The panel will also introduce some of the most promising
applications for optical technology.

SHEDDING LIGHT ON BRAIN TUMORS AND CLOGGED ARTERIES

Using a practical laser-based fiber-optics system, researchers
have developed a minimally invasive technique that can tell the
difference between dangerous and less harmful forms of atherosclerotic
plaque in 34 human patients.
Developed by a team of engineers and surgeons at Cedars-Sinai Medical
Center in Los Angeles and the University of Southern California, the
system makes use of a technique called "time -resolved laser-induced
fluorescence spectroscopy" (TR-LIFS). There, the probe shines the laser light on
tissue, and researchers or physicians record the spectrum of light
that the tissue radiates (or "fluoresces") in response.
This sensitive optical system removes the need for many biopsies and
makes it easier to distinguish between similar types of tissue. Now, a Cornell-Rochester-Duke team presents a new method of
slowing down light, one that is especially practical, as it can be
operated over a wide range of wavelengths, including those useful for
telecommunications.
The researchers use this effect to construct an optical delay, in
which a pulse of light is postponed for up to 1 . For more information, visit the conference's Web site at
www.

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C."
The site offers easy navigation to information and breaking news from
every facet of Michelin North America, including every product line from
bicycle and passenger car tires to giant earthmover tires and travel guides., Michelin North America employs more than
23,000 and operates 20 plants in 16 locations.aspx
or contact OSA's Colleen Morrison at 202-416-1437, cmorri@osa.org

PRESS LUNCHEON

A private press luncheon panel will take place on Tuesday, May 24,
at noon in room 333., Arpad Bergh of the Optoelectronics Industry Development
Association will discuss the convergence of traditional industry
segments -- communications, computers and consumer electronics -- and
how it may lead to new optoelectronics markets.org

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Virtual Newsroom Offers 24-7 Access to Latest News from Michelin North America

GREENVILLE, S. - 4:00 p. - 6:00 p. This information, for
example, can tell physicians whether artery plaque is dangerously
inflamed, consisting of foam cells rich in lipids, or if they are less
dangerous due to a collagen-rich composition. Speaking at the CLEO meeting, UCSD's Victor Lien will
describe how marrying microfluidics (fluids moving through tiny
channels) to photonics produces a thousandfold reduction in size,
weight and cost for performing one of two core functions of flow
cytometry: cell detection with very high sensitivity. The Harvard confocal
light scattering spectroscopic (CLSS) microscope achieves pictures of
100-nm organelles with 5-nm accuracy, allowing it to look for clumping
of the genetic material known as chromatin, an early sign of cancer,
inside the cell nucleus.

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The virtual newsroom gives us the ability to post news -- from racing results
to international developments that impact North America -- literally at any
time, day or night. The company also publishes travel guides,
maps and atlases covering Europe, Asia, Africa and North America .

For more information, visit http://www. In addition, the same technique
distinguished brain tumors from normal tissue in 18 patients. Rapidly
heating metals and watching how their atoms rearrange themselves can
provide insights into the extreme conditions inside stars and the
interiors of planets as well as the extreme states of matter that
approach nuclear fusion temperatures. Cell counters operate according to a principle
known as flow cytometry, the study of cells as they move past
detectors in a fluid stream. Combining metamaterials with
conventional materials might lead to new kinds of cell-phone antennas
which could provide better reception and coverage. Now, a
collaboration between the University of Karlsruhe in Germany and Iowa
State University is reporting a metamaterial designed for
electromagnetic radiation at a record high frequency of around 100
terahertz (equivalently , a 3-micron wavelength), in the infrared
portion of the electromagnetic spectrum.

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A meeting Press Room will be located in the Baltimore Convention
Center in the Pratt Street East Office.m.m.
(Presentation CFJ3, "Applications of Time-Resolved Fluorescence
Spectroscopy to Atherosclerotic Cardiovascular Disease and Brain
Tumors Diagnosis")

WATCHING METALS MELT: INSIGHTS FOR PLANETS, STARS AND EXTREME
STATES OF MATTER

In what may provide deep insights into what goes on inside planets
and stars, scientists have captured the first atomic-level view of the
melting process, one of the simplest transformations of matter, on the
timescale of femtoseconds, or quadrillionths of a second.

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Those interested in
obtaining a meeting badge for the Press Room should register online at
http://www. In the realm of brain
surgery, it allows surgeons to determine the boundaries of aggressive
brain tumors (glioblastoma) in real-time during surgical procedures. The hope is to make these often -important
cell counters more available to primary care physicians, potentially
enabling patients to get cell counts in the office without having to
travel to a lab. According to the researchers , this technique
has potential applications in such areas as obstetrics/gynecology and
drug design . (Paper CThC1, "Application of Confocal Light Scattering
Spectroscopic Microscopy to Monitor Subcellular Organelles")

SLOW LIGHT MEANS BETTER TELECOMMUNICATIONS

In the past few years, researchers have slowed down light from its
normal speed of 186,000 miles per second to zero velocity. CLEO/QELS combines the
strength of peer-reviewed scientific programming with an
applications-focused exhibition to showcase the present and future of
this technology.

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The press luncheon will convene representatives
from the scientific, corporate and analyst communities to discuss the
business and science sides of optics, highlight the most intriguing
new research in the field, and offer an overarching perspective on
significant new developments to be unveiled during CLEO/QELS and
PhAST. Instead of
mainframe lasers and photodetectors, the UCSD device, which they call
a fluidic photonic integrated circuit (FPIC), uses tiny light-emitting
diodes and silicon detectors for triggering, and then monitoring
fluorescence from, passing cells to detect them with 10,000 times
better sensitivity than before .

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, Journalists can often tell time
by their deadlines because they loom at all hours of the day.

To make it
easier for reporters to research and compile stories, Michelin North America
has created a virtual newsroom at http://www.michelinmedia.

Nanometer-Scale Views inside Cells New Light on Brain Tumors and a Novel Method for Slowing Down Light Showcased at 2005 CLEO/QELS

cleoconference. Using this process, surgeons
take a fiber-optic probe connected to a laser to access the desired
location in the body. With
their initial clinical successes, the researchers hope to help
fluorescence spectroscopy become a widespread clinical technique. Electron microscopy produces sharp pictures but
preparing the specimen to enable viewing necessarily kills the cell. A new method, reported by Lev Perelman of Harvard, avoids
the foregoing problems by combining the use of tight pinholes to
control incoming and collected light (Confocal Microscopy) and
analyzing the spectrum of scattered light coming from the sample
(Light Scattering Spectroscopy). Such a feat
may be useful, for example , in using light to make more powerful
all-optical versions of computers, memory chips and telecommunications
systems.

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"Our commitment is to make
information from Michelin easy to access and always available to the media.

The world's largest tire maker, Michelin (http://www.m.org/media_center/MediaRegistrationForm .

HIGHLIGHTS

Following are a few of the many highlights to be discussed at the
conference . The experiments are revising scientists' basic knowledge of
what happens during rapid melting. Starting out
decades ago as a room-sized operation, counting cells is now a
tabletop operation but scientists at the University of California at
San Diego (UCSD) aim to reduce the size much further, to the point
where it could eventually become part of a highly portable, miniature,
circuit-based system. In addition, a flat
panel of metamaterial might enable the construction of a "perfect
lens" which can image objects -- at least according to theory -- with
limitless detail (resolution). (Presentation
JThC1, "Towards Left-Handed Metamaterials at Optical Frequencies")

About CLEO/QELS

With a distinguished history as one of the industry's leading
events on laser science, the Conference on Lasers and Electro-Optics
and the Quantum Electronics and Laser Science Conference (CLEO/QELS )
is where laser technology was first introduced.

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The meeting is
co-sponsored by the Optical Society of America (OSA), the American
Physical Society (APS) and the IEEE Lasers + Electro-Optics Society
(IEEE/LEOS). The Press Room will be open
Sunday, May 22, from 12:00 p.m. At the Wednesday, May 25, 8
a.
Determining the presence and abundance of white-blood cells, for
example, is integral for diagnosing cancer and AIDS. (Presentation CFF2,
"Fluidic Photonic Integrated Circuit (FPIC) for Cytometric Detection")

STUDYING TINY CHANGES IN LIVING CELLS

There have been several ways to study the structure and behavior
of organelles, distinct cell structures such as the nucleus and
mitochondria. For instance, this would allow for
rewritable optical discs with unmatched storage density. The material does not yet
exhibit a negative index of refraction, and there is no "perfect
lensing" of the 3-micron wavelength radiation, but the Karlsruhe-Iowa
group is working on this , as well as on metamaterials at even higher
frequencies suitable for telecommunications wavelengths . Sponsored by the American Physical Society's (APS)
Laser Science Division, the Institute of Electronic Engineers/Laser
and Electro-Optics Society (IEEE/LEOS) and the Optical Society of
America (OSA ), CLEO/QELS provides an educational forum, complete with
a dynamic Plenary, short courses, tutorials , workshops and more, on
topics as diverse as its attendee base whose broad spectrum of
interests range from biomedicine to defense to optical communications
and beyond.cleoconference.

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org

PLENARY SESSION

At two plenary and awards sessions, distinguished speakers will
present talks on cutting -edge optics topics. Shuji Nakamura of the
University of California at Santa Barbara will discuss future
prospects for solid-state lighting, which promises a much more
energy-efficient form of illumination. The researchers have extended their experiments
to study the melting of metals, such as gold, which may increase
understanding of warm dense states of matter as a prelude to nuclear
fusion. (Presentation CMCC3, "Tunable
All-Optical Delays via Brillouin Slow Light in an Optical Fiber")

PROGRESS TOWARDS COMPOSITE MATERIALS WITH A NEGATIVE INDEX OF
REFRACTION FOR VISIBLE LIGHT

A few years ago physicists devised a "metamaterial" -- an
artificial composite material made of tiny rods and small split rings
-- which had a very curious optical property.

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Viewing separate cells at different phases of development can provide
a proper time sequence, but this involves much tedious labor. One builds up a complete image by
scanning the microscope across the specimen.

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michelin.

Business Editors
CLEO/QELS 2005

WASHINGTON----Researchers will
present new results in the realm of optical science between May 22-27,
2005, in Baltimore, Maryland , at the 2005 Conference on Lasers and
Electro-Optics (CLEO), which is being held jointly with the Quantum
Electronics and Laser Science Conference (QELS) and the Photonic
Applications System Technologies (PhAST) Conference. To register for the press
luncheon contact OSA's Colleen Morrison at 202-416 -1437,
cmorri@osa. Additionally, Chris Contag of Stanford will
show how optical imaging can reveal the factors that cause stem cells
either to self-renew (replicate themselves) or differentiate (develop
into more specialized cells). As team member
Laura Marcu will report, the fluorescence emission from the tissue can
provide information on its chemical composition. Demonstrated by a University of
Toronto team led by Professor Dwayne Miller, an intense, ultrafast
pulse of laser light melts the target material, followed by a beam of
electrons that bounces (or "diffracts") through the material to
provide information on the positions of the atoms at any given
instant.

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com)
manufactures and sells tires for every type of vehicle, including airplanes,
automobiles, bicycles, earthmovers , farm equipment, heavy-duty trucks,
motorcycles and the space shuttle. On Monday, May 23, at
6:30 p. session, Deborah Jin of JILA/University of Colorado will talk
about fermionic condensates, ultracold gases of matter that are
enabling researchers to explore some fundamental physics phenomena
such as superconductivity. The
system utilizes off-the-shelf components, which reduce its overall
cost and allow for straightforward integration with existing
telecommunications infrastructure. Namely , it had a
negative index of refraction: Microwave radiation impinging onto the
metamaterial's surface bent (refracted) in the opposite direction as
it did for ordinary materials.

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"Today , information is instantaneous," said Lynn Mann, director of public
relations for Michelin North America , Inc.m. The method employs a phenomenon known as Brillouin
scattering, in which the energy of the optical wave is exchanged with
acoustical waves, then re-converted to a lightwave of lower frequency .3 times the pulse
duration. The technique might be useful for future all-optical systems
that store random access memory and perform data synchronization.

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michelinmedia.
The site was developed and is maintained by Wieck Media.C. The trouble
is that the fabrication of metamaterials with a negative index of
refraction becomes more difficult as one aims for higher, more
practical frequencies , such as those in the visible spectrum.

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Journalists can review information on every aspect of the company and,
after completing a simple registration process, can download the full content,
including high resolution photography and digital video at no charge.com .m. Raising the temperature of solid
aluminum to approximately 1000 degrees in less than 1 picosecond (a
heating rate of more than a million billion degrees per second), the
researchers found that the aluminum atoms, initially arranged like
oranges in a grocery display, are vigorously shaken off by the laser
beam, with the atoms at the corners shaken off first, followed by
those closer inside. A second
method, using fluorescent probes coupled with light microscopes,
sometimes saves the cell but can interfere with its normal
functioning.

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com that offers the
latest news, photography and broadcast quality video around the clock.
Headquartered in Greenville, S. and Monday, May 23 -
Thursday , May 26, from 7:30 a. (Presentation CTuAA1, "Femtosecond Electron Diffraction: An
Atomic-Level View of Condensed Phase Dynamics")

TINY CELL COUNTER MIGHT MAKE CRUCIAL MEDICAL TESTS MORE AVAILABLE

Detecting and counting cells is crucial for clinical diagnosis. The researchers are using their device
for detecting stem cells and cancer cells.