" The
book includes diagrams that realistically illustrate the damage done by the
radical prostatectomy. Twenty-seven illustrations and cartoons are
included within the book, which also includes an extensive index.SurvivingProstateCancerWithoutSurgery .
Dr.
The continued successful development of PT-141 is one of the highest
priorities of our research and development team and is progressing as
planned.S.

dysfunctions erection

These missing structures can no longer nourish the penis and it
atrophies.95, a trade
paperback, 334 pages, 34 chapters, ISBN Number: 0-9717454-1-2, and was
published January 15, 2005. Michael King Jolly, Executive Vice President , Research and Development
of King, stated, "Together with our colleagues at Palatin, we are excited to
begin this important next step in the clinical development program for PT-141.S.
4 CEDAR BROOK DRIVE, CRANBURY, NEW JERSEY 08512

foreskin inability

ROSEVILLE, Ill. The animal model showed that when the cavernous nerve branches are
cut, softer, smaller erections occur even with chemically-induced erections. One study suggests that the erectile tissue in the penis actually
dies off after the radical prostatectomy.EpididymitisFoundation.
See the web site: http://www.
Current literature indicates that about one half of all patients who receive
an initial prescription for a PDE-5 inhibitor do not renew the prescription
due chiefly to adverse side effects, drug interaction issues, and/or the lack
of an acceptable level of responsiveness.
501 FIFTH STREET, BRISTOL, TENNESSEE 37620


PALATIN TECHNOLOGIES, INC.

premature phimosis

Interested men should read the chapter inside "Surviving Prostate Cancer
Without Surgery" entitled: "The Radical Prostatectomy and Your Penis. "In addition, nerve
branches, arteries, and veins in the pelvis are always severed by the radical
prostatectomy.org ), and founded
the Acoustic Neuroma Foundation ( http://www."
"Surviving Prostate Cancer Without Surgery" can be found in fine
bookstores . After
receiving PT-141, some patients have experienced prolonged erections lasting
over 4 hours .

About Palatin
Palatin Technologies, Inc. Palatin's
strategy is to develop products and then form marketing collaborations with
industry leaders in order to maximize their commercial potential.

prepuce penetrate

"
"An animal model study [Chan et al. Biblio Distribution (800-462-6420) and Roseville Books/Rayve
Productions (888-492-2665) distribute the book.
The Company's internal research and development capabilities, anchored by its
proprietary MIDAS(TM) technology, are fueling product development . Food and Drug Administration's ("FDA")
review of Investigational New Drug Applications ("IND"), New Drug Applications
("NDA"), and supplemental New Drug Applications, ("sNDA") and/or the review of
other regulatory agencies worldwide; dependence on compliance with FDA and
other government regulations that relate to King's and Palatin's respective
businesses; dependence on King's and Palatin 's abilities to successfully
manufacture PT-141; and dependence on changes in general economic and business
conditions; changes in current pricing levels; changes in federal and state
laws and regulations; changes in competition; unexpected changes in
technologies and technological advances; and manufacturing capacity
constraints.

ED IS CURABLE in almost all cases.

attendant erectile

] there was a decrease in all penile
dimensions, even after 'nerve-sparing' radical prostatectomy," says Dr."
Why does the radical prostatectomy damage the penis so much? "The
operation removes the prostate and seminal vesicles and removing these
structures leaves a gap that is sometimes filled by pulling the penis up into
the body, effectively shortening it," says Dr. PT-141 is a
melanocortin agonist that King and Palatin are jointly developing for the
treatment of male and female sexual dysfunction .
Although the current ED market is primarily served by PDE-5 inhibitors
which target the vascular system, a substantial unmet medical need for
alternative sexual dysfunction therapies exists.

dysfunction foreskin

Men Suffer Smaller Penises after Prostate Cancer Surgery -- According to New Book

" The Savoie study found significantly smaller
penises in 124 men after prostate cancer surgery.
The first Phase IIb clinical trial will evaluate the safety and efficacy
of PT-141 in 560 non-diabetic patients suffering from mild to severe ED.

In extreme cases, this can result in an inability to penetrate even though an erection is present, and the erection can be very painful.

intercourse inability

AcousticNeuromaFoundation.

About PT-141
PT-141 is the first compound in a new drug class called melanocortin
receptor agonists under development to treat sexual dysfunction. Clinical data indicates that PT-141 may be effective in
treating a broad range of patients suffering from ED. Some side effects that
research participants have experienced include facial flushing, nausea, bad
taste, post-nasal drip and runny nose, headache , and vomiting.

curable retracted

This can cause painful erections and attendant impotence.

uncircumcised retracted

The book reveals other side effects suffered after the radical
prostatectomy including: loss of sensation to the penis, a cold penis, or a
penis that feels shriveled as if coming out of a cold swimming pool."
The non-diabetic Phase IIb clinical trial is scheduled to conclude in
mid-2006, while the conclusion of the diabetic Phase IIb clinical is scheduled
to follow in the second half of 2006.

EXECUTIVE OFFICES

KING PHARMACEUTICALS, INC .

Three other conditions can cause an inability to complete sexual union:

Peyronie's Disease, in which scar tissue or plaque forms on the shaft of the penis causing it to bend at an acute angle.

There are many treatment options in existence, and many more are under development.

foreskin premature

Hennenfent .

Both clinical trials will involve an "at home" three-month treatment period
conducted at approximately 35 clinical trial sites throughout the United
States.

About ED
ED is defined as the consistent inability to attain and maintain an
erection sufficient for sexual intercourse.

About King Pharmaceuticals
King, headquartered in Bristol, Tennessee , is a vertically integrated
branded pharmaceutical company.

Forward-looking Statements
This release contains forward-looking statements within the meaning of
Section 27A of the Securities Act of 1933, Section 21E of the Securities
Exchange Act of 1934 and as that term is defined in the Private Securities
Litigation Reform Act of 1995.

curable medicinenet

The companies do not undertake to publicly update or
revise any of their forward-looking statements even if experience or future
changes show that the indicated results or events will not be realized.

prepuce intercourse

] reported a 27 percent loss in
volume of the penis after the radical prostatectomy. Hennenfent, another study [Savoie, et al.org ), founded the
Epididymitis Foundation ( http://www. It's $19. We believe
the data from this extensive Phase IIb program will allow us to confidently
select doses, end points and treatment periods for use in the design of the
pivotal Phase III trials," commented Dr.

Premature Ejaculation, is characterized by ejaculation either before or soon after penetration.

phimosis ciefap

org ).org ., King
Pharmaceuticals (NYSE: KGPTN)
announced today that they have initiated patient enrollment in two double-
blind, placebo -controlled Phase IIb clinical trials of PT-141 in patients with
erectile dysfunction (ED). The main objectives of these studies are to
further evaluate safety, treatment duration, patient populations and a range
of doses that will be incorporated into Phase III pivotal trials. Additionally, the clinical trials will evaluate a range of PT-141
intranasal doses between 5 mg and 15 mg.com. These forward-looking statements reflect
managements' current views of future events and operations, including , but not
limited to, statements pertaining to the potential development and
commercialization of PT-141, and anticipated results and scheduled completion
of the Phase IIb clinical program for PT-141.

Impotence, or more properly Erectile Dysfunction (ED) is the inability to have an erection that is rigid enough or to maintain it long enough to complete sexual intercourse.

curable attendant

com/cgi-bin/prnh/20050503 /CGTU064 )
"I can personally testify that I lost about an inch of penile length,"
says Aubrey Pilgrim, who underwent a radical prostatectomy, "and it takes a
lot of stimulation to have an orgasm and of course it's not the same."
According to Dr."
"The real lesson," says Dr. and CRANBURY , N.

ejaculation penile

Hennenfent, "is not only that the radical
prostatectomy results in smaller penises, but that the radical prostatectomy
has failed to extend overall survival in two randomized controlled trials . BRISTOL, Tenn.palatin.

penetrate retracted

"
"In one study [Fraiman et al.
He previously published "The Prostatitis Syndromes.

premature inability

, "Smaller penises result from
undergoing the radical prostatectomy for prostate cancer ," warns Dr.
"The initiation of these two double-blind, placebo-controlled Phase IIb
clinical trials is a major milestone in the development of PT-141. It is estimated that some degree of ED affects one half
of all men over the age of 40 and that 150 million men worldwide suffer from
ED. is a biopharmaceutical company developing
melanocortin-based therapeutics. For additional information regarding
Palatin, please visit Palatin Technologies' website at http://www.

inability prepuce

Hennenfent. And, in another study
[Walsh et al. Hennenfent. Carl Spana, CEO and President of
Palatin Technologies . The condition is correlated with
increasing age, cardiovascular disease, hypertension, diabetes , hyperlipidemia
and smoking.

premature inability

The Company has one product on the market
generating revenue and a pipeline of product opportunities in development. King, an S+P 500 Index company, seeks to
capitalize on opportunities in the pharmaceutical industry through the
development, including through in-licensing arrangements and acquisitions, of
novel branded prescription pharmaceutical products in attractive markets and
the strategic acquisition of branded products that can benefit from focused
promotion and marketing and product life-cycle management.

Visit the links and become informed about the problem.

erections penile

Bradley
Hennenfent, author of the new book, "Surviving Prostate Cancer Without
Surgery " (Roseville Books, 2005).], no man had as good an erection after surgery as before
surgery, and many men couldn't get an erection at all."
Dr. Hennenfent has seen five uncles suffer from prostate cancer. Other important factors that may cause actual results to differ
materially from the forward -looking statements are discussed in the "Risk
Factors" section and other sections of King's Form 10-K for the year ended
December 31, 2004 and Form 10-Q for the first quarter ended March 31, 2005 ,
and Palatin's Form 10-K for the year ended June 30, 2004 and Form 10-Q for the
third quarter ended March 31, 2005, which are on file with the U.

phimosis erectile

"Although the cavernous nerves are sometimes spared , it
appears that the branches of those nerves, which are always cut during the
radical prostatectomy , are vital for achieving normal, completely rigid,
erections. The
second clinical trial will similarly evaluate 265 diabetic patients with ED.

intercourse ejaculation

(Photo: http://www.newscom. "One abstract [McCullough et al.] directly warns
physicians that: "Men should be counseled before radical prostatectomy that
penile shortening may occur. He co-
founded the Prostatitis Foundation ( http://www. To date,
the Company has formed partnerships with Mallinckrodt, a subsidiary of Tyco
Healthcare, and King Pharmaceuticals.

This topic is dedicated to helping men and their partners become informed on what Erectile Dysfunction is, what causes it, and what can be done about it.

medicinenet impotence

] has documented what some of us have
already concluded from the experiences of men after prostate cancer surgery ,"
says Dr. Men
variously described orgasms after the radical prostatectomy as "only a
shadow ," "possible," "have them but different," "some pain," and "not sure it
happens.

King Pharmaceuticals and Palatin Technologies Initiate Phase IIb Clinical Trials Evaluating PT-141 in Patients Suffering from Erectile Dysfunction

J. In addition, certain prescription drugs and psychogenic issues
may contribute to ED. This new
chemical entity is being evaluated in Phase IIb clinical trials studying the
efficacy and safety profile of varying doses of this novel compound in men
experiencing erectile dysfunction ("ED") and women experiencing female sexual
dysfunction ("FSD"). The mechanism of action of PT-141 may offer important
benefits over currently available products for the treatment of ED because it
acts on the pathway that controls sexual function without acting directly on
the vascular system. The nasal formulation of PT-141 currently under development is
presented in a convenient and non-invasive application. For example,
unlike PDE-5 inhibitors which are contraindicated in patients taking nitrates,
primarily for the treatment of cardiovascular disease, current animal data
indicates that PT-141 may not be contraindicated in patients taking nitrates. Securities
and Exchange Commission.

Phimosis, a condition in uncircumcised men in which the foreskin, or prepuce, cannot be retracted from the head of the penis.

Its causes can be either psychological or physical.

medicinenet peyronie

Prostatitis . Many patients are
contraindicated for, or non-responsive to, PDE-5 inhibitors. Some important factors which
may cause results to differ materially from such forward-looking statements
include dependence on the companies' abilities to carry out their respective
business plans; dependence on the successful development and commercial
acceptance of PT-141; dependence on the companies' abilities to fund
development of PT-141; dependence on whether a commercial product results from
PT-141 development activities; dependence on the companies' abilities to
establish and successfully complete clinical trials necessary for approval of
PT-141 as a treatment for sexual dysfunction; dependence on the actual results
of the Phase IIb clinical program and the actual amount of time it takes to
complete the program; dependence on the companies' abilities to successfully
collaborate in the development and commercialization of PT-141; dependence on
the availability and cost of raw materials; dependence on the unpredictability
of the duration and results of the U.

intercourse medicinenet

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- - kjjkjk

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