Preliminary results indicate that the
currently approved frozen formulation, known as FluMist (Influenza Vaccine
Live, Intranasal), and the investigational, next-generation refrigerator
stable formulation, CAIV-T (cold adapted influenza vaccine, trivalent),
produced similar immune responses .D."
The Phase 3 double-blind study was designed to demonstrate equivalent
immunogenicity (using strain-specific geometric mean titers) of CAIV-T and
FluMist in healthy individuals between the ages of 5 and 49 years. Dedicated to advancing science and medicine to help people live
better lives, the company is focused on the areas of infectious diseases,
cancer and inflammatory diseases .

Call for Pertussis Vaccination for Healthcare Workers Endorsed by National Foundation for Infectious Diseases

org.

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"Completing this Phase 3 study is the key step in our plan to seek U. that is indicated for active
immunization for the prevention of disease caused by influenza A and B viruses
in healthy children and adolescents, 5 to 17 years of age, and healthy adults,
18 to 49 years of age. Securities and Exchange Commission, MedImmune can provide no assurance
that FluMist will be commercially successful . In the U.

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Immunogenicity was evaluated by measuring
antibody levels in blood serum (specifically , serum HAI antibodies) to each of
the three influenza strains contained in the vaccines. For full prescribing
information for FluMist, see the company's website at
http://www.

* For each decade, immunization of healthcare workers could prevent as
many as 100,000 cases of pertussis and save up to $151 million in costs
(direct and indirect).

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, MedImmune, Inc.S. Pertussis is caused by bacteria found
in the mouth, nose and throat.

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"We are pleased that this bridging study has met its primary objective
demonstrating comparable immunogenicity between FluMist and CAIV -T," said
Edward M.
"Healthcare workers need to be protected against pertussis not only for
their own health, but for the health of those in their care," says Susan J.
The U.

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One preparation can be used for both
adolescents and adults, and the other has been approved only for use in
adolescents .
In response to concern about the rising number of pertussis cases, NFID
seeks to increase awareness among the public and healthcare providers about
the disease and the importance of preventive vaccination across age groups.

nose throat

Connor, M. In placebo-controlled clinical trials, the most
common solicited adverse events in the indicated population (n=2,762) included
runny nose/nasal congestion , headache, cough, sore throat, tiredness/weakness,
irritability, decreased activity and muscle aches . For more information, visit
the company's website at http://www.com.S.

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(Nasdaq: MEDI) today announced that the primary objective was met in a Phase 3
study evaluating the immunogenicity of two different formulations of its live,
attenuated intranasal influenza vaccine.

Sites for products or sales of health products should be submitted to Shopping/Health_and_Beauty

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About MedImmune, Inc . "We hope these recommendations will be adopted quickly by
the healthcare community to help reverse the growing number of cases across
all age groups.

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- Primary Endpoint Achieved Demonstrating Equivalent Immune Response -

GAITHERSBURG, Md.
regulatory approval for CAIV-T in healthy individuals 5 to 49 years of age and
replace the frozen formulation of FluMist in the marketplace. Serum samples were
obtained from all participants prior to receipt of the first dose and then
again 28 to 35 days after the last dose of the vaccine., there are approximately eight to 10
million healthcare workers employed in hospital and ambulatory settings; these
workers are at risk of contracting and transmitting pertussis due to
occupational exposure.

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S.S.nfid.

hyperhidrosis incontinence

"

About Pertussis Immunization and Healthcare Workers
Protection from childhood pertussis immunization is now known to wane
starting in adolescence.

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The study
randomized 980 participants at 26 sites in the United States to receive either
CAIV-T or FluMist.

About FluMist
FluMist was approved by the FDA in June 2003.
MedImmune strives to provide better medicines to patients, new medical
options for physicians, rewarding careers to employees, and increased value to
shareholders.

About NFID
Founded in 1973, NFID is a non-profit organization dedicated to public and
professional educational programs about the causes, treatment and prevention
of infectious diseases.

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In addition, no assurance
exists that development efforts for CAIV-T will succeed, that CAIV-T will
receive required regulatory approval or that, even if regulatory approval is
received , CAIV-T will be commercially successful.
Adults with pertussis may experience symptoms such as prolonged coughing,
which is sometimes so severe that it causes vomiting, broken ribs and
pneumonia , and may require hospitalization. For more information about NFID, visit the NFID web
site at http: //www.

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Additional analyses of primary and
secondary endpoints are ongoing and final results are expected to be submitted
to the U.S.

Media Contact:
Jennifer Corrigan, 732-382-8898

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Study results
indicated that CAIV-T and FluMist showed equivalent post-vaccination HAI
antibody titers for all three vaccine strains. In
addition to risks and uncertainties discussed in MedImmune 's filings with the
U. While the severity of
pertussis symptoms varies in adults, it can be a life-threatening illness for
infants who are not fully immunized. Food and Drug Administration approved two vaccines in 2005 that
offer protection against pertussis to adults and adolescents and that also
protect against tetanus and diphtheria.

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Preliminary Results of Phase 3 Bridging Study Show Comparable Immunogenicity of Frozen FluMist(R) and Investigational Liquid Formulation

com. With approximately 2,000 employees
worldwide, MedImmune is headquartered in Maryland.

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Food and Drug Administration later this year for review., executive vice president and chief medical officer. There are risks associated with all vaccines including
FluMist. Such forward-looking statements are based on current
expectations and involve inherent risks and uncertainties, including factors
that could delay, divert or change current expectations and could cause actual
outcomes and results to differ materially from current expectations. MedImmune undertakes no
obligation to update any forward-looking statement, whether as a result of new
information, future events or otherwise except as may be required by
applicable law or regulation. - Recommendations Expected to Help Stem Rising Pertussis Rates -

BETHESDA, Md.
The recommendations call for the tetanus-diphtheria-acellular pertussis
(Tdap ) booster to be routinely given to healthcare workers in place of the
previously recommended tetanus -diphtheria (Td) booster. This development is
in addition to the 2005 ACIP vote to recommend pertussis immunization for both
adolescents and adults.
Rehm, MD, NFID's medical director and an infectious disease specialist at the
Cleveland Clinic.S.

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Additional
studies are ongoing to assess CAIV-T compared to the injectable flu vaccine in
children from 6 months to 5 years of age. Children between the ages of 5 and 8 years of age (n=414)
received two doses of vaccine, while participants 9 years of age and older (n=
566) received one dose of vaccine.

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While final 2005 estimates are not yet available , CDC data
indicate that there were nearly 26,000 cases of pertussis in 2004, the highest
number of case reports in four decades. The illness, referred to by the
Chinese as the "cough of 100 days ," can take months to resolve and causes
adults to have fitful sleep and miss work days. In addition , adults may
spread pertussis to others within close contact.

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It is the first live,
attenuated influenza vaccine in the U.

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medimmune.

This announcement contains, in addition to historical information, certain
"forward-looking statements" regarding the results of clinical trials for
FluMist and CAIV-T.

About Pertussis
Pertussis, or whooping cough, is a highly contagious respiratory infection
characterized by a prolonged, dry cough sometimes associated with a signature
"whoop " sound.

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Like any vaccine, FluMist does not protect 100 percent of
individuals vaccinated.medimmune ., The National Foundation for
Infectious Diseases (NFID) supports new recommendations by the Centers for
Disease Control and Prevention's (CDC) Advisory Committee on Immunization
Practices (ACIP ) that healthcare workers and anyone who works in a healthcare
setting should be protected against pertussis, also known as whooping cough.

Some data from published studies on pertussis and healthcare workers
report:

* The risk of contracting pertussis among healthcare workers is nearly two
times greater than that among the general adult population.

This section provides links to various health products and shopping places.

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