, a leading provider
of databases, software and services in systems biology, announced today that
they have received a Phase I SBIR grant from the National Institute of General
Medical Science for development of methodologies intended for reconstruction
of functional networks affected in common human diseases. Because of this, the result
detected by 'genome scale ' technologies such as microarray gene expression,
proteomics and genotyping, is complex and multi -level.

synthesized phytochemistry

We will study
conditional perturbations of the human interactome assembled from manually
curated physical protein interactions and develop algorithms for assembly of
complete functional networks, from membrane receptors to transcriptional
factors and 'core effector' metabolic pathways .

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"Analysis of human biological networks is an exciting new area of systems
biology, and we are glad that our efforts are appreciated by the NIH," said
Dr. Each data type
provides only one level of information, and total reconstruction of the 'big
picture' of molecular pathology is a major challenge. GeneGo's
second product, MetaDrug(TM), is designed for medicinal chemists and enables
prediction of metabolites and their likely toxicity in human.

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In Phase I, GeneGo
will generate and test novel algorithms enabling comparison of disease related
OMICs datasets of different origin, based on networks topology and content.
Leaders from the American Soybean Association (ASA,) the National Corn
Growers Association (NCGA) and the National Cotton Council (NCC) are all
commemorating the planting of the billionth acre of biotech-enhanced
agricultural commodities in the world.

As such plant physiology bridges the gap between biochemistry and ecology.

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For more information, please visit the company's Web site at
http://www.com .

MetaCore(TM ), MetaDrug(TM) and MetaBase(TM) are trademarks of GeneGo, Inc.

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Physiology is concerned with the functioning of plants.

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JOSEPH, Mich. Craig Webb, a lab head at Van Andel and an advisor on the
grant.

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About GeneGo
GeneGo is a Michigan-based company developing systems biology technology
for life science research.) and relevant
active chemistry (metabolites, drugs, other xenobiotics) within the framework
of biological pathways and networks.

ADDITIONAL RESOURCES: Video, hard copy requests, contact information and
more available at http://www.

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ST. We believe that the integrated approach offered through GeneGo's
advanced computational systems will be critical in deciphering the key
molecular mechanisms of disease progression, and offer new diagnostic and
therapeutic strategies for the future advancement of molecular-based
medicine," said Dr.

This is largely interactions between plants and their environments.

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GeneGo's first product, MetaCore(TM),
assists scientists in the areas of target selection and validation,
identification of biomarkers for disease states and toxicology.

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Tatiana Nikolskaya, Chief Scientific Officer and President of GeneGo. This historic occurrence takes place
during this, the tenth year of commercial planting of biotech-enhanced crops .shtml

VIDEO PROVIDED BY: American Soybean Association

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GeneGo Is Awarded NIH Grant for Disease Network Algorithms

Farmers Recognize Planting of One-Billionth Acre of Biotech -Enhanced Crops

The benefits of these new crops include reduced pesticide use
and improved yields , which helps lower the cost of food and fiber production.

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We will test the approach on
disease datasets in collaboration with the Van Andel Research Institute.genego. During the last century,
world demand for food continues to rise and many innovations have helped
farmers defend against these pests.

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, GeneGo Inc.

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com/broadcast/21858/consumer.

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"
"We are truly excited at this opportunity to collaborate with the GeneGo
team.prnewswire.

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One of the most significant advancements
in agriculture has been seed-breeding programs that utilize plant
biotechnology.

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"Common diseases have profound effects on both signaling and metabolic
machinery, usually in more than one cell type. The Company's original computational platform
allows an integration and analysis of different kinds of experimental data
(mRNA expression, proteomics, metabolites, phenotypic data etc. Crop Biotechnology Has Increased Yield and Benefited the Environment

NEW YORK, As long as there has been farming, weeds
and insects have decreased agricultural output.

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