National Foundation for Infectious Diseases Reinforces the Importance of
Influenza Vaccination of Persons 65 and Older

BETHESDA, Md.

The second study [American Journal of Epidemiology, February 14, 2005]
notes that while influenza vaccination of the elderly has been shown to have a
moderate, but important effect on mortality in that age group, as a nation, we
have largely ignored one of the key vectors of influenza -- schoolchildren. Medical Device Market 3 .

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Concerned with protecting and improving the health of communities and populations.

prevention nonprofits

com/cgi-bin/prnh/20040830/AHIPLOGO )

"CMS Administrator Dr.
"Given the recent work by the RAND Corporation showing that approximately
half of current medical practice is not 'best practice,' and the recent post-
marketing discoveries of gaps in knowledge about safety and long-term
performance of interventions, there is a clear need for the establishment of a
process to study the safety and efficacy of new interventions in the short and
long term. Each report
provides a comprehensive analysis of the market and, importantly ,
provides 5-year forecasts by technology category, national data
projections, outlook and key developments such as regulation, health
facilities and government policy.
Around 92% of the medical device market is supplied by imports.

effectiveness populations

Public health includes such diverse topics as preventive medicine; health education and promotion; sanitation and hygiene; communicable-disease control; emergency medical services; assessment and monitoring and organization of health services and policies.

geographically prevention

They note that many previously published
observational studies suggest a higher level of influenza vaccine
effectiveness against death in the elderly than indicated in the NIAID paper.

Research and Markets : Romania Medical Device Market Outlook Report

Romania is located in south-eastern Europe, bordering Hungary,
Ukraine , Moldova, Bulgaria and Serbia with one of the largest
populations in this region.

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"To better ensure patient safety and sound medicine, we support today's
decision by CMS so that all patients receive the most effective and
appropriate treatments. This approach will also support pandemic planning.

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com/reports/c12714) has
announced the addition of Romania Medical Device Market Outlook Report
to their offering
Medistat Outlook Reports are ideal for executives wanting to
understand the key drivers in medical markets worldwide. This will take the Romanian market to US$329 million in 2010.

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The domestic production of medical devices
contributes little towards the market size in Romania , and as a
result, the value of exports is low.

occurrence topically

9 million, or US$11 per capita.

safety effectiveness

Sources
For more information visit
http://www.com/reports/c12714

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NFID Statement Regarding Findings of Two Influenza Vaccination Studies on the Elderly and Schoolchildren

The article concludes
that the best strategy for minimizing the number of influenza-related deaths
and morbidity for interpandemic influenza is to concentrate vaccine in both
high-risk and high-transmitting population groups (schoolchildren )
simultaneously.researchandmarkets.
In 2005, the Romanian market for medical equipment and supplies is
estimated at US$240.

rollins protecting

To date, observational studies on influenza immunization have found the
following:

* When the match between the vaccine and circulating influenza strains is
close, the vaccine is 30%-70% effective in preventing hospitalization
for pneumonia and influenza among elderly persons living outside
chronic care facilities and those persons with chronic medical
conditions. The Health Sector
Reform Project was approved in December 2004 and aims to improve
maternity and newborn care, emergency medical care and rural primary
healthcare .

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"

Contact: Jennifer Corrigan
732-382-8898

Key National Data
Projections 4.

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populations safety

Executive Summary 2.

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This ecological study only looked at overall trends and did not look
at whether the individuals who died were vaccinated or whether they had
underlying conditions . Improvements to the health system continue
to be supported by World Bank-sponsored projects.

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"

America's Health Insurance Plans -- Providing Health Benefits to More Than
200 Million Americans .

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* Among elderly nursing home residents, influenza immunization can be
50%-60% effective in preventing hospitalization or pneumonia and up to
80% effective in preventing death from influenza.
The NFID wants to reinforce the importance of influenza immunization among
persons age 65 and older, who are at high risk for complications,
hospitalizations and death from influenza .

epidemiology publicly

4% per
annum. International Market Comparisons 5.

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The first study, conducted by the National Institute of Allergy and
Infectious Diseases (NIAID) [Archives of Internal Medicine, February 14 ,
2005], looked at overall influenza immunization rates and mortality rates in
the 65+ population and concluded that despite increases in influenza
immunization among this population, there was little change in mortality
rates. Current Centers for Disease and Prevention (CDC)
recommendations are based on observational studies, which compare vaccinated
people with those who choose not to be vaccinated , and are considered by many
experts, including the Centers for Disease Control and Prevention, to be more
appropriate than ecological studies for evaluating vaccine effectiveness.
"The overall body of scientific evidence about the vaccine efficacy and
the public health impact of the disease supports current CDC recommendations,"
said William Schaffner, MD, NFID board member and professor and chairman,
department of preventive medicine, Vanderbilt University School of Medicine. Importantly , the market can be seen
in its global context with international market comparisons.

topically preventive

topically geographically

WASHINGTON , Karen Ignagni, President and CEO of
America's Health Insurance Plans, released the following statement in response
to the Centers for Medicare and Medicaid Services (CMS) Administrator Mark
McClellan 's announcement that Medicare will establish a process for National
Coverage Determinations based on evidence development:
(Logo: http://www.newscom.

, The National Foundation for
Infectious Diseases (NFID) is issuing the following statement in light of two
recent studies which have created some confusion about the importance of
influenza immunization among the elderly (65 +).
The article proposes that future influenza prevention strategies add
schoolchildren as a key target, which will reduce the spread of influenza to
those at high risk for complications of the disease.

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Mark McClellan has established an important
precedent by creating a process that will link coverage determinations to the
development of a stronger evidence base for new interventions in the medical
field.
"In addition, we hope that in the coming months, the immunization community
engages in vigorous discussion about how to implement immunization of
schoolchildren, based on sufficient availability of vaccine. The
USA and Germany are the leading suppliers, accounting for over 60% of
imports in 2002.
1.

interventions rollins

AHIP Statement on CMS Draft Guidance on Coverage Determination With Evidence Development

We see this as an important and necessary step in
expanding the evidence base to complement the rigorous, scientific, clinical
studies performed to ensure patients receive the best treatment from their
providers based on the most recent and accurate medical evidence.
It is important to note that authors of both studies maintain that
immunization of high-risk populations , including the elderly, remains an
important public health strategy.

Business Editors/Health /Medical Writers/Health Editors/Medical
Editors

DUBLIN, Ireland----Research and
Markets (http://www. It is expected
that the device market will continue to expand at a rate of 6.researchandmarkets .

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prevention evidence

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