S. 13%),
headache (8% vs . For children 6 months to 5 years of age, syrup
side effects varied by age and included fever, diarrhea , upper respiratory
infection, irritability and coughing.pdf. Allergy 2002; 57: 1048-52. adults aged 18
and older who have been diagnosed with seasonal allergies and are currently
using prescription allergy medication to treat their allergies. Weighting was based on age within gender,
education , race/ethnicity, region, income and propensity to be online. adults aged 18 and over who have been
diagnosed with seasonal allergies and are currently using prescription
allergy medication to treat their allergies.

(2) Patients who are not fully satisfied with their current prescription
allergy medication are defined as those who say they are somewhat or
not at all satisfied with their current prescription allergy
medication.

allergist pollen

The new treatment option addresses an important
need for allergy sufferers, who indicate that nasal congestion is the most
bothersome symptom of allergic rhinitis., member of AAFA's Medical-Scientific Council.

drgreene aafa

(3) There also is a growing body of evidence
that points to an association between allergies and more serious conditions,
such as asthma.

About Allergic Rhinitis
Allergic rhinitis, commonly referred to as hay fever or allergies, affects
as many as 50 million Americans each year.
This survey is made possible through an unrestricted educational grant
from Alcon Laboratories, Inc...

FOR MORE, VISIT AAFA.

anaphylaxis rxinsider

, Schering-Plough Corporation
(NYSE: SGP) today announced that the U. CLARINEX (2. CLARINEX
(0. For additional important safety
information, full prescribing information is available at:
http://www.spfiles. Sixty percent of allergy patients also agree(3)
they are very interested in finding a new prescription allergy medication. Among allergy
patients who are not fully satisfied(2) with their current prescription
allergy medication, more than half (55%) say they are not satisfied because
their allergy medication does not relieve their symptoms for a long enough
period of time, and nearly half (44%) are not satisfied because their allergy
medication does not provide symptom relief quickly enough.
"This can be a very costly, dangerous and frequently ineffective solution to
treating bothersome symptoms," added Dr.

Oral medications are the most commonly used form of prescription allergy
medication (67%); however, about four out of five allergy patients (81%) say
they would try a nasal spray to treat their allergy symptoms. adults 18 and older who
have been diagnosed with seasonal allergies and are currently using
prescription allergy medication. In
theory, with probability samples of this size, one can say with 95 percent
certainty that the overall results have a sampling error of +/- 4.

urticaria anaphylaxis

D.5 mg per 1 mL) Syrup, available in a bubblegum flavor , is approved for the
relief of symptoms of outdoor allergies in children 2 years and older, and
indoor allergies and hives of unknown cause in children as young as 6
months. The most commonly reported adverse events for
CLARINEX-D 24 HOUR Extended Release Tablets were dry mouth, headache,
insomnia , fatigue, sore throat and drowsiness. Through internal research
and collaborations with partners Schering-Plough discovers, develops,
manufactures and markets advanced drug therapies to meet important medical
needs. Schering-Plough does
not assume the obligation to update any forward-looking statements .

New Survey Suggests Patients Want Fast Long Relief of Allergy Symptoms

C. Patel.aafa.

rhinitis rxinsider

2%), somnolence
(3% vs.J.

ADDITIONAL RESOURCES: Audio version and more available at
http://www.

aafa rhinology


The most commonly reported adverse events for CLARINEX-D 12 HOUR Extended
Release Tablets compared with pseudoephedrine are insomnia (10% vs. CLARINEX(R) (5 mg) Tablets treat the
symptoms of seasonal and year-round allergies and hives of unknown cause in
patients 12 years of age and older.
"Patients are taking two, three, sometimes four different medications at a
time to relieve their symptoms quickly and effectively because they are
increasingly unsatisfied with their allergy medications ," said Alpen Patel,
MD, Assistant Professor in Otolaryngology, George Washington University
Medical Center, Washington, D.
Nearly half (47%) of allergy patients say they are taking multiple allergy
prescription medications and over one-third (36%) of allergy patients who take
prescription allergy medication also say they are using over-the-counter or
non-prescription allergy medications.
When it comes to choosing a new medication, many patients may be confused
by all the options.

Data are weighted to be representative of all U. This online sample is not a probability sample .
Allergens indoors such as dust mites, pet dander and mold can trigger the
violent sneezing, the runny eyes, the watery nose, and for people with asthma,
some symptoms can be even more severe .

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(5) CLARINEX-D(R) 24 HOUR (desloratadine 5 mg/ pseudoephedrine 240 mg)
Extended Release Tablets is a once-daily prescription antihistamine and
decongestant combination treatment which provides 24 -hour relief of nasal and
non-nasal symptoms of outdoor allergies in patients 12 years of age and
older. Syrup side effects in children 6 to 11 years of
age were similar to placebo.
Sampling error for the sub-samples of, patients who are somewhat or not at
all satisfied with their current prescription allergy medication (348),
patients who somewhat or strongly agree that they are interested in finding a
new prescription allergy medication (480), and patients who say they are
interested in switching to another prescription allergy medication (600) is
higher and varies. 248
angel@aafa.prnewswire.

The presence of this allergen in the body causes a series of chemical reactions in the immune system which result in individual signs

rhinology aafa

8%), fatigue (4% vs. For
further details about these or other factors that may impact the forward-
looking statements, see Schering -Plough's Securities and Exchange Commission
filings, including the company's third quarter 2005 10 -Q.

2.
- Fast-acting: Eighty-five percent of allergy patients believe it is
important prescription allergy medications work quickly to relieve
symptoms.S.
Allergies are not only bothersome, but many have been linked to a variety
of common and serious chronic respiratory illnesses (such as sinusitis and
asthma).S.com/broadcast/21183/consumer.

swelling allergies

FDA Approves CLARINEX-D(R ) 12 HOUR (desloratadine 2.5mg/pseudoephedrine 120mg) Tablet Prescription Antihistamine with Decongestant for Seasonal Allergy Suffere

Food and Drug Administration (FDA)
has approved CLARINEX-D(R) 12 HOUR (desloratadine 2."
The new formulation uses a bi-layer tablet delivery system, which controls
the release of the pseudoephedrine component for consistent delivery., chief medical officer and senior vice president,
Schering-Plough.
The company is based in Kenilworth, N.

6. (Eighty-three percent of allergy patients consider quick
allergy symptom relief to be within 30 minutes. "The survey findings suggest the
need for patients to have open dialogues with their doctors about the allergy
medications they are taking and available treatment options out there.
AAFA
provides free information to the public, offers educational programs to
consumers and health professionals, leads advocacy efforts to improve patient
care and supports research to find cures .

The allergen is the specific protein substance that a person is allergic to.

anaphylaxis wheezing

Spiegel, M. In both 2-week randomized,
parallel group trials, the antihistaminic efficacy of CLARINEX-D 12 HOUR, when
examining symptoms of allergic rhinitis excluding nasal congestion, was
significantly greater than that of pseudoephedrine alone during the treatment
period.
CLARINEX-D 12 HOUR Extended Release Tablets should be administered when
the antihistaminic properties of desloratadine and the nasal decongestant
properties of pseudoephedrine are desired. Roper Public Affairs and Media. Patel . Allergies reflect an overreaction
of the immune system to substances that usually cause no reaction in most
individuals, such as pollens, mold, dust or animal dander. Treatment can include
avoidance of allergens, medication options and/or immunotherapy (allergy
shots).

ridding anaphylaxis

, Allergy + Asthma
Specialists , Dallas, Texas. 2%), and pharyngitis (3% vs. The American Academy of Allergy, Asthma + Immunology, Inc .

7. CLARINEX-D(R) 12 HOUR Product Information.
Symptom relief may be among the top factors contributing to patient
dissatisfaction with prescription allergy medication, according to the survey
of 1,214 allergy patients conducted by Harris Interactive(R).)
- Steroid-free: About half of allergy patients (51%) believe it is
important for allergy medications to be steroid-free..

niaid njc


"Physicians now have a 12-hour formulation that combines the proven
efficacy and safety of CLARINEX with an established decongestant," said Robert
J."
The FDA approved CLARINEX-D 12 HOUR based on results from two clinical
trials involving 1,248 patients 12 to 78 years of age with seasonal allergic
rhinitis, 414 of whom received CLARINEX-D 12 HOUR.
Symptoms, which include sneezing, runny nose, congestion, itchy throat, or
itchy and watery eyes, can have a significant impact on everyday activities at
work, school and leisure time.

References:
1.
Roper Public Affairs and Media.

4.

SPRING FEVER ISN'T JUST A MYTH.

medfacts drgreene

The
recommended twice-daily dosing of CLARINEX-D 12 HOUR will help patients
control their nasal congestion, along with their sneezing, runny nose, itchy
throat, or itchy and watery eyes, in the morning and throughout the day. "CLARINEX-D 12 HOUR provides physicians with another option
for tailoring allergy treatment regimens based on patients' specific symptoms
and needs. As the data show, CLARINEX-D 12 HOUR effectively
treats nasal congestion, the most bothersome symptom of allergic rhinitis, in
addition to relieving other nasal and non-nasal symptoms of allergic rhinitis. 3%).5 orally-disintegrating
tablets) RediTabs (R) tablets treat the symptoms of seasonal and year-round
allergies and hives of unknown cause in patients 6 years of age and older; a
5mg RediTabs tablet is available for patients 12 years and older .(5)
Due to its pseudoephedrine component, CLARINEX-D 12 HOUR Extended Release
Tablets and CLARINEX-D 24 HOUR Extended Release Tablets should not be taken by
patients with narrow-angle glaucoma (abnormally high eye pressure), difficulty
urinating, severe high blood pressure, or severe heart disease, or by patients
who have taken a monoamine oxidase (MAO) inhibitor within the past 14 days . Care should be used if CLARINEX-D 12 HOUR Extended Release
Tablets or CLARINEX-D 24 HOUR Extended Release Tablets are taken with other
antihistamines or decongestants because combined effects on the cardiovascular
system may be harmful. Schering Corporation.shtml

AUDIO PROVIDED BY: Asthma and Allergy Foundation of America


rhinology sinusitis

(1) In addition, a survey of 1,000
adults with allergic rhinitis found nearly 85 percent experience nasal
congestion when they first wake up, making it the most prevalent allergy
symptom in the morning.


About half (51%) of those who say they are interested in
switching to another prescription allergy medication agree(4) they are
confused by all of the different options available today, and six out of 10
patients (59%) agree they wish they knew more about the different types of
prescription allergy medications available .
"Nearly 30 percent of patients admit they don't even know what type of
allergy medication they are taking, whether it is an antihistamine or an anti-
inflammatory steroid drug," said Dr.
S.

(3) Agree is defined as somewhat or strongly agree. MORE THAN FIFTY MILLION AMERICANS SUFFER
FROM ALLERGIES THIS TIME OF YEAR.ORG.

persistant rxinsider

New Formulation Provides Powerful Relief Of Seasonal Allergy Symptoms,
Including Nasal Congestion

KENILWORTH, N. 9%), dry mouth (8% vs.S.com/piclarinex.

About Schering-Plough Corporation
Schering-Plough is a global science-based health care company with leading
prescription, consumer and animal health products. Schering Corporation.
While showing the desire among a majority of allergy patients for new
prescription allergy treatments, the survey also reveals what patients
consider to be important aspects of an allergy prescription medication,
including:

- Long-lasting: Eighty -eight percent of allergy patients believe it is
important for prescription allergy medications to provide long-lasting
relief of symptoms.
Appropriate allergy treatment is based on the results of allergy tests,
medical history and the severity of your symptoms.

wheezing swelling



About Allergies
Seasonal allergies affect an estimated 36 million people in the U. Impact of nasal congestion among
allergic rhinitis sufferers, 2004.3 percentage
points. To learn more about AAFA, visit
http://www. I'M DANIELLE ADDAIR.

urticaria aafa

J., and its Web site is
http://www.

3. Linneberg A, Henrik Nielsen N, Frolund L, et al. The link between
allergic rhinitis and allergic asthma: a prospective population-based
study.

5.

"It's very hard to ignore outdoor allergies this time of year with all the
tree pollen, but people head indoors and that can be a problem, too . "

EXPERTS RECOMMEND RUNNING THE AIR CONDITIONING DURING HUMID MONTHS,
VACUUMING REGULARLY WITH A HEPA OR DOUBLE-BAG VACUUM AND USING CLEANING
SOLUTIONS CONTAINING LOW CONCENTRATIONS OF BLEACH LIKE THE LEVELS FOUND IN
TILEX(R) MOLD AND MILDEW REMOVER WHICH EFFECTIVELY KILLS THE MOLD SPORES
NEUTRALIZING THE MOLD ALLERGEN.

medfacts conjunctivitis

Tablet side effects in patients 12 years of
age and older with ongoing itching and rash from hives of unknown cause were
headache , nausea and fatigue.com for more information on preventing and
treating seasonal nasal allergies ."

Survey Methodology
Harris Interactive conducted the online survey on behalf of AAFA from
October 10 to 17, 2005, among a national sample of 1,214 U.

About AAFA
The Asthma and Allergy Foundation of America (AAFA) is the premiere non-
profit patient organization fighting asthma and allergic diseases.org..

An allergy is a sensitivity to a certain substance which , in similar quantity, is tolerated by non-allergic people.

conjunctivitis njc


CLARINEX-D 12 HOUR will be available nationwide in March 2006, in time for
the spring allergy season.(6,7)
Visit http://www. Many
factors could cause actual results to differ materially from Schering-Plough's
forward-looking statements, including market forces, economic factors, product
availability, current and future branded , generic or over-the-counter
competition and the regulatory process, among other uncertainties.org

(1) Allergy patients defined as U.

Experts Offer Solutions In Time for Spring Allergy Season !

NEW YORK,

THIS IS A MULTIVU SPECIAL REPORT.

allergies allergen

5 mg and pseudoephedrine
sulfate, USP 120 mg) Extended Release Tablets for the relief of nasal and non-
nasal symptoms of seasonal allergic rhinitis (outdoor allergies), including
nasal congestion, in patients 12 years of age and older.
CLARINEX. Schering-Plough's vision is to earn the trust of the physicians,
patients and customers served by its more than 30,000 people around the world.com.

SCHERING-PLOUGH DISCLOSURE NOTICE: The information in this press release
includes certain "forward-looking statements" within the meaning of the
Securities Litigation Reform Act of 1995, including statements related to
CLARINEX and the potential market for CLARINEX. These substances
can trigger sneezing, itchy, watery eyes, nasal congestion, runny nose, itchy
nose, throat and palate and sinus headaches.

allergist persistant

"With CLARINEX-D 12 or 24 hour extended release
tablets, I can now prescribe a 12- or 24-hour formulation that does not cause
drowsiness and treats their nasal blockage effectively.(4)

About the CLARINEX Family of Products
CLARINEX is the only branded prescription allergy treatment available in
this diverse variety of formulations.schering-plough. Assessment of morning allergy suffering
among adults with allergies, 2005. CLARINEX(R) Tablets, Syrup and RediTabs Product Information.Six out of 10 allergy patients indicate interest in finding a new prescription
medication

WASHINGTON, Nearly one-third of allergy
patients(1) (31%) are not fully satisfied(2) with their current prescription
allergy medication, according to a new survey from the Asthma and Allergy
Foundation of America (AAFA). Additionally, allergic reactions can be severe and even fatal.
However, with proper management and patient education, allergic diseases can
be controlled, and people with allergies can lead normal and productive lives.

CONTACTS: Jennifer Corrigan Angel Waldron
732-382-8898 202-466 -7643 ext. MIKE TRINGALE OF THE ASTHMA AND ALLERGY
FOUNDATION OF AMERICA CAUTIONS ALLERGY SUFFERERS .

EXPERTS CAUTION THAT ALL BLEACH-BASED CLEANERS SHOULD BE EPA REGISTERED
AND THAT ALLERGY AND ASTHMA SUFFERERS SHOULD ASK UNAFFECTED PEOPLE TO APPLY
ALL CLEANING PRODUCTS.

urticaria allergies

(2)
"For my patients who report nasal congestion along with other allergy
symptoms, an antihistamine and decongestant combination treatment provides
safe and effective relief," said William Lumry, M. And the decongestant efficacy of CLARINEX-D 12 HOUR was significantly
greater than that of desloratadine alone during the treatment period, based on
nasal congestion scores.(6)
CLARINEX Tablet side effects in patients 12 years of age and older with
seasonal and year-round allergies were similar to placebo and included sore
throat, dry mouth and fatigue.

rxinsider drgreene

Forward-looking statements
relate to expectations or forecasts of future events.

niaid njc

D.
Patients with high blood pressure; diabetes; heart disease; increased
intraocular pressure (eye pressure); thyroid, liver or kidney problems; or
enlarged prostate should check with their health care provider before taking
CLARINEX-D 12 HOUR Extended Release Tablets or CLARINEX-D 24 HOUR Extended
Release Tablets., The Allergy
Report, 2000. The Copenhagen Allergy Study,. Schering
Corporation. CLARINEX-D(R) 24 HOUR Product Information.

(4) Agree is defined as somewhat or strongly agree.


medfacts ridding

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