"We believe this
second license agreement
supports the use of our Potelligent Technology as a method for enhancement
of
ADCC and its ability to deliver more highly potent antibodies for more
effective clinical response
. BioWa creates and develops enhanced
ADCC antibodies for itself and others, offering a full range
of antibody
discovery and development capabilities. Sinovac's split flu
vaccine received approval
of its New Drug Certificate in March 2005.sinovac.
footprints apres
J.biowa.com.weil spelunking
Medarex plans to use the
Potelligent
Technology to enhance the ADCC function of selected Medarex
antibodies for potential therapeutic
applications, including cancer.;
Medarex(R), the Medarex logo and UltiMAb(R) and are trademarks of
Medarex,
Inc. The feedback from the attendees
was very positive.
Sinovac is currently the
world leader in the development of a SARS
vaccine.
GulfWest also announced that it has successfully
re-entered and is
now drilling its second horizontal well in the Glen Rose formation in
the Iola
Field of East Texas.cave communicating
ADCC activity is one mechanism of some already
launched anticancer therapeutic
antibodies on the market today., Ltd.
It can be recommended to protect people against Hepatitis
A
and Hepatitis B.
Bilive(TM) is a combined vaccine formulated by purified
inactivated
Hepatitis A virus antigen and recombinant (yeast)
hepatitis B surface (HBsAg), absorbed into aluminum
hydroxide. It is preventable with safe effective vaccines.GulfWest Update on Financing and Drilling
Activity
Speleology is the exploration, study, conservation and enjoyment of caves and other underground
structures.
speleo leptospirosis
About Medarex, Inc. Each year in the United
States, an estimated 200,000 persons
are newly infected with hepatitis
B virus.outdoors fascinating
com.
Medarex is a biopharmaceutical company focused
on the discovery,
development and potential commercialization of fully human antibody-based
therapeutics
to treat life-threatening and debilitating diseases, including
cancer, inflammation, autoimmune disorders
and infectious diseases.com. Medarex disclaims, however, any intent or obligation to update
these
forward-looking statements. Risks and uncertainties include risks
associated with product discovery
and development, uncertainties related to
the outcome of clinical trials, uncertainties related to
product manufacturing
as well as risks detailed from time to time in Medarex's public disclosure
filings with the U.cavers nothing
Enhancement of
this activity is in the spotlight as one promising possibility
for the next
generation of antibody technology. These chronically infected people are at high risk
of
death from cirrhosis of the liver and liver cancer, diseases that kill
about one million people
each year.
Sinovac now has two vaccines fully approved for sale in China -
Healive(TM) for
Hepatitis A and Bilive(TM) for Hepatitis A+B combined.potentially communicating
Bilive(TM) junior is for use in non-immune children
and
adolescents from ages 1 to 15 years, and Bilive(TM) dult is for use in
non-immune adults and
adolescents 16 years of age and older.
Sinovac Biotech Ltd.speleology nothing
, BioWa, Inc.
"We are very
pleased to announce the expansion of our relationship with
Medarex, and to have Potelligent Technology
combined with Medarex's human
antibody technology and pipeline of therapeutic products," said Dr
. Nobuo
Hanai, President and CEO of BioWa. We believe that working with Medarex, a leading
human
therapeutic antibody company, is key to advancing the goals of BioWa to
bring about safe and more
effective treatments for cancer and other life-
threatening and debilitating diseases. For more
information about BioWa
visit its web site at http://www. Copies of Medarex's public disclosure filings
are available from its
investor relations department.
About Hepatitis B
Hepatitis B
is a very common infection. The successful re-entry and
re-completion of wells in Texas, Louisiana
and Colorado is part of
GulfWest's business plan to apply various enhancement technologies to
re
-develop previously abandoned and deeper, domestic natural gas and
oil reserves.cavers leptospirosis
BioWa Grants the Second
Potelligent(TM) Antibody Technology License to Medarex
PRINCETON, N."
"We are very
excited about the promise of utilizing the Potelligent
Technology for the generation of potentially
more efficacious antibodies,"
said Donald L.
Potelligent(TM) Technology involves the reduction
of the amount of fucose
in the carbohydrate structure of an antibody. BioWa is the exclusive
worldwide
licensor of Potelligent(TM) Technology. ADCC is a critical function of the immune system that enhances
the
ability of antibodies to kill tumor cells. The
vaccine induces the body's immune system to
generate antibodies as a
reaction against hepatitis A and hepatitis B viruses. Overall, an estimated
1. Nearly 300 million persons in the world are
chronically infected with hepatitis B virus.
For
further information please refer to the Company's filings with
the SEC or refer to Sinovac's website
at www.com
THIS NEWS RELEASE MAY INCLUDE FORWARD-LOOKING STATEMENTS WITHIN
THE MEANING OF
SECTION 27A OF THE UNITED STATES SECURITIES ACT OF
1933, AS AMENDED, AND SECTION 21E OF THE UNITED
STATES SECURITIES AND
EXCHANGE ACT OF 1934, AS AMENDED, WITH RESPECT TO ACHIEVING CORPORATE
OBJECTIVES
, DEVELOPING ADDITIONAL PROJECT INTERESTS, SINOVAC'S
ANALYSIS OF OPPORTUNITIES IN THE ACQUISITION
AND DEVELOPMENT OF
VARIOUS PROJECT INTERESTS AND CERTAIN OTHER MATTERS.
Speleology is a potentially
dangerous extreme sport.
leptospirosis caves
Drakeman, President and CEO of Medarex.
27, 2005, did not change.
'Take
nothing but pictures, leave nothing but footprints, kill nothing but time.
leptospirosis apres
cancer cells. Top medical
professionals and hepatitis specialists
from across China, and about 130 doctors from China's Center
of
Disease Control attended the launch. The original maturity date of the loan, Oct.speleological caving
Twenty-three
of these therapeutic product candidates derived from
Medarex technology are currently in human clinical
testing, with two of the
most advanced product candidates presently in Phase III clinical trials
.medarex. Statements that are not historical
facts, including statements preceded by, followed by
, or that include the
words "potential"; "believe"; "anticipate"; "intend"; "plan"; "expect";
"estimate"; "could"; "may"; or similar statements are forward-looking
statements.
(OTCBB:GULF)
announced today that it has obtained a one-month
extension on certain changes in the terms and conditions
of a loan
from the company's major lender that were to go in effect at the end
of January, 2005
.leptospirosis nothing
BioWa and Medarex Announce Expansion of Licensing Agreement for BioWa's Potelligent(TM) Technology
Hepatitis is one
of the major diseases of mankind and continues to be a serious global
public
health issue.
Final approval of the Company's flu vaccine is expected in 2005 after
GMP certification
of the new flu vaccine production line. It is highly recommended that you contact a local organisation
to commence your participation in this fascinating recreation.
cave nothing
About BioWa
BioWa is
a wholly owned subsidiary of Kyowa Hakko Kogyo Co, Ltd.Sinovac Biotech Ltd. Announces That it has Launched
the Marketing of its Proprietary Combined Hepatitis A+B Vaccine Bilive'TM'
Preliminary Phase I
results show that this SARS vaccine is
safe and induces SARS-neutralizing antibodies in the human
body.outdoors karst
(Nasdaq: MEDX) today announced that BioWa has granted a second license to
Medarex to use
BioWa's Potelligent(TM) Technology for the enhancement of
antibody-dependent cellular cytotoxicity
(ADCC). Research shows that
Potelligent(TM) Technology significantly enhances binding affinity of
antibodies for Fc receptors and increases ADCC activity in vitro. Medarex
applies its UltiMAb
(R) technology and product development and clinical
manufacturing experience to generate, support
and potentially commercialize a
broad range of fully human antibody product candidates for itself
and its
partners.
Of the 2 billion people who have been infected with the hepatitis
B virus
(HBV), more than 350 million have chronic (lifelong)
infections. Sinovac is one of the leading emerging
biotechnology
companies in China. For further
discussion regarding the information in the press
release and other
risk factors, please refer to the Company's 10-K for Dec. 31, 2003,
and 10Q
for the period ended September 30, 2004.nss leptospirosis
g., Japan's
leading pharmaceutical and largest biotech company
. Sinovac held its official marketing launch for the sale of
Bilive(TM) during the period of March
25-27 in Huang Mountain, Anhui
Province, China.
Sinovac expects to record the first sales of Bilive
(TM) by May 2005.
The Hepatitis A vaccine, Healive(TM), is currently experiencing strong
sales
growth in China.
The matters discussed herein may contain "forward-looking"
statements that
involve risks and uncertainties including, without
limitation, competitive factors in the marketplace
.cave weil
BioWa is currently developing ADCC enhanced monoclonal
antibody-based therapeutics to fight cancer
and other life-threatening and
debilitating diseases and both BioWa and Kyowa have Potelligent(TM
) antibody
products in various clinical stages.
Medarex is committed to building value by developing
a diverse pipeline of
antibody products to address the world's unmet healthcare needs. All rights
are reserved. High rates of chronic
infection are found in some parts of China, Southeast Asia, Africa
,
the Pacific islands, the Amazon Basin in South America, and the Middle
East.
About Sinovac
Biotech Ltd. specializes in the research, development,
commercialization, and sales of human vaccines
for infectious
illnesses such as hepatitis A and hepatitis B, influenza, "SARS", and
avian flu
. CDC controls the Chinese vaccine market through its two
main functions: as both the commercial sales
agency and the
governmental department in the pharmaceutical sector for China.speleo spelunking
About Potelligent
Technology
Antibody-dependent cellular cytotoxicity (ADCC) activity is an important
function
of the human immune system, whereby immune cells can kill target
cells, e.
Business
Editors/Energy Editors
HOUSTON----GulfWest Energy Inc.
Speleology, caving, potholing, spelunking
and urban speleology are all common terms that refer to these activities.
'
uis speleological
News Editors
BEIJING----Sinovac Biotech Ltd. Bilive(TM) will be sold in two forms based on the age
of vaccinees
. Sinovac's Hepatitis A+B combined vaccine,
Bilive(TM), received approval in China in January 2005
and is expected
to achieve similar sales growth to Healive(TM).clickable speleo
Detailed licensing terms/financial
terms were
not disclosed. For more
information about Medarex, visit its website at http://www
.
China is a country that has been greatly affected by viral
hepatitis for a long time.25 million
people
in the United States have chronic hepatitis B virus infection, and
4,000 to 5,000 people
die each year from liver disease or liver cancer
related to hepatitis B.com
If you would like
to receive regular updates on Sinovac please
send your email request to info@sinovac.
leptospirosis communicating
Potelligent(TM) Technology
creates high antibody-dependent cellular cytotoxicity (ADCC) monoclonal
antibodies.S.
Potelligent(TM) is the trademark of Kyowa Hakko Kogyo Co. In
addition, the
Company is co-developing a human vaccine targeting the
avian flu virus in partnership with the China
Center of Disease
Control (CDC). THESE STATEMENTS
ARE MADE UNDER THE "SAFE HARBOR" PROVISIONS
OF THE UNITED STATES
PRIVATE SECURITIES LITIGATION REFORM ACT OF 1995 AND INVOLVE RISKS AND
UNCERTAINTIES
WHICH COULD CAUSE ACTUAL RESULTS TO DIFFER MATERIALLY
FROM THOSE IN THE FORWARD-LOOKING STATEMENTS
CONTAINED HEREIN. Additional
information can also be found on the GulfWest Web page at
gulfwestenergy
.spirochetal speleological
The
agreement provides Medarex with nonexclusive commercial rights to develop
antibodies for
an undisclosed number of targets. There can be no assurance that
such development efforts will succeed
or that other developed products will
receive required regulatory clearance or that, even if such
regulatory
clearance were received, such products would ultimately achieve commercial
success
. During the meeting, it was further agreed that the
Chinese vaccine industry will promote the use
of inactivated vaccines
such as Sinovac's Bilive(TM) in the prevention of infectious diseases
such
as viral hepatitis.
About Bilive(TM)
Bilive(TM) is a state-of-the-art combined hepatitis
A and B
vaccine.cave footprints
and Medarex, Inc. In return, BioWa will
receive license fees, and could receive
milestone payments and royalties on
products developed by Medarex. The enhancement of ADCC is seen
up
to 100 fold in vitro.
For Medarex: Except for the historical information presented
herein,
matters discussed herein may constitute forward-looking statements that are
subject to
certain risks and uncertainties that could cause actual results to
differ materially from any future
results, performance or achievements
expressed or implied by such statements. Securities and Exchange
Commission (SEC), including its
Annual Report on Form 10-K for the fiscal year ended December 31
, 2004 and
subsequent Quarterly Reports on Form 10-Q.
("Sinovac") ("the Company") (AMEX:SVA) announces
that it has commenced
the marketing launch of Bilive(TM), its combined Hepatitis A + B
vaccine
. More than 11,000 of these people are hospitalized, and 20,000
remain chronically infected. The loan
was part of a refinancing that closed at
the end of April, 2004.karst clickable
One
potential benefit of Potelligent
(TM) derived therapeutic antibodies is greater
tumor cell killing activity than with conventional
antibodies. The prevention and control of hepatitis is
very important for the country's social development
and public health.leptospirosis speleolabs
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