About Ardent Health Services

Ardent Health Services is a provider of healthcare services to
communities throughout the United States. These risk factors include, among
others, limited operating history and lack of statistically
significant formal research studies, difficulty in developing,
exploiting and protecting proprietary technologies, intense
competition and substantial regulation in the healthcare industry; and
additional risks factors as discussed in the reports filed by the
company with the Securities and Exchange Commission , which are
available on its website at http://www.sec.gov

National
media coverage , as well as studies in Europe, Asia and Africa have
spoken to the gravity and scope of this problem , highlighting the link
between methamphetamine addiction, increased transmission of disease
and escalating criminal behavior. Dr.
Consequently, within this scientific situation, an open label trial
which shows positive results would be very valuable for the treatment
community, as it would be a jumping off point on which to focus more
detailed double-blind placebo-controlled trials."
In November 2004, Hythiam announced it had established a Clinical
Outcomes Registry for the monitoring and evaluation of patients
undergoing Hythiam's HANDS Protocols(TM) for alcohol and/or stimulant
dependence at commercial licensee locations.; and New York. These forward-looking statements reflect numerous assumptions
and involve a variety of risks and uncertainties, many of which are
beyond the company's control, that may cause actual results to differ
materially from stated expectations .

tomkins wfs

Changes in the neurochemistry of the brain
underlie the hallmarks of substance dependency, including craving,
tolerance, withdrawal symptoms and relapse."
Dr."
Dr.

methamphetamines nickscape

Urschel has worked for years designing addiction treatment
protocols and treating patients with various substance dependencies ,
including alcohol, cocaine and methamphetamine.
Dr.

About HANDS(TM)

Hythiam's HANDS Protocols(TM) are designed for use by healthcare
providers to treat those diagnosed with dependencies to alcohol,
cocaine, methamphetamine and other addictive stimulants, as well as
combinations of these drugs.; Reading, Pa.

unanimous methamphetamines

The agreement calls for licensing of the HANDS(TM) Protocols
initially into five Ardent Health Services behavioral hospitals - BHC
Alhambra Hospital, a full service psychiatric hospital that offers
inpatient, partial hospitalization, eating disorder and substance
abuse treatment , located in California's San Gabriel Valley;
Intermountain Hospital, a full service psychiatric hospital and
residential treatment center located in Boise, Idaho; Montevista
Hospital, a full service psychiatric hospital offering inpatient and
outpatient services for behavioral, chemical detox and rehabilitation,
located in Las Vegas, Nevada; West Hills Hospital, a behavioral health
care services facility offering inpatient hospitalization, chemical
detox and rehabilitation, and intensive outpatient psychiatric and
chemical dependency treatment, located in Reno, Nevada; and Fairfax
Hospital, a full-service psychiatric hospital located in Kirkland,
Washington, a suburb of Seattle, that provides treatment services for
adults, adolescents, and children through inpatient and partial
hospitalization .
Research Across America has conducted over 1,000 clinical trials for
more than 50 pharmaceutical companies, as well as most contract
research organizations and numerous biotech companies. Urschel 's study of the HANDS Protocol will include 30 men and
women, 18-65 years of age, who are dependant on methamphetamine,
according to the criteria as defined by the Diagnostic and Statistical
Manual of Mental Disorders - Fourth Edition (DSM-IV). Since the aim of
the study is to initiate abstinence from methamphetamine, patients
will not be required to be drug or stimulant abstinent at the time of
enrollment and treatment. The methamphetamine
molecule itself is extremely destructive to the cells in and around
many important pathways within the brain. The organization
is physician owned and operated, maintaining the highest medical
standards for patient care and data integrity.

counselers silvan

As a result, the HANDS
Protocols represent a comprehensive approach to managing substance
dependence that is designed to address both the physiological and
psychological aspects of the disease, thereby offering patients an
opportunity to transition into a healthier lifestyle. These forward-looking statements reflect numerous assumptions
and involve a variety of risks and uncertainties, many of which are
beyond the company's control that may cause actual results to differ
materially from stated expectations.A. The CNS
Research Group for Research Across America is headed by Dr. Urschel has conducted a number of
notable studies, including the investigation of a new 30-day injection
medication for the treatment of alcoholism and the evaluation of
several new medications for the treatment of cocaine dependency.com

Forward-Looking Statements

Except for statements of historical fact, the matters discussed in
this press release are forward looking and made pursuant to the Safe
Harbor provisions of the Private Securities Litigation Reform Act of
1995.

alano counselers

The HANDS Protocols include medically
supervised procedures designed to target receptor sites in the brain
that regulate neurotransmitters implicated in brain processes of
substance dependency.

silvan vanduo

"
"The HANDS(TM) Protocol, especially because of its emphasis on
addressing both the physiological and psychological causes of the
disease of addiction, lends itself to the outpatient services approach
of our facilities ," said Harry Silsby, M. Peizer, Hythiam's Chairman
and CEO.

About Research Across America

Located across the country, Research Across America is a group of
independent, professional clinical research sites that provide various
medical study capabilities. For further information please visit www.

wfs vanduo

(AMEX:HTM), a healthcare services management company
that delivers to treatment providers both proprietary administrative
services and physiological protocols designed to treat addiction,
announced today that it has signed a licensing and services agreement
to offer its HANDS(TM) Protocols to Ardent Health Services, a leading
network of behavioral hospitals and one of the largest providers of
inpatient and outpatient mental health services.

About HANDS(TM )

Hythiam's HANDS(TM) Protocols are designed for use by healthcare
providers to treat those diagnosed with dependencies to alcohol,
cocaine, methamphetamine and other addictive stimulants, as well as
combinations of these drugs.D. The study will consist of an initial
three-day outpatient treatment for each patient, followed by an
additional two-day cycle after three weeks, and a 12-week follow up
and assessment period.

meth dysfunctional

, M. Urschel explained, "The HANDS Protocol(TM) for Stimulant
Dependence is a promising new treatment option for those with
methamphetamine dependence. The HANDS Protocols also
provide for a maintenance program that includes medications and
incentives for patients to continue with the recovery process through
individualized continuing care programs.

parkcrest reinforce

To date there have been no clear-cut effective
treatments, either pharmacological or behavioral which are readily
available for this pervasive devastating illness.

wfs reachout

Veteran Clinical Researcher Dr. Harold Urschel to Investigate Hythiam's HANDS Protocols for the Treatment of Methamphetamine Dependence; First of Several Antic

, intends to conduct
a study of Hythiam's HANDS Protocols(TM) in the treatment of
methamphetamine dependence. Upon final approval to begin the study, each qualified
subject will participate in the trial over a three month period in
Dallas, at the Research Across America clinical research facility . An accomplished
researcher, over the past 15 years he has designed and conducted many
studies targeted at addiction recovery, both for governmental agencies
like the National Institute on Drug Abuse (NIDA) and major
pharmaceutical companies. Among the neuronal pathways targeted by
the components of the HANDS Protocols(TM) is the GABA system,
including the GABA(A) receptor. Moreover, as
the major inhibitory neurotransmitter in the central nervous system,
GABA plays a pivotal role in maintaining stable and rational behavior. Specific imaging data have
shown that normal brain function may take as long as up to a year and
a half with complete sobriety after the use of methamphetamine. As a result, the HANDS
Protocols represent a comprehensive approach to managing substance
dependence that is designed to address both the physiological and
psychological aspects of the disease, thereby offering patients an
opportunity to transition into a healthier lifestyle.

reinforce addicted

M. An analogy would be that the circuit
breakers within this important brain pathway have flipped off, and
consequently there is significantly impaired control in the normal
functioning of this pathway in methamphetamine and other addictions. Headquartered in Dallas, other sites
include Carlsbad, Calif.

parkcrest standpoints

Hythiam Announces Licensing Agreement to Offer HANDS Protocols Through Ardent Health Services Facilities

"Ardent Health Services is a leader in dealing with
behavioral diseases and their expertise in this area, combined with
their commitment to comprehensive, innovative approaches to ending the
cycle of dependency , creates an ideal environment for incorporation of
our HANDS(TM) Protocols. The HANDS(TM) Protocols
also provide for a maintenance program that includes medications and
incentives for patients to continue with the recovery process through
individualized continuing care programs.hythiam. Disruption of this pathway in addiction
leads to impaired control over the important body functions of sleep ,
nervousness and thinking.
The hypothesis is that restoring the balance within this pathway is
analogous to resetting the circuit breakers, so that the pathway
functions normally and a patient who is in recovery stays sober, and
is able to have a relatively quick return to normal of their sleep and
anxiety levels, as well as their thinking patterns. These risk factors include, among
others , limited operating history and lack of statistically
significant formal research studies; difficulty in developing,
exploiting and protecting proprietary technologies; intense
competition and substantial regulation in the healthcare industry; and
additional risks factors as discussed in the reports filed by the
Company with the Securities and Exchange Commission, which are
available on its website at http://www.gov

sober parkcrest

About Hythiam, Inc. Urschel. I am looking forward to studying the HANDS
Protocols(TM) as a potential treatment option for the countless number
of people whose lives have been destroyed by this devastating
illness. In the meantime it
would offer a very potent option which could help a great number of
dependent individuals and their families have success in their
recovery.hythiam.sec.

sober parkcrest

"This agreement represents a milestone for Hythiam in that Ardent
Health Services is the first network of behavioral hospitals to
license the HANDS(TM) Protocols ," said Terren S. Additionally, the location of Ardent Health
Services facilities in rural and suburban environments greatly
enhances our reach in providing these protocols to diverse
communities., national Medical Director
for behavioral services at Ardent Health Services. Ardent currently operates 35
hospitals in 14 states, providing a full range of medical/surgical,
psychiatric and substance abuse services to patients ranging from
children to adults. Additionally, Hythiam
provides proprietary administrative services to assist physicians and
facilities with staff education, clinical services , marketing and
sales support, and outcomes tracking methodologies for data analysis. Of the many brain
reward pathways which methamphetamine affects, the Mesocortical
pathway within the Limbic system is a focus of the destructive forces
of methamphetamine molecules.

vanduo tomkins

is a healthcare services management company, focused
on delivering solutions for those suffering from alcoholism and
addiction .com

Forward-Looking Statements

Except for statements of historical fact, the matters discussed in
this press release are forward looking and made pursuant to the Safe
Harbor provisions of the Private Securities Litigation Reform Act of
1995.
The 30-patient open label study will be conducted on
treatment-seeking subjects who are currently methamphetamine
dependent. Changes in the neurochemistry of the brain
underlie the hallmarks of substance dependency, including craving,
tolerance, withdrawal symptoms and relapse. Hythiam researches, develops, licenses and
commercializes innovative physiological treatment protocols for
substance dependence.

beatitudes meth

D."
Dr.

counselers standpoints

Urschel
and specializes in the areas of chemical dependency (addiction);
general psychiatry; and general neurological disorders, including
Alzheimer's disease, Parkinson's disease, chronic pain, headaches and
epilepsy.

"Methamphetamine abuse has become a pervasive problem in our
country, as has been recently reported by numerous sources; however,
very few medical options exist for the treatment of methamphetamine
addiction," said Dr.
An imbalance between the inhibitory and excitatory activity in the
brain, such as occurs during substance withdrawal, can change activity
in the dopamine system, as well as in other neuronal circuits ,
triggering undesirable symptoms and behaviors. The Clinical Outcomes
Registry will be comprised of 15 sites nationwide where the HANDS
Protocols(TM) are currently offered or will be offered commercially in
the near future. Standard, validated outcome measure will be included
for the duration of the registry period, which is expected to last
approximately 24 months.

meth hetty

We believe that alteration in GABA(A)
function, caused or exacerbated by chronic substance abuse, may be
associated with anxiety , sleep and cognition disorders.

painkillers sobriety

Peizer, Hythiam's
Chairman and CEO.

Hythiam, Inc. Hythiam researches, develops, licenses and commercializes
innovative physiological treatment protocols.
(NASDAQ:HYTM), a healthcare services management company that delivers
to treatment providers proprietary administrative services and
physiological protocols designed to treat substance dependence,
announced today that renowned addiction expert and Board Certified
Psychiatrist Harold C.

About Hythiam , Inc. Additionally, Hythiam provides proprietary
administrative services to assist physicians and facilities with staff
education, marketing and sales support, and outcomes tracking for data
analysis .

vanduo counselers

"The serious consequences of methamphetamine addiction continue to
spread rapidly across all cultures, races and societies," Peizer
continued. "Acknowledged by experts as highly resistant to treatment,
its cascading effects cause significant and long-standing problems --
not only to the patient but to families and communities. Primary outcomes will measure:

Number of days abstinent from methamphetamine use following
discharge from the outpatient HANDS Protocols(TM) treatment

Change in scores for methamphetamine cravings

Results of urine drug screens performed at weekly intervals
during the 12-week evaluation period

In the event of patient relapse , number of days until first
methamphetamine use and/or other drug use following HANDS
treatment. Research Across
America has conducted over 1,000 clinical trials for more than 50
pharmaceutical companies, as well as most contract research
organizations and numerous biotech companies.

reachout counselers

Business Editors/Healthcare Editors

LOS ANGELES----

Leading Behavioral Hospital Network to
Deploy Protocols in Five Initial Sites

Hythiam, Inc.
"Hythiam is proud of its leadership role in developing an acute
medical intervention for methamphetamine dependency and is gratified
that Dr.
Additionally, he has published numerous articles on addiction
treatments (many as lead author) in a variety of journals and
textbooks , including Psychopharmacology Bulletin, Archives of General
Psychiatry and the DSM-IV Sourcebook .

painkillers steppin

The HANDS(TM) Protocols include medically
supervised procedures designed to target receptor sites in the brain
that regulate neurotransmitters implicated in brain processes of
substance dependency .

Business Editors/Health/Medical Writers

LOS ANGELES----Hythiam, Inc. Urschel, a highly -regarded addiction psychiatrist with a
strong background in research, is taking this opportunity to rapidly
provide the industry with data on a much needed physiological option
for treating this disease," said Terren S. "Hythiam seeks to build upon a solid foundation of clinical
evidence for HANDS(TM) and this will be the first of several research
studies that we anticipate will be initiated in ensuing months,
including both comparative as well as double-blind placebo-controlled
studies . Urschel continued, "Methamphetamine addiction is an extremely
destructive and devastating addiction for an ever-increasing number of
people in the US. Its vast network of
board-certified physician investigators and professional research
coordinators are experienced in all therapeutic areas.

painkillers silvan

For further information please visit www. Urschel, III, M. "This study has been designed in order
to rapidly accrue patients and provide clinical outcomes data into the
market as soon as possible. The CNS Group
at Research Across America specializes in clinical trials of
investigational and conventional medications for treating general
psychiatric, addiction and neurological disorders.

vanduo dysfunctional

Hythiam is a healthcare services management company focused on
delivering solutions for those suffering from alcoholism and other
substance dependencies.

sober dysfunctional

---

- - kjjkjk

Loading...

(Note: These pages use the Atlas Content Safeguard System (ACSS) and require that Javascript is enabled for viewing.)