William
Netzer, PhD is a principal member of the
Greengard Lab at Rockefeller University in New York City
. These studies were sponsored in part by Geron
Corporation.D.
authority nutrition
D., Geron's
president and chief executive
officer.aging gerontologists
walford findings
"The fact that Parkinson's Disease can strike one of the world's most
brilliant and
inspirational leaders shows that no one is immune to this
dreaded disease.ph specialties
Paul Greengard,
the
labs director, won the 2000 Nobel Prize in Medicine for his discoveries of
the mechanisms of nerve
cell communication and their relevance to Parkinson's
disease.----Geron
Corporation (Nasdaq:GERN
) announced today the publication of studies
demonstrating that hematopoietic stem cells (HSCs) derived
from human
embryonic stem cells (hESCs) can establish hematopoiesis in mouse
models, leading to
production of all major human blood cell types.walford gerontological
"Dr.
Employing the principles of hematopoietic chimerism
, hESC-derived HSCs
and the therapeutic cells would be differentiated from the same hESC
line.
understandings aging
Discussions of the latest research will help the public better understand
the Pope's condition
and the difficulties known to be associated with
Parkinson's disease.
For more information
please visit: http://www.senescence ph
aging geriatrics
"
The successful establishment of hematopoiesis in vivo by
hESC-derived
HSCs has a positive implication for inducing acceptance
of therapeutic grafts without need for long
-term immunosuppression.
extension recommendations
The Foundation supports worldwide research into the cause and
cure of
Parkinson's Disease through its Program in Molecular and Cellular Neuroscience
at The
Rockefeller University in New York City.alzinfo.
Actual results may differ materially from the results
anticipated in
these forward-looking statements.preparing geriatrics
Progress is being made in our efforts to understand
this
disease and help those who suffer from its debilitating effects.
This news release may
contain forward-looking statements made
pursuant to the "safe harbor" provisions of the Private Securities
Litigation Reform Act of 1995.preparing nutrition
The Michael Stern Parkinson's Research Foundation is a not
-for-profit
corporation established exclusively for scientific and educational purposes.
"This
work provides strong evidence that functional hematopoietic
stem cells can be derived from human
embryonic stem cells," stated
Jane S.further leonid
Lebkowski, Ph.aging further
Dr.ph preparing
NEW YORK, Due to the passing of his
holiness Pope
John Paul II of Parkinson's disease, The Michael Stern Parkinson's Research
Foundation
wishes to call attention to its current research efforts aimed at
discovering treatments for Parkinson
's and eventually a cure.authority geriatrics
One of the
Foundation's scientists, William Netzer PhD, will be made available
for
interviews." said Dr.
Greengard. When transplanted into immune deficient
mice, the hESC
-derived HSCs survive and establish multi-lineage
hematopoiesis-producing human lymphocytes, red blood
cells, and
myeloid cells.gerontology gerontologists
Mickie Bhatia and his colleagues from the Krembil Center for
Stem Cell
Biology and Regenerative Medicine at the Robarts Research
Institute in London, Ontario, Canada have
now published studies in the
May issue of the Journal of Experimental Medicine showing that hESCs
can be differentiated into HSCs, the cells which produce all of the
cellular components of blood
.
"We are particularly excited by the developments described in this
publication, especially considering
the difficulties scientists have
had in the past establishing hematopoietic engraftment from mouse
embryonic stem cells," stated Thomas B.gerontological gavrilov
The Latest Research Explained by Leading Scientist and The
Pope's Battle With Parkinson's
Dr.gavrilov longevity
These results document the potential of differentiated
hESCs to
survive and establish functional tissue in vivo and have positive
implications for strategies
to promote therapeutic graft acceptance
without use of long-term immunosuppression.aging gerontologists
parkinsoninfo
.org
Business Editors/Health Editors/Science Editors
MENLO PARK, Calif. Okarma
, Ph.walford extension
Administration of the hESC-derived HSCs may allow "education" of
the recipient's immune system
to accept the therapeutic graft without
rejection."
Geron is a biopharmaceutical company developing
and
commercializing three groups of products: i) therapeutic products for
oncology that target
telomerase; ii) pharmaceuticals that activate
telomerase in tissues impacted by senescence, injury
or degenerative
disease; and iii) cell-based therapies derived from its human
embryonic stem cell
platform for applications in multiple chronic
diseases.walford geriatrics
The Michael Stern Parkinson's
Research
Foundation is the sister organization of the Fisher Center for
Alzheimer's Research Foundation (http:
//www.org ) whose operations support a
global network of research scientists with a focus on the cause
, care and cure
of Alzheimer's disease.D. Bhatia's studies have also elucidated
several key differences
between hematopoietic stem cell populations
derived from human embryonic stem cells versus cord blood
, providing a
series of benchmarks to enable the optimized production of
hESC-derived hematopoietic
cells., M. "We are continuing to develop
hematopoietic chimerism approaches as one means to limit
the need for
long-term immunosuppression for human embryonic stem cell-derived
grafts. Investors
are cautioned that such
forward-looking statements in this press release regarding potential
applications
of Geron's technologies constitute forward-looking
statements that involve risks and uncertainties
, including, without
limitation, risks inherent in the development and commercialization of
potential
products, need for future capital, reliance on
collaborators, and maintenance of our intellectual
property rights.findings geriatrics
, Geron's senior vice president of
regenerative medicine.grimshaw walford
Additional information
on potential
factors that could affect our results and other risks and
uncertainties are detailed
from time to time in Geron's periodic
reports, including the quarterly report on Form 10-Q for the
quarter
ended March 31, 2005.specialties understandings
Geron Announces Publication of Studies Demonstrating Hematopoietic Stem
Cells Differentiated From Human Embryonic Stem Cells Engraft and Establish Hematopoiesi
gerontologists gerontology
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