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population, providing us with an extensive
customer base for our current and future products. The Company has
commercialized Analyte Specific Reagents(x) and a series of Tag-It(TM)
tests(xx) for a variety of genetic disorders.

Growth Hormone Treatment Improves Symptoms of Metabolic Disorder in Postmenopausal Women

"The results of our study suggest that
growth hormone treatment has a favorable effect on multiple metabolic
disorders associated with abdominal obesity in postmenopausal women.

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Tm Bioscience to supply LabCorp with Tag-It(TM) products

Analytical and performance characteristics
are not established. The performance characteristics of
these products have not been established

About Tm Bioscience - Putting the Human Genome to Work(TM)
Tm Bioscience is a DNA -based diagnostics company developing a suite of
genetic tests.

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The placebo group did not experience these positive
results.

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, Researchers in Sweden have
discovered that growth hormone (GH) treatment may result in the reduction of
multiple metabolic disorders associated with abdominal obesity in
postmenopausal women.

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About Tag-It(TM) reagents and genetic tests
Tm Bioscience's product menu is focused in the fields of human genetic
disorders, pharmacogenetics and infectious disease.
They also studied the effects of the hormone on abdominal fat, hepatic fat
content and size of the thigh muscle area. Founded
in 1916, The Endocrine Society is the world's oldest, largest, and most active
organization devoted to research on hormones, and the clinical practice of
endocrinology.endo-society.

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and now one of our largest customers," said Greg Hines, President and CEO
of Tm Bioscience. Tm Bioscience is located
in Toronto, Ontario.

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S.

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TSX: TMC

TORONTO, June 28 - Tm Bioscience Corporation
(Toronto, Ontario; TSX: TMC), a leader in the commercial genetic testing
market, today announced it has signed a master purchase agreement to supply
Laboratory Corporation of America(R) Holdings (LabCorp(R); NYSE: LH) with a
suite of Tag-It(TM) products.S.
The Company's Tag-It(TM) Cystic
Fibrosis (CF) Kit is the first multiplexed human disease genotyping test to be
cleared by the U. CHEVY CHASE, Md. A previous trial of GH
treatment in men with abdominal obesity demonstrated reduction in abdominal
fat mass and beneficial effects on insulin sensitivity and lipids. Gudmundur Johannsson and his research team at the Sahlgrenska
University Hospital in Sweden investigated the effect of GH treatment for one
year on insulin sensitivity in postmenopausal women with abdominal adiposity.
"Previous research has shown that obesity is linked to metabolic syndrome,
which has several known risk factors including high cholesterol, high blood
pressure, increased levels of fasting glucose and an increase in waist
circumference," explains Dr. Endocrinologists are specially trained doctors who diagnose,
treat and conduct basic and clinical research on complex hormonal disorders
such as diabetes, thyroid disease, osteoporosis, obesity, hypertension,
cholesterol and reproductive disorders.

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S.
Typically, GH is known for its importance in the growth of a child, but it
also has powerful metabolic effects in adults.

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"LabCorp is one of the foremost providers of diagnostic testing in the
U.tmbioscience.

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(xx) For Investigational Use Only. Today, The Endocrine Society's
membership consists of over 12,000 scientists, physicians , educators, nurses
and students, in more than 80 countries.

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To learn more about the Society, and the
field of endocrinology, visit the Society's web site at
http://www.

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Published today in the March issue of The Journal of
Clinical Endocrinology + Metabolism, these findings demonstrate the important
role growth hormone treatment may play in reducing serious metabolic
conditions, such as diabetes and heart disease.
Dr.

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"
The first products covered under the agreement are Tag-It(TM) ASR(x)
reagents for use in LabCorp's Ashkenazi Jewish Panel (AJP) gene assay, a
single genetic test that combines mutation detection for eight disease states
into one assay. Combined, the
Universal Array and Luminex instrument enable the rapid production of
flexible, high-throughput , low-cost DNA-based tests.

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Food and Drug Administration (FDA) as an in vitro device
(IVD) for diagnostic use in the United States. Assays from Tm operate on the Luminex
xMAP(R) system, a well-established bead based instrument.

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Tm Bioscience's product pipeline includes tests for genetic
disorders, drug metabolism, and infectious diseases.

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(x) Analyte Specific Reagent. Many
postmenopausal women experience a natural increase in obesity, particularly an
increase of intra-abdominal fat, which refers to fat that is stored in and
around the internal organs."
This information may offer a treatment option for doctors who treat
postmenopausal women and may reduce the metabolic consequences associated with
intra-abdominal fat accumulation.

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"With this supply agreement, our commercial footprint
reaches the majority of the U. All genetic tests from Tm
Bioscience are based on the Tag-It(TM) Universal Array platform, which
utilizes a proprietary universal tag system that allows for easy optimization,
product development and expansion. Together, these members represent all
basic , applied, and clinical interests in endocrinology.org.

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The Endocrine Society
is based in Chevy Chase , Maryland.

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We are delighted to begin
supplying LabCorp and look forward to working with them as they launch
additional Tag-It(TM) products. The AJP assay detects gene mutations associated with Tay-Sachs
disease, Canavan Disease, Familial Dysautonomia, Gaucher Disease, Bloom
Syndrome, Fanconi Anemia , Neimann-Pick Disease, and Mucolipidosis Type IV. Additional information about Tm Bioscience can be found
at http://www. Johansson.

JCE+M is one of four journals published by The Endocrine Society.

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com.
The team discovered that the GH treatment in postmenopausal women
significantly reduced their intra-abdominal fat, increased thigh muscle area,
reduced low-density lipoprotein (LDL) cholesterol concentration, and improved
insulin sensitivity.


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