Palatin Technologies Inc. and King Pharmaceuticals Inc. Report Positive Results of a Phase 2A Pilot Clinical Study Evaluating PT-141 in Female Sexual Dysfunc

and BRISTOL , Tenn. to jointly develop and commercialize PT-141. Up to 40 percent of marriages suffer from a lack of
sexual desire.

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The mechanism of action of PT-141 may offer important
benefits over currently available products for the treatment of ED because it
appears to act on the pathway that controls sexual function without acting
directly on the vascular system. With men wanting more intimacy, and women wanting less, the
sexual chasm is growing, causing friction and feelings of rejection .

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King, an S+P 500 Index company, seeks to
capitalize on opportunities in the pharmaceutical industry through the
development, including through in-licensing arrangements and acquisitions, of
novel branded prescription pharmaceutical products in attractive markets and
the strategic acquisition of branded products that can benefit from focused
promotion and marketing and product life-cycle management. Other important factors
that may cause actual results to differ materially from the forward-looking
statements are discussed in the "Risk Factors" section and other sections of
King 's Form 10-K for the year ended December 31, 2003 and Form 10-Q for the
second quarter ended June 30, 2004, and Palatin's Form 10-K for the year ended
June 30, 2004 and Form 10-Q for the first quarter ended September 30, 2004,
which are on file with the U. The
companies do not undertake to publicly update or revise any of their forward-
looking statements even if experience or future changes show that the
indicated results or events will not be realized.

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"
Eighteen women with a diagnosis of FSD were enrolled in this double-blind,
randomized, placebo controlled, single dose, cross-over clinical study. Patients were administered 2 X 10 mg of intra-nasal PT-141
or placebo spray in a randomized manner and were monitored and evaluated for
three hours post-dose before being discharged from the clinic. (Amex: PTN) is a biopharmaceutical company
focused on discovering and developing melanocortin (MC)-based therapeutics.

Forward-looking Statements
This release contains forward-looking statements within the meaning of
Section 27A of the Securities Act of 1933, Section 21E of the Securities
Exchange Act of 1934 and as that term is defined in the Private Securities
Litigation Reform Act of 1995.
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Palatin Technologies and King Pharmaceuticals plan to more fully present
information regarding the potential market for and clinical benefits of
PT-141, including the treatment of FSD , at a future conference.
Palatin Technologies, Inc. For further information, visit the Palatin web site at
http://www. An edible massage lotion that is condom-friendly can
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D. Current
literature indicates that about 40% of all patients who receive an initial
prescription for a PDE-5 inhibitor do not renew the prescription due chiefly
to adverse side effects, drug interaction issues, and/or the lack of an
acceptable level of responsiveness.palatin. They need to plan to
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Additionally, there was a correlation between sexual desire and genital
arousal in patients receiving PT-141, an observation that further reinforces
the potential importance of these reports.

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J.
(NYSE: KG) announced today positive results of a Phase 2A pilot clinical study
evaluating PT-141 in pre-menopausal women diagnosed with female sexual
dysfunction (FSD). Patients in the study receiving PT-141 reported increases
in their levels of sexual desire and genital arousal compared to placebo. Securities and Exchange Commission. As a result, the new wonder drugs are doing little to increase the
frequency of intercourse in marriages. "For women, sex is mental and
physical. When the amino acid is applied
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About Female Sexual Dysfunction (FSD)
FSD consists of four components, hypoactive sexual desire disorder, female
sexual arousal disorder, dyspareunia or painful intercourse and anorgasmia. Many female partners remain
uninterested in sex.

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The more orgasms a woman has , the more likely it will be that she will
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To establish a diagnosis of FSD , these components must be associated with
personal distress, as determined by the affected woman . A February 10, 1999
study published in the Journal of the American Medical Association, JAMA,
titled , "Sexual Dysfunction in the United States: Prevalence and Predictors,"
states that some form of FSD appears to be prevalent in approximately
43 percent of the female population. This new
chemical entity is being evaluated in Phase 2 clinical trials studying the
efficacy and safety profile of varying doses of this novel compound in men
experiencing erectile dysfunction ("ED") and women experiencing female sexual
dysfunction ("FSD").
Although the current ED market is primarily served by PDE -5 inhibitors
which target the vascular system, a substantial unmet medical need for
alternative sexual dysfunction therapies exists. The Company is
currently conducting clinical trials with its lead drug candidate, PT-141, an
MC receptor agonist, for the treatment of male and female sexual dysfunction. Food and Drug
Administration's ("FDA") review of Investigational New Drug Applications
("IND"), New Drug Applications ("NDA"), and supplemental New Drug
Applications, ("sNDA") and/or the review of other regulatory agencies
worldwide; dependence on compliance with FDA and other government regulations
that relate to King's and Palatin's respective businesses; dependence on
King's and Palatin's abilities to successfully manufacture PT-141; and
dependence on changes in general economic and business conditions; changes in
current pricing levels; changes in federal and state laws and regulations;
changes in competition; unexpected changes in technologies and technological
advances; and manufacturing capacity constraints. Even
over-the-counter medications, like antihistamines, can cause a decrease in
vaginal fluids.

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CRANBURY, N. (Amex: PTN) and King Pharmaceuticals, Inc . Pheromones act as mood elevators to create a sexy state of mind.

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Additional conditions that can cause vaginal dryness include
pregnancy, childbirth, menopause and changes during the menstrual cycle.

Pheromone-enhanced lotions and shower gels
can help block out the challenges of the day, allowing women to focus on
romance. Additionally, women can use playful products to heighten passion
with their mates. Passion games, such as body finger paints, can also help a
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Adverse events reported include nausea,
headache and nasal congestion. A simple
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,
Palatin Technologies, Inc. We
anticipate that the nasal formulation of PT-141 currently under development
will be as convenient as oral treatments and more patient-friendly than
invasive treatments for ED, such as injections and trans-urethral pellets. It
also appears to result in a rapid onset of action. Some important factors which may cause results to
differ materially from such forward-looking statements include dependence on
the companies' abilities to carry out their respective business plans;
dependence on the successful development and commercial acceptance of PT-141;
dependence on the companies' abilities to fund development of PT-141;
dependence on whether a commercial product results from PT-141 development
activities; dependence on the companies' abilities to establish and
successfully complete clinical trials necessary for approval of PT-141 as a
treatment for sexual dysfunction; dependence on the companies' abilities to
successfully collaborate in the development and commercialization of PT-141;
dependence on the availability and cost of raw materials; dependence on the
unpredictability of the duration and results of the U.S.

While pharmaceutical companies continue to forge ahead
with new drugs to improve men's sexual health, they largely overlook women's
concerns. New scientific advances like L-arginine can accelerate and
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Palatin's patented drug discovery platform, MIDAS(TM), streamlines the drug
design process with an efficient approach to identifying lead compounds from
proteins.
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, President and Chief Executive Officer of Palatin
Technologies. Based on early clinical data, we believe
that PT-141 should not be contraindicated in patients taking nitrates. "Women are complex creatures,"
says Passion Parties President Patricia Davis.
Without enough lubrication, sex can feel raw and sometimes painful.
They are natural attractants that signal your partner that you are ready for
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The company's exclusive RomantaTherapy(R) collection contains sensual body
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Later, during one-on-one consultations, the women privately ask
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NeutroSpec(TM), the Company's proprietary radiolabeled monoclonal antibody
product for imaging and diagnosing infections, has been approved by the FDA as
an imaging agent for the diagnosis of equivocal appendicitis.

About King Pharmaceuticals
King , headquartered in Bristol, Tennessee, is a vertically integrated
branded pharmaceutical company.

Pharmaceutical Companies Design Dapoxetine to Eliminate Premature Ejaculation
in Men , Yet Neglect Sexual Solutions for Women

LAS VEGAS, This week, at an annual meeting of the
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Michael
Perelman, Co-director, Human Sexuality Program, New York Hospital, Cornell
University Medical Center and were confirmed by Dr. Perelman to have a
diagnosis of FSD.

About PT -141
PT-141 is the first compound in a new drug class called melanocortin
receptor agonists under development to treat sexual dysfunction.

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Women need to set sex as an important priority ." The company leads the party-plan industry as North America's premier
and largest supplier of sensual products.

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"As we collaborate with King Pharmaceuticals to further develop
PT-141, we are confident in our collective abilities to efficiently design and
complete future clinical trials that more thoroughly explore the potential
benefits of PT-141 as a treatment for FSD. For example, PDE-5
inhibitors are contraindicated in patients taking nitrates, primarily for the
treatment of cardiovascular disease .
In August 2004, Palatin entered into a strategic collaboration agreement with
King Pharmaceuticals , Inc." Davis suggests the following for women who are having
difficulty igniting that sexual spark with their loved ones." To schedule a party or learn more about
the company, visit: http://www .

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All
patients enrolled in this clinical study were evaluated by Dr. All patients
completed a Treatment Satisfaction Index at 24-hours post-dose as a means of
measuring their levels of sexual desire, genital arousal and, if applicable,
satisfaction with sexual intercourse.

About Palatin Technologies, Inc. NeutroSpec is
marketed and distributed by Palatin's strategic collaboration partner,
Mallinckrodt Imaging, a business unit of Tyco Healthcare.S. We have to invest in preparing our minds and bodies for intimacy
with our partners.

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Due to the demands of work, family, and household chores, women are often
mentally and physically unprepared for sex.

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"We designed this pilot study to take a preliminary look at the effects of
PT-141 as a treatment for FSD; that the results showed improvements in both
genital arousal and sexual desire in such a small study population are
encouraging and warrant the continued investigation of PT-141 in women with
FSD," said Carl Spana, Ph.com. Many women are unaware
that their lubrication levels can easily fluctuate or diminish .

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Clinical data indicates that PT-141 may be
effective in treating a broad range of patients suffering from ED. These forward-looking statements reflect
managements' current views of future events and operations, including, but not
limited to, statements pertaining to the potential development and
commercialization of PT-141.

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