"
"Affinnova is clearly revolutionizing the NPD process. Its unique,
patent -pending technology uses genetic algorithms to "evolve" product
designs in response to consumer preferences . A complete list of the firm's 60 journals,
books, and newsmagazines is available at www.

memetics darwinian

3. Evolve SEQUENOM's corporate culture to be more responsive to market
needs.
* Create a sustainable competitive advantage by launching a series of
applications that significantly reduce cost per genotype beginning
with the iPLEX multiplexing assay.

Additional Cost Cutting Measures
SEQUENOM has also negotiated a rent deferral of approximately $3.

Web Cast of Conference Call
SEQUENOM's management will hold a conference call Thursday, September 15
at 9:00 a.

evolutionary memetics

Increased Operational Efficiency Expected to Deliver $7-9 Million Cash Flow
Savings for 2006; Includes a Headcount Reduction of Almost 30%

SAN DIEGO , SEQUENOM, Inc.2 million
over two years for its corporate headquarters in San Diego.m. These forward -looking statements
are based on current information that is likely to change and speak only as of
the date hereof. While retaining the
ability to inject vast amounts of consumer preference into the
process, teams can now explore and assess across such critical success
metrics as Year 1 Volume Potential, Year 1 Factory Sales Potential,
price sensitivity, competitive share impact and additional design
variations through a series of "what if" scenarios and analyses. For more information about
Affinnova, visit www. (www.

Sites about other views on origins of life, cosmic evolution, geological evolution and social evolution can be found in the relevant ODP categories.

domestication creationist

4. Future sales are expected to include higher value solutions such as
novel applications, assay technologies, kits and panels and value added
services. The Company is also
evaluating opportunities to license IP to more broadly enable the analysis of
nucleic acids by mass spectrometry.
Affinnova has supplemented IDEA -- which has been successfully
used by such consumer goods leaders as Procter + Gamble, Dannon and
Cadbury Schweppes to explore, optimize and evolve product concepts --
with two additional tools to assess additional competitive and
economic metrics: IDEA Validation and IDEA Simulation .

Second Alien Life Form May Exist on Earth States Report in Astrobiology Journal

Davies and Charles Lineweaver propose multiple scenarios for how a
second genesis of life could have occurred .

evolution arose

* Leverage proprietary biomarker content into valuable partnerships and
proprietary tests.

Broaden Core Technology in Genetic Analysis Research
SEQUENOM aims to transition to a higher growth and higher margin business
model. These results suggest that the Company can provide a
differentiated and competitive solution for effectively performing a broad
range of nucleic acid-based tests.

Cultural Transformation
SEQUENOM has a highly innovative capability.----

Growing industry adoption of IDEA(TM) Technology spawns new tools
for assessing market performance of new product concepts -- before
launch

Affinnova, Inc.Y.W.

Biological evolution through domestication, mutation and natural selection as initially presented by Charles Darwin .

darwinian cees

We expect to capitalize on our promising potential in
this large and fast growing market primarily through key strategic
partnerships.

Reduction of Staffing Levels
The Company has taken steps to reduce its headcount by almost 30% across
all departments, amounting to some 44 jobs in total and includes a voluntary
salary reduction by a member of executive management. The
Company is also taking steps to lower costs by reviewing its key supplier
relationships. will remain as Chief
Scientific Officer, and will continue to focus his efforts on external
strategic development.

com.

Business Editors/Technology Editors

WALTHAM, Mass.

Affinnova harnesses the voice of consumers to help companies
develop more successful brands and products. Affinnova's technology
has been adopted by a growing list of blue-chip customers including
eleven Fortune 500 companies .D.

darwinian evolution

Molecular Diagnostics
SEQUENOM views the molecular diagnostics opportunity as having significant
upside potential. In order to prosper, the
Company must transform to a business and market-driven organization. "The net result is that
Affinnova clients will come up with bigger ideas that are more likely
to succeed, in less time and often at less expense.com

About Affinnova , Inc.affinnova.

phylogeny creationism

SEQUENOM Announces Strategy to Unlock Growth Potential

Internally, operations and research and development
will implement improved processes designed to facilitate new product
introductions and better meet customer needs in a timely and efficient manner.sequenom.liebertpub. The Journal provides a forum for
scientists seeking to advance our understanding of life's origins,
evolution, distribution and destiny in the universe.

prebiotic songbirds

The
Company also plans to launch several new applications for use with its
MassARRAY system within the next year. To
accomplish this goal, the organization is recruiting several key leaders to
strengthen its research + development, operations, sales and marketing, and
business development activities. The system is able to deliver reliable and specific data from
complex biological samples and from genetic target material that is only
available in trace amounts.

Affinnova Introduces New Validation and Simulation Tools to Help Consumer Marketers Drive Product Innovation and Performance

Affinnova, IDEA, IDEA Validation and IDEA
Simulation are trademarks of Affinnova, Inc. "If the origin of life is
easy, a second example of life may lurk beneath our noses.

arose cambrian

* Expand the use of our platform and drive future new sales through
innovative applications such as QGE, methylation and single mutation
discovery. Importantly, the MassARRAY solution and future
applications developed for addressing opportunities in the research market
should apply to molecular diagnostic applications.

arose songbirds

* Offer products and services that capture more of the value chain and
offer powerful and quality solutions to our customers, including
quantitative gene expression (QGE) and methylation services.
Upon the anticipated fourth quarter departure of the present Chief Financial
Officer, the Company's current Vice President of Finance , John Sharp, CPA, is
expected to be appointed by the Board of Directors and assume the role of
principal financial and accounting officer for the Company. With the
new validation and simulation abilities , Affinnova has given NPD teams
exactly what they need to apply this revolution to their business , "
said Jim Findley, principal of Findley Associates LLC and formerly
executive vice president of analytic product management and
development at Information Resources, Inc.
"New product success or failure is most often set in motion early
in the development process, with limited customer involvement at the
critical decision points," concluded Andonian.

Business Editors

NEW ROCHELLE , N.

cees darwinian

Reduce operating expenses and increase organizational effectiveness. The Company may utilize key partnerships
and license third party IP in order to further develop and commercialize the
platform for molecular diagnostics. Their collective feedback contributes to the
evolution of the "fittest " designs and concepts -- those most likely
to win market share in crowded and competitive market landscapes.

"
Astrobiology is an authoritative peer-reviewed journal published
bimonthly in print and online.

cambrian domestication

The strategy focuses on unlocking growth in its
core genetic analysis business and leveraging its MassARRAY(R) technology and
strong intellectual property (IP) position for analyzing nucleic acids by mass
spectrometry.newscom. Charles Cantor, Ph.com/event.

hierarchies refuting

"In
parallel, SEQUENOM has prioritized key product and service initiatives that,
in due course, are expected to drive growth and create value. Together, the
three products create an integrated innovation platform to offer
brand, product and marketing teams a highly nuanced assessment, not
only of consumer choice drivers and attribute preferences, but of
purchase intent; uniqueness; liking; stated transaction size; and
probable purchase frequency.
IDEA Validation and IDEA Simulation in turn subject these designs
to a variety of economic and competitive metrics, supporting
consumer-driven strategic and tactical decisions.----If life
readily emerged on Earth shortly after conditions became favorable,
isn 't it likely that other genesis events also occurred, creating
additional "alien" life forms that co-exist with known life, asks a
groundbreaking hypothesis paper in the April 2005 (Volume 5, Number 2)
issue of Astrobiology, a peer-reviewed journal published by Mary Ann
Liebert, Inc.liebertpub ., is a privately held, fully integrated
media company known for establishing authoritative peer-reviewed
journals in many promising areas of science and biomedical research.

evolutionary evolution

(Nasdaq: SQNM) announced today a corporate restructuring plan to position the
Company for long-term growth.
(Logo: http://www.D.

Except for the historical information contained herein, the matters set
forth in this press release, including without limitation statements regarding
the Company's restructuring plan, the lease payment deferral, the anticipated
reduction of ongoing operating expenses and the expected restructuring costs,
securing an improved financial position, statements regarding the elimination
or consolidation of certain positions, increased organizational effectiveness,
potential long -term growth, potential expansion of and growth in the Company's
genetic analysis business, the strengths of the Company's iPLEX multiplexing
assay, the development of potential new applications for the MassARRAY system,
and the Company's ability to expand its customer base, introduce
cost-effective , differentiated and competitive solutions, and its ability to
be more responsive to market and customer needs, recruit key employees, pursue
opportunities in the genetic analysis and molecular medicine markets, raising
capital, accessing financial markets and advancing strategic partnerships, are
forward -looking statements within the meaning of the "safe harbor" provisions
of the Private Securities Litigation Reform Act of 1995.

hierarchies nearctica

The MassARRAY solution with expanded
applications and novel biomarkers is closely integrated with the upside
potential anticipated from molecular diagnostic opportunities. Secure an improved financial position.D. EDT to discuss the Company's strategic update. For more information , please visit our website at
http://www. The paper is available free online
at www.C.
"Davies and Lineweaver consider a way to cut the anthropic knot,"
says journal Hypothesis Papers editor, Norman H. A complete table
of contents and a full sample issue may be viewed online at
www.

arose domestication

* Introduce a cost effective MassARRAY solution for lower throughput
users.

Secure an Improved Financial Position
The steps listed above are undertaken to strengthen SEQUENOM's financial
position. The web
cast will be available online through September 30, 2005 . "Affinnova's extension of the IDEA
platform into the crucial areas of market validation and competition
now provides consumer marketers even richer insights -- coupling a
rich understanding of the consumer landscape with key business metrics
for better decision-making.com).

phylogeny evolutionary

"Currently, we are in the process of stabilizing the core genetic analysis
business and focusing on initiatives with high growth prospects," said Harry
Stylli, Ph.
* Develop multiplexed quantitative methylation and multiplexed QGE for
fine mapping and molecular diagnostics.0 million related to severance and other related costs. However, it is likely that the Company will consider additional
steps to raise capital including accessing financial markets and advancing
strategic partnerships.

arose recasting

SEQUENOM intends to expand its genotyping business by
capitalizing on the strength of its iPLEX(TM) multiplexing assay, which
substantially reduces the cost per genotype in fine mapping studies.com/cgi-bin/prnh /20040415/SQNMLOGO )

The strategy has four key components:
1. New QGE and methylation applications support, amongst other keys
areas, cancer research. In addition,
SEQUENOM continues to explore subleasing options for this facility. A live web cast is
available at http://www.sequenom ., which harnesses the principles of genetic
evolution to optimize concepts, products and brands for
consumer-focused companies, today announced two new extensions of its
widely adopted IDEA(TM) (Interactive Design by Evolutionary
Algorithms) technology. IDEA
enables product and marketing teams to improve product success rates
by placing the consumer at the heart of product and brand development,
exploring such concept innovation drivers as feature interaction
effects, consumer choice/feature drivers and relative attribute
preferences to generate optimized leading designs.

"The extended Affinnova
IDEA platform we are introducing today is aimed at reducing the rate
of new product failure by injecting broad consumer input into the
earliest stages of design and market opportunity assessment."

Availability

For more information about Affinnova's IDEA(TM) platform, call
(781) 464-4700 or email info@affinnova.
How then to detect a "second sample," and is there evidence for
"alien life" on Earth? Davies, from the Australian Centre for
Astrobiology at Macquarie University (New South Wales), and
Lineweaver, from the Planetary Science Institute at the Australian
National University, conclude that life is likely to have emerged on
Earth more than once and, although there are ways to obtain evidence
of alien life, these microorganisms could exist on Earth today and
remain undetected.,
Professor in the Departments of Geophysics and Geological and
Environmental Sciences, Stanford University.com/ast
Mary Ann Liebert, Inc.

prebiotic songbirds

Favorable results have been generated in the benchmarking
study collaboration with Siemens Medical Group using SEQUENOM 's MassARRAY
Compact system. Gaining cost effective access to
proprietary biomarkers through our key collaborators will support this effort.

SEQUENOM(R), MassARRAY(R) and iPLEX(TM) are trademarks of SEQUENOM, Inc.

hierarchies extinctions

, SEQUENOM's President and Chief Executive Officer.com.com/ast
In "Finding a Second Sample of Life on Earth," authors P.liebertpub.liebertpub.

domestication extinctions

Leverage SEQUENOM's strengths and ultimately unlock growth in the
genetic analysis and the molecular diagnostics markets.
2.

This reduction also
eliminates the Company's Chief Medical Officer position and consolidates the
Company's Chief Financial Officer and Vice President of Finance positions. During the third
quarter , SEQUENOM expects to take a pre-tax charge of approximately
$1.asp?id=30516 and through a
link that is posted on the Company's website at http://www. A telephone replay
of the conference call also will be available for 48 hours at (800) 642-1687
or (706) 645-9291, reservation # 9571041.

nearctica recasting

The Company's proprietary
MassARRAY system is a high-performance DNA analysis platform that efficiently
and precisely measures the amount of genetic target material and variations
therein. Other trademarks are the
property of their respective owners.

replicators songbirds

"

Business Strategy
* Focus on meeting customer needs in the fast growing fine mapping
segment of the $300 million genetic analysis market and add additional
pharmaceutical, biotechnology, veterinary, and molecular diagnostic
companies to our research customer base.
New business development and sales and marketing efforts will concentrate on
leveraging SEQUENOM's assets in the genetic analysis research market and
explore opportunities in the molecular diagnostics market.

About SEQUENOM
SEQUENOM is committed to providing the best genetic analysis products that
translate genomic science into superior solutions for biomedical research,
molecular medicine and agricultural applications. These forward-
looking statements are subject to risks and uncertainties that may cause
actual results to differ materially, including the risks and uncertainties
associated with the Company's ability to implement the restructuring plan to
the extent currently anticipated, possible changes in the size and components
of the operating expense reductions, the impact of personnel reductions on
product development efforts, the company's ability to project accurately cost
savings and general economic conditions, and the risks and uncertainties
associated with developing and commercializing any new technology or products,
pursuing new potential markets and executing on a business strategy, and other
risks detailed from time to time in the Company's SEC filings, including the
Company's Annual Report on Form 10-K for the year ended December 31, 2004, and
most recent Quarterly Report on Form 10-Q. Affinnova is privately held and
headquartered in Waltham, Massachusetts. Given that existing life
formed under early Earth-like conditions, then logically it would seem
possible for alternative life to have formed on Earth in a similar
manner and to have survived to the present day. Sleep, Ph. We have the
technology to commence our search.
Its biotechnology trade magazine, Genetic Engineering News (GEN), was
the first in its field and is today the industry's most widely read
publication worldwide.

zeeman hierarchies

Further,
SEQUENOM's core technology is demonstrating emerging utility in the molecular
diagnostics market.
Reduce operating expenses and increase organizational effectiveness
SEQUENOM is taking a series of actions that should contribute to a $7-9
million reduction in 2006 cash burn.videonewswire.
"Dozens of global brands have used Affinnova's IDEA technology to
better understand the subtle synergies between concept features and
attributes, to allow thousands of consumers online to explore large
and complex design spaces, and to develop stronger concepts reflecting
the complex nuances of consumer preference," said David Andonian,
Affinnova chairman and CEO."

Validation and Simulation

Affinnova's patent pending IDEA(TM) technology allows hundreds or
thousands of consumers to interact with holistic designs and concepts
via the Internet.com

(C)2005 Affinnova Inc.com

refuting songbird

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- - kjjkjk

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