Significantly
expanding the previous edition, the current book contains 70 chapters ., Senior Vice President of Joslin's
Strategic Initiatives Division, Director of Behavioral and Mental Health, and
HMS Professor of Psychiatry., former Chief Medical Officer at
Joslin and HMS Professor of Medicine; and Robert J.org or by calling toll-
free (within the U.gif

Contact:
Marge Dwyer or Jenny Eriksen, Joslin Communications, (617) 732-2415
Marjorie.
Dr .

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"
Tailored to primary care and specialty practitioners, the 1,209-page book,
published by Lippincott Williams + Wilkins of Philadelphia, harnesses the
expertise of more than 125 diabetes authorities worldwide.S. Approximately 1 million people in the U.harvard.

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14th Edition Tailored to Primary Care and Specialty Practitioners

BOSTON, Joslin Diabetes Center, the world's leading
authority in diabetes research, care and education, has published the
fourteenth edition of Joslin Diabetes Mellitus, providing the medical
profession with valuable new insights on diabetes research and treatments.
Joslin, M.
* The role of fat cells--once considered dormant storage sites--which is
thought to include secretion of a protein that regulates body tissues,
such as brain cells and blood vessels.
* Further insight into how high glucose levels cause eye and kidney
damage, leading to possible ways to prevent these complications.

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Over 41 million Americans are believed
to have pre-diabetes, or risk factors that will lead to type 2 diabetes if
left untreated.joslin., Researchers in Sweden have
discovered that growth hormone (GH) treatment may result in the reduction of
multiple metabolic disorders associated with abdominal obesity in
postmenopausal women.

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* An additional role for islet cells, which, in addition to secreting
insulin, produce proteins that enhance insulin activity--a discovery
that may lead to new drugs for treating diabetes.

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Joslin's New Textbook is Leading Source for Advances in Diabetes Care

"The results of our study suggest that
growth hormone treatment has a favorable effect on multiple metabolic
disorders associated with abdominal obesity in postmenopausal women .

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With the first 5,000 copies selling in less than two months, the book is now
in its second printing -- demonstrating an enthusiastic market for this
comprehensive guide. Weir, M.
"The textbook covers a wide spectrum of topics, ranging from the basic
mechanisms of islet development and function , hormone action and regulation of
metabolism, to the epidemiology and genetics of diabetes, the role of obesity,
insulin therapy and oral agents, diabetes in minorities, nutrition and
exercise, and the behavioral and psychological issues related to diabetes,"
said Editor Alan M. As a nonprofit , Joslin
benefits from the generosity of donors in advancing its mission.edu
Jenny.

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D. King , M.
* Emerging new classes of drugs to treat type 2 diabetes, such as
medications that target a nuclear molecule called PPAR-gamma, which
promotes insulin sensitivity. Smith , M. at 1-508-583-3240.S.

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Ronald Kahn, M.
Beginning with the history of diabetes and the pioneering work of Elliott P.harvard.

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,
President and Director of Joslin Diabetes Center, the Mary K. Iacocca
Professor of Medicine at Harvard Medical School (HMS) and one of the book's
six senior editors.

About Diabetes
An estimated 18 million Americans have type 2 diabetes; about one-third of
those don't even know they have it.

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D.D. Joslin research is a team of more than 300 people at
the forefront of discovery aimed at preventing and curing diabetes.

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store. Published today in the March issue of The Journal of
Clinical Endocrinology + Metabolism, these findings demonstrate the important
role growth hormone treatment may play in reducing serious metabolic
conditions , such as diabetes and heart disease.

JCE+M is one of four journals published by The Endocrine Society.

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Type 2 diabetes, traditionally considered
a disease of middle-aged and older adults, is occurring more frequently in
younger people due to increasing obesity and sedentary lifestyle.org . A previous trial of GH
treatment in men with abdominal obesity demonstrated reduction in abdominal
fat mass and beneficial effects on insulin sensitivity and lipids.
The team discovered that the GH treatment in postmenopausal women
significantly reduced their intra-abdominal fat, increased thigh muscle area,
reduced low-density lipoprotein (LDL) cholesterol concentration, and improved
insulin sensitivity. Together, these members represent all
basic, applied, and clinical interests in endocrinology.

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I.org/images/Publications/diabetesmel_14th. CHEVY CHASE, Md."
This information may offer a treatment option for doctors who treat
postmenopausal women and may reduce the metabolic consequences associated with
intra-abdominal fat accumulation. Endocrinologists are specially trained doctors who diagnose,
treat and conduct basic and clinical research on complex hormonal disorders
such as diabetes, thyroid disease, osteoporosis, obesity, hypertension,
cholesterol and reproductive disorders. Today, The Endocrine Society's
membership consists of over 12,000 scientists, physicians , educators, nurses
and students, in more than 80 countries. The Endocrine Society
is based in Chevy Chase, Maryland. To learn more about the Society, and the
field of endocrinology, visit the Society's web site at
http://www.

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D.
* Promising new treatments for type 1 diabetes, including transplantation
of islet cells. For more
information on Joslin, call 1-800-JOSLIN-1 or visit http://www.

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In addition to serving as a comprehensive overview for endocrinologists
and diabetes specialists, the new Joslin textbook is an important tool for
primary care physicians, nurses and educators. Jacobson, M.S.) 1-800-344-4501 or outside the U. have type 1
diabetes, which is associated with the body's failure to produce insulin, a
hormone necessary for the body to convert glucose into energy.

Note to editors: A photo of the cover of the fourteenth edition of Joslin
Diabetes Mellitus, can be downloaded from the following link:
https://store. The placebo group did not experience these positive
results.

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Moses, M.

About Joslin Diabetes Center
Joslin Diabetes Center, dedicated to conquering diabetes in all of its
forms, is the global leader in diabetes research , care and education.edu

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"Dramatic advances in the laboratory and the clinic are revolutionizing
our understanding and the care of diabetes ," said C., founder of Joslin Diabetes Center, the father of modern day
diabetes care and author of the first edition (published in 1916), the new
textbook contains eight main sections, each designed to help healthcare
practitioners and researchers solidify their understanding of diabetes and
treatment of the disease."
"Many of the advances in the research lab have been translated into the
clinical practices outlined in this book," said Joslin Diabetes Mellitus
Editor George L.D.

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The fourteenth edition of Joslin Diabetes Mellitus can be purchased online
through the Joslin Store at https://www .joslin.joslin.dwyer@joslin.

Growth Hormone Treatment Improves Symptoms of Metabolic Disorder in Postmenopausal Women

Many
postmenopausal women experience a natural increase in obesity, particularly an
increase of intra-abdominal fat, which refers to fat that is stored in and
around the internal organs. Johansson .endo-society.org.

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, Director of Research, Head of the Section on
Vascular Cell Biology at Joslin and HMS Professor of Medicine.D.

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"It's critical for both researchers and healthcare
professionals to keep pace, particularly as diabetes is growing at epidemic
proportions and research advances are coming quickly., Head of Joslin's Section on
Islet Transplantation and Cell Biology and HMS Professor of Medicine.

Other editors include Alan C.D., Director of
Medicine at the Hallett Center for Diabetes and Endocrinology, Professor of
Medicine at Brown Medical School, Providence, R. Diabetes can
lead to many serious complications, including heart disease, stroke, nerve
damage, kidney failure and blindness.

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"With millions of people with
diabetes or at risk for developing the disease , primary caregivers are a
critical part of the healthcare team, and this book provides them with an
excellent tool," said Editor Gordon C. "The
more primary caregivers know about diabetes, the more they can do for their
patients. Founded
in 1898, Joslin is an independent nonprofit institution affiliated with
Harvard Medical School. Joslin
Clinic, affiliated with Beth Israel Deaconess Medical Center in Boston, the
nationwide network of Joslin Affiliated Programs, and the hundreds of Joslin
educational programs offered each year for clinicians, researchers and
patients, enable Joslin to develop, implement and share innovations that
immeasurably improve the lives of people with diabetes .
Typically, GH is known for its importance in the growth of a child, but it
also has powerful metabolic effects in adults. Gudmundur Johannsson and his research team at the Sahlgrenska
University Hospital in Sweden investigated the effect of GH treatment for one
year on insulin sensitivity in postmenopausal women with abdominal adiposity.
They also studied the effects of the hormone on abdominal fat, hepatic fat
content and size of the thigh muscle area. Founded
in 1916, The Endocrine Society is the world's oldest, largest, and most active
organization devoted to research on hormones, and the clinical practice of
endocrinology.

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Insulin is
required treatment for people with type 1.

eriksen@joslin.

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"Previous research has shown that obesity is linked to metabolic syndrome,
which has several known risk factors including high cholesterol, high blood
pressure, increased levels of fasting glucose and an increase in waist
circumference," explains Dr.

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Included in the textbook are the following recent findings regarding the
basic science of diabetes and its clinical care:
* The biology of insulin function, including how it stimulates events
inside cells to produce energy.