, Ingenuity announced today
that it has entered into a multi
-year agreement with the Bristol-Myers Squibb
Company (NYSE: BMY) for the licensing and deployment
of both the Ingenuity
Pathways Analysis application and the Ingenuity Pathways Knowledge Base.pests pathology
(
"Senesco" or the "Company") (AMEX:SNT) and Rahan
Meristem, Ltd. Senesco has undertaken preclinical
research
in certain areas of human health.mycology plant
phytoplasmas pathology
pathology plant
"
About Rahan Meristem
Rahan Meristem is
considered one of the most outstanding companies
for the selection, breeding and production of vegetatively
propagated
plants.
About Senesco Technologies, Inc. Actual results could differ
materially
from such statements expressed or implied herein as a
result of a variety of factors, including,
but not limited to: the
development of the Company's gene technology; the approval of the
Company
's patent applications; the successful implementation of the
Company's research and development programs
and joint ventures; the
success of the Company's license agreements; the successful conversion
of
the Company's letter of intent into a license agreement; the
acceptance by the market of the Company
's products; competition and
the timing of projects and trends in future operating performance, as
well as other factors expressed from time to time in the Company's
periodic filings with the Securities
and Exchange Commission (the
"SEC").
About Ingenuity Systems
Ingenuity Systems
is helping life science researchers understand
biological systems that are foundational to human
health and disease.botany herbaceous
ingenuity.respond regulated
Senesco takes its name from the scientific term for the aging of
plant cells: senescence.
The Company believes that its technology can be used to develop
superior
strains of crops without any modification other than delaying
natural plant senescence. Delaying
apoptosis may have applications to certain
diseases such as glaucoma, ischemia and arthritis, among
others.phytopathology verticillium
("Rahan") announced today that field trials of
Senesco/Rahan banana plants have shown increased
tolerance to the
Black Sigatoka disease, as measured on an index of tolerance widely
used in the
industry for this disease. The Company has developed technology that
regulates cell life.wilts nematodes
pests herbaceous
"By
deploying Ingenuity Pathways Analysis (IPA) to all Bristol-Myers Squibb
scientists, and by integrating
IPA and the Ingenuity Pathways Knowledge Base
with existing Bristol-Myers Squibb bioinformatics solutions
, Bristol-Myers
Squibb will create an integrated pathways workflow for Bristol-Myers Squibb
researchers
that has the opportunity to impact decisions at every stage from
early discovery to late-stage development
.verticillium respond
Delaying cell breakdown in plants extends
freshness after harvesting, while increasing crop yields
and
resistance to environmental stress for flowers, fruits and vegetables.
Senesco partners with
leading-edge companies and earns research and
development fees for applying its technology to enhance
its partners'
products. Using IPA, scientists are
finding value in using a pathways and functional
analysis approach to
understand the biology of their experimental data across all areas of the drug
discovery and development applications spectrum, from target identification
and validation to
biomarkers, predictive toxicology, and patient
stratification.com/trial.pests weeds
bacteria pesticides
herbaceous verticillium
Black Sigatoka, which
is also referred to as Black Leaf Streak
Disease ("BLSD"), is the predominant leaf spot disease of
banana and
is known to cause significant reductions in leaf area, yield losses of
50% or more
, and premature ripening, a serious defect in exported
fruit.pathology plant
"
"Black Sigatoka is a primary focus
of research in the banana
industry," stated Bruce Galton, President and CEO of Senesco. Senesco is
headquartered in New Brunswick, New Jersey, and
utilizes research laboratories at universities and
research centers
throughout North America.Ingenuity Pathways Analysis and Ingenuity Pathways Knowledge
Base Licensed by Bristol-Myers Squibb
Fully functional complimentary trials are available
to qualified
scientists at http://www.com.fungal botany
We are now working with our partners at Rahan to
combine
disease tolerance and extended shelf life into one product,
which we hope will move towards our goal
of commercialization. Rahan's tissue culture lab is among the
most advanced in the world and is the
nucleus of a highly integrated
R+D network of acclimatization houses, nurseries and experimental
plots.
Accelerating apoptosis may have applications to development of
cancer treatments.ingenuity
.mycology pathogen
Ingenuity delivers systems biology expertise to biologists and
bioinformaticians through pathways
analysis software, genome-scale computable
network databases, and knowledge management services and
infrastructure,
resulting in increased productivity and faster drugs to market.
pests plant
Senesco
and Rahan Meristem Report Positive Disease Resistance Results from Banana Field Trials
These
field trial data corroborate the Company's earlier findings
that its proprietary Factor 5A technology
confers resistance to fungal
pathogens by preventing premature plant cell death. As a result, this
press release should be read in conjunction
with the Company's periodic filings with the SEC. Technology
to Be Integrated With Internal Systems and Deployed to Scientists
in R+D
MOUNTAIN VIEW, Calif.pathology mitigation
In addition to
these banana disease tolerance data,
Senesco and Rahan have previously
shown both an increase in banana fruit shelf life and increase
in
growth rates of banana plants in field trials. The forward-looking
statements contained herein
are made only as of the date of this press
release, and the Company undertakes no obligation to publicly
update
such forward-looking statements to reflect subsequent events or
circumstances.pathology fungal
Eli Khayat
, the Scientific Director of Rahan stated, "These data
are encouraging and may lead to the achievement
of Rahan's major R+D
objective -- developing a 'Cavendish' banana with resistance to BLSD.regulated pests
"We
believe
that our technology can benefit the banana industry in a
variety of ways. Working to improve plant
varieties with cutting edge molecular
biology techniques, Rahan has developed protocols for over
200 plant
genera over the past 20 years.
Certain statements included in this press release
are
forward-looking statements within the meaning of the Private
Securities Litigation Reform
Act of 1995.nematodes regulated
The company
was founded in 1998 and is headquartered in Mountain View, California.weeds botany
"
The Ingenuity Pathways Analysis application makes use of the Ingenuity
Pathways Knowledge
Base, the world's largest curated database consisting of
millions of individually modeled relationships
between proteins, genes,
complexes, cells, tissues, drugs, and diseases.plant entomology
http://www.pests transduction
Health
/Medical Writers
NEW BRUNSWICK, NJ----Senesco
Technologies, Inc.
"This relationship
with Bristol-Myers Squibb creates the opportunity to
embed and extend the value of pathways analysis
in all areas of their R+D
pipeline," said Jake Leschly, Chief Executive Officer of Ingenuity Systems
.bacteria pests
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