptoms continue for at least six months.
For further information on ADDERALL XR, please visit the ADDERALL XR
website at http://www. Jackson, adopted two of their three
children.

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Pampers and the Pampers Parenting Institute (PPI), an independent advisory
board of renowned maternal and child health experts, have introduced the Baby
Stages of Development Pyramid, an easy-to-reference visual tool that helps
guide parents through their child's stages of development from birth to 24 +
months. A recent survey showed that even experienced moms and dads
wish for more information about their child's developmental milestones. We encourage parents to visit SesameBeginnings. I'm thrilled to be a part of the team that helps deliver this
important information to parents around the world. Find the
Workshop online at http://www.

maggy leibert

(Photo: http://www.
Abuse of amphetamines may lead to dependence. RAD
children fail to develop a conscience, are non-compliant , demand to stay in
control, and do not trust."
Jackson who owns Self Awareness Trainings with her husband, facilitates
workshops on team building.

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"To a parent, nothing is more important than raising a happy,
healthy baby. The Pyramid shows how each stage builds
on the previous one and encourages parents to anticipate and celebrate the
breathtaking changes babies and toddlers undergo in the early years. Our business is
inspired by babies and toddlers, created by Pampers. Sesame Workshop is behind
award-winning programs like Dragon Tales and Sagwa, The Chinese Siamese Cat
and ground breaking multimedia productions in South Africa, Egypt and Russia. for treatment in
children aged 6 to 12 years and since August 2004 in adults 18 years and
older. As they age, up to 65 percent of adolescents
with ADHD may still exhibit symptoms into adulthood. The study
showed ADDERALL XR at doses between 10 mg and 40 mg daily were statistically
significantly superior to placebo (p<0 . ADDERALL XR was generally well
tolerated in clinical studies. Misuse of amphetamine may
cause sudden death and serious cardiovascular adverse events. Many come from foster care,
and orphanages around the world," said Jackson. "Parents don't know about
RAD, let alone how to handle their child with this condition.

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Evidence also suggests that many with untreated
ADHD may be at risk for other problems, such as drug abuse, anti-social
behavior and poor self-esteem. Furthermore, 63 percent
of investigators considered their subjects' ADHD symptoms to be much improved
or very much improved with ADDERALL XR compared to 27 percent for placebo
(p<0. ADDERALL
XR should be prescribed with close physician supervision.com/cgi-bin/prnh/20050524/LATU003)
In the new book, "A Cry for Light: A Journey into Love," (releases
June 2005 http://www. When the child is finally placed in Jackson 's
home, her family is ripped apart by Devon's condition, Reactive Attachment
Disorder (RAD)."
Reactive Attachment Disorder (RAD) is appearing more frequently in society
and in children today with individuals who have difficulty forming loving,
lasting intimate relationships. Some end up in the justice system. "He was born with drugs and
alcohol in his system, physically and sexually abused, and lived in two foster
homes.

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Please visit
http://www. Founded in 1968,
the Workshop changed television forever with the legendary Sesame Street.

(1) 2000 National Survey of Early Childhood Health (NSECH)

(2) March 2005 Synovate online survey on behalf of Pampers of 404 parents
with children between the ages of birth and six years of age.

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With both online and offline resources and long-term
relationships with respected parenting resources -- including nonprofit
educational organization Sesame Workshop -- Pampers has become a brand that
parents look to for support and information as they embark on the thrilling
journey of parenthood. The Pyramid was designed to provide information on key
developmental milestones in a colorful, easy-to-read format.

About P+G (NYSE: PG)
Two billion times a day, P+G brands touch the lives of people around the
world. PHILADELPHIA, Shire Pharmaceuticals
Group plc (LSE: SHP, Nasdaq: SHPGY, TSX: SHQ) announced today that the US Food
and Drug Administration (FDA) has approved ADDERALL XR(R) (mixed salts of a
single-entity amphetamine product) as a once -daily treatment for adolescents
aged 13 to 17 with attention deficit hyperactivity disorder (ADHD ).
"The new adolescent labeling for ADDERALL XR offers health care providers,
parents and patients continuity in the management of ADHD symptoms as children
become older," said Greg Flexter, Executive Vice President and General
Manager, Shire North America. Many are too
embarrassed to talk about it.

Information for parents with disabilities or parents of children with disabilities.

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With the
Developmental Record Booklet, parents easily can keep track of their child's
health and development in one convenient place for use at home and during
visits with their child's health care provider.com while supplies last. Therefore, approval of an ADHD treatment for this
underidentified age group is an important milestone," explained Dr.

About ADHD
ADHD is a neurobiological disorder that manifests as a persistent pattern
of inattention and/or hyperactivity-impulsivity more frequent and severe than
typically observed in individuals at a comparable level of development. Such forward-looking statements involve a number of risks
and uncertainties and are subject to change at any time. Professionals placing disturbed children in families will
get an inside look as to why so many parents adopting children with high
levels of disturbance look so crazy after a placement has been made.

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For more information on
Pampers and the Pampers Parenting Institute, visit http://www.pg.

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"
Sesame Workshop , as the producers of the beloved Sesame Street educational
TV series, has a long-standing history of helping children as they reach their
highest potential.
Today, the Workshop continues to innovate on behalf of children in
120 countries, using its proprietary research methodology to ensure its
programs and products are engaging and enriching.sesameworkshop. These data included the results of a
pharmacokinetic study and a placebo-controlled, fixed-dose clinical trial of a
range of doses of once-daily ADDERALL XR in adolescents with ADHD. ADDERALL XR
generally should not be used in children or adults with structural cardiac
abnormalities.

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newscom.com for a limited time.com, to find out more
about what they can be doing at each stage of development to bond with their
child and help promote early learning. Since
October 2001, ADDERALL XR has been approved in the U. Untreated ADHD has
long-term adverse effects on academic performance, vocational success and
social-emotional development.com .

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com has launched with a brand new look and easier-to-use
navigation to assist parents with questions and information when they need it
at any time.com and linked to Pampers. For example,
toddlers generally take their first steps at 13 to 18 months, and begin
make -believe play at 19 to 23 months., Director of
General and Community Pediatrics at Cincinnati Children 's Hospital Medical
Center, Associate Chair of Pediatric Education at the University of Cincinnati
College of Medicine, PPI Board member and Chairperson for the American Academy
of Pediatrics' Committee on Pediatric Education.0001) on the ADHD-RS-IV
(investigator-rated with the parent and adolescent)."
The author who took Devon to 25 different therapists before finding help,
hopes RAD awareness will bring more available treatment since conventional
therapy often fails.

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They are supporting Pampers' efforts to bring tools to
parents that help them foster their child's development through a series of
activities available on SesameBeginnings. "Our new Sesame Beginnings is a brand
specifically designed to provide parents and caregivers with tools they can
use to promote interaction between them and their little ones under the age of
two.S.
ADHD can have a profound effect on a child's quality of life and can be
serious enough to interfere beyond academics, leading to problems maintaining
friendships, difficulties focusing on sports or other after-school activities,
and challenges in relating well with other family members. The most common side effects in the adolescent trial included loss
of appetite, insomnia, abdominal pain, and weight loss.
Although there is no "cure" for ADHD, there are accepted treatments that
specifically target its symptoms. The most common standard treatments include
educational approaches, psychological or behavioral modification , and
medication. The risks and uncertainties include, but are not limited to, risks
associated with the inherent uncertainty of pharmaceutical research, product
development, manufacturing and commercialization, the impact of competitive
products, including, but not limited to, the impact of those on Shire's ADHD
franchise, patents, including but not limited to, legal challenges relating to
Shire's ADHD franchise, government regulation and approval, including but not
limited to Health Canada's suspension of ADDERALL XR(R) sales in Canada and
the expected product approval dates of MTS (METHYPATCH) (ADHD), SPD503 (ADHD),
SPD465 (ADHD), SPD476 (ulcerative colitis), and NRP104 (ADHD ), including its
scheduling classification by the Drug Enforcement Agency in the United States,
Shire 's ability to consummate and benefit from its proposed acquisition of
Transkaryotic Therapies, Inc . Devon fit the classic RAD profile.

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Yet
survey data shows that only about half of parents of young children report
ever discussing their child's development with a pediatrician. ADDERALL XR is currently the most commonly prescribed brand of ADHD
medication in the United States.

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"While children develop at
different rates, there are milestones parents should anticipate."

What's New at Pampers . The P+G community consists of
almost 110,000 employees working in over 80 countries worldwide.

com for the latest news and in-depth information about P+G and its
brands.
In a randomized , double-blind, placebo-controlled clinical trial, ADDERALL
XR was proven to be significantly more effective than placebo in the treatment
of ADHD symptoms in adolescents.0001). The most common adverse events in pediatric
trials included loss of appetite, insomnia, abdominal pain, and emotional
lability . The most common
adverse events in the adult trial included dry mouth, loss of appetite,
insomnia , headache, and weight loss. When left
untreated, individuals can become sociopaths, and in extreme cases, violent.

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com

Sesame Workshop Creates Developmental Stage-Related Activities on
SesameBeginnings.(1) That's why
Pampers is offering new tools like the Pyramid and corresponding booklet for
parents to use during well child visits.
"Parenting is a wonderful and challenging journey," said Kirk Perry, North
America Vice President and General Manager, Pampers Baby and Toddler Care, and
father of four.
"Parents know Sesame Workshop for its child development expertise , and
trust Sesame Street for its broad-reaching and engaging educational content,"
said Liz Kalodner , Executive Vice President and General Manager, Global
Consumer Products, Sesame Workshop.

What Parents Told Us
A recent survey of parents with children between the ages of birth and six
years sponsored by Pampers(2) shows that sometimes even experienced parents
need and want more information about their child's development and key
milestones.
As a nonprofit, Sesame Workshop puts the proceeds it receives from sales of
Sesame Street, Sesame Beginnings, Dragon Tales and Sagwa products right back
into its educational projects for children around the world.
Couples wait endlessly to adopt a child.newscom. "It will provide a great reality check
for those families already in the middle of something they had no idea they
would be facing.

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Pampers is honored and thrilled to partner with other parents
to help them learn more and support their baby's development.com.org . "The symptoms of ADHD often
continue past childhood into adolescence and adulthood, where they can have a
significant impact on an individual's family, academic performance, and
overall quality of life.
The effectiveness of ADDERALL XR for long-term use has not been
systematically evaluated in controlled trials.

"SAFE HARBOR" STATEMENT UNDER THE PRIVATE SECURITIES LITIGATION REFORM ACT
OF 1995
Statements included herein that are not historical facts are forward-
looking statements.janetajackson.

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com,
Pampers is introducing several new resources to further partner with parents. In fact, parents regularly share their
thoughts with Pampers on parenting including their successes, frustrations,
wants and needs.
They are easy activities that parents can do with their child to support their
cognitive, physical, social and emotional development, which can be reinforced
every time parents feed, bathe, or play with their child.

"Parents need to feel comfortable asking their health care providers
questions about their child's development," said Tom DeWitt, M . Pampers.

FDA Expands Indication for ADDERALL XR(R) (CII) Confirming Safety and Efficacy in Adolescents

ADDERALL XR is contraindicated in patients with symptomatic
cardiovascular disease, moderate to severe hypertension, hyperthyroidism and
glaucoma, known hypersensitivity to this class of compounds , agitated states,
history of drug abuse, or current or recent use of MAO inhibitors. To be
properly diagnosed with ADHD, a child needs to demonstrate at least six of
nine symptoms of inattention; at least six of nine symptoms of
hyperactivity/impulsivity; the onset of such symptoms before age 7 years; that
some impairment from the symptoms is present in two or more settings (e.g.

For further information please contact:

Media Marion Glick (Porter Novelli) (212) 601 -8273
Janice Miller (Porter Novelli) (212) 601-8176

Notes to editors

Shire Pharmaceuticals Group plc
Shire Pharmaceuticals Group plc (Shire) is a global specialty
pharmaceutical company with a strategic focus on meeting the needs of the
specialist physician and currently focuses on developing projects and
marketing products in the areas of central nervous system (CNS),
gastrointestinal (GI), and renal diseases. There are thousands of
hurt and damaged children who have this disorder.

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Consistent with the colors and stages outlined in the Pyramid, Pampers has
designed its Baby Stages "Changes with Me" product line-up of diapers and
disposable pants specifically for every stage of a baby's development.com
Both the Pyramid and the Developmental Record Booklets are available for
free at Pampers.pampers. The
most common adverse events were loss of appetite, insomnia, abdominal pain,
and weight loss. A side effect seen with the amphetamine class is
psychosis. The disorder varies in severity."

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com to Encourage Parent/Child Interaction and a Love of
Learning

CINCINNATI, Pampers(R), a trusted name in baby and
toddler care for more than 40 years, surrounds parents with easy-to-access
information regarding their babies' and toddlers' health, development and
well-being.

About Sesame Workshop
Sesame Workshop is a nonprofit educational organization making a
meaningful difference in children's lives around the world."
The FDA based its approval on data that Shire provided in a supplement to
its New Drug Application (sNDA).AdderallXR.
(Photo: http://www. Keck is
the Co-author of "Adopting the Hurt Child," and "Parenting the Hurt Child. The former publicist for ABC and CBS Television
Networks was a CASA, Court Appointed Special (child) Advocate who saw many RAD
children coming through the child welfare system.

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The Pyramid is featured in a new, free Developmental Record Booklet
now available to parents at Pampers.com.com, that help
foster development and a love of learning through parent/child interactions. The survey showed that:
* Only one -third (33 percent) of parents knew the average age for a
baby's first steps;
* Only half (50 percent) knew when to expect their baby's first words;
* An overwhelming 96 percent felt that it was important to have
information about their child's developmental milestones; and
* More than 80 percent of experienced moms said they would have found
information on their baby's development milestones useful once they
had their first child.com, one of the most popular branded baby care Web
sites, will continue to offer parents terrific tools and resources such as a
pregnancy calendar, potty training guide and new videos to become more in tune
with their baby's development. As with other psychostimulants
indicated for ADHD, there is a potential for exacerbating motor and phonic
tics and Tourette's syndrome. Caution also should be exercised in patients with a history of
psychosis.com), Janet Alston Jackson recounts her struggles
to adopt Devon, a three-year-old trapped in the Los Angeles Department of
Children and Family Services.
Jackson and her husband Walter H. Frustrated and angry
parents often give up on the child.