Axsun NIR IntegraSpec(TM) Analyzer Wins R+D 100 Award

Based on a
miniature NIR spectrometer platform with a tunable laser-based light source,
integrated wavelength and amplitude references, and detector, semiconductor
manufacturing techniques produce a uniform product, ensuring rapid calibration
transfer from instrument to instrument ."
Axsun's IntegraSpec Analyzers are in worldwide use by companies in the
pharmaceutical, petrochemical , oil and gas, and other industries where
utilization, yield and safety are paramount concerns.

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In this role, he helped create and implement strategy for a
business unit with an annual $10 billion revenue stream.
The result is that many pharma and biotech companies have reconfigured
their research models to incorporate biomarker functionality.

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. Additionally, they help enable the
creation and rapid provisioning of new revenue-generating services.
The new development program will see the launch of multiple
biomarker products to form a robust and scalable solution for the
analysis of mass spectrometry and capillary electrophoresis trace
data.
John Spreadbury, Group Sales and Marketing Director of Nonlinear
Dynamics, and CEO of Nonlinear USA Inc, commented: "The fields of drug
discovery , biomedical research and pharmacogenomics are developing
around the use of biomarkers in accordance with new FDA guidelines.

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The near-infrared portion of
the spectrum is particularly useful for solids and liquids analysis in
the pharmaceutical and agricultural products industries. He has also worked closely with Telcordia
and the ITU to integrate new technologies into both the standards and
operations elements of the organization, and possesses a relevant
patent in this area. This will incorporate a range of new powerful analytical tools
for biomarker discovery, predictive modelling and data processing .

infrared spectroscopic

Described as "the
Oscars of Invention" by The Chicago Tribune, the prestigious R+D 100 Awards
have been recognizing excellence in innovation for 42 years.axsun.. Over his
10-year career in telecommunications , Ramani has been instrumental in
helping carriers refine technology decisions, business cases, and
optimize many of the long haul and metropolitan area networks in North
America, Europe and Japan .com

spectroscopic molecule

Axsun has
applied its expertise in micro-optics and precision engineering to pioneer an
entirely new class of fully functional, miniaturized spectroscopic instruments
and devices that enable dramatic improvements in quality, productivity, and
performance across a variety of industries -- from pharmaceutical
manufacturing, high-speed industrial process control, and
chemical/petrochemical processing, to medical devices and diagnostics,
forensics, and scientific discovery.7 billion worldwide and has participated in numerous merger and
acquisition transactions. By applying multiple
data -handling and visualisation options, users can identify and review
data from multiple markers with increased confidence.

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The award, selected by an independent panel of judges and the editors of
R+D Magazine, "provides a mark of excellence known to industry, government,
and academia as proof that the product is one of the most innovative ideas of
the year," explained the magazine's Editor -in-Chief, Tim Studt.

Investigate ways to make chemical-sensing measurements more
efficient by using a technique that allows a complete spectrum
to be collected with a single detector using a time sequence
of filter patterns;

Discuss how using diffractive-based and mirror-based MEMS
microfabrication techniques can provide a full spectrum
measurement with no moving parts; and

Examine diffractive MEMS devices and their applications in
chemical spectroscopy.
Nonlinear sells and supports its products through its UK headquarters,
its USA office, and its global network of partners and OEM resellers.

molecule hardcopy

The conventional method of performing chemical identification is
to measure the entire spectrum of transmitted light across some
pre-selected range of wavelengths, and then to analyze the spectrum to
identify characteristic absorption lines of target chemicals. He has closed sales contracts worth over
$1.

characterisation vibrations

A MEMS chip is one way to meet
all these requirements, as it can be used to create various patterns
of "off-on " filters, passing some bands, blocking others. For more information, visit
www. This will incorporate a range of adaptable analysis
features to import, analyse and identify individual and multiple
markers from trace samples.

Infrared spectroscopy is a technique used in molecular bond identification and characterisation , where atomic vibrations and rotations are exploited to produce a spectrum.

nir unknowns

, a
leading manufacturer of micro-optoelectronic products that improve quality,
performance, and productivity in a variety of industries, has been notified
that the Axsun NIR (Near Infrared) IntegraSpec Analyzer has been selected as
one of the 2005 Top 100 new products by R+D magazine. For more information, visit
http: //www. Set for launch
in Q3 2005, Phoretix Biomarker represents a highly usable and flexible
software solution for entry level trace data analysis and
visualisation.

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South East Corner of the Exhibition Hall
Orange County Convention Center

Why

Every molecular species has a unique pattern of optical absorption
which can be measured by a spectrometer. Phoretix Biomarker further extends these
capabilities with powerful neighbour joining and UPGMA hierarchical
clustering algorithms .

coupled biosensors

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Who and What

Next week at PittCon 2005, Mouli Ramani, Polychromix vice
president of marketing and business development, will discuss how
Micro-Electro-Mechanical Systems (MEMS) technology can be applied to
spectroscopy. His session, titled "A Revolutionary Approach to NIR
Spectroscopy Based on Diffractive MEMS technology" will:

Explore the concept of optical spectroscopy as used in a MEMS
chip, creating a compact and versatile chemical analysis
system at a disruptive low cost."
The first release from this development program will be a medium
throughput analysis tool aimed at the academic market.

spectra absorption

IntegraSpec Analyzer products address a broad range of NIR spectroscopic
process applications, monitoring vapor, liquids, and solids.

About AXSUN Technologies
Axsun Technologies, Inc. Marker data can
then be queried, validated and classified via a range of database
options.

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BILLERICA, Mass. This is achieved through an automated m/z
picking algorithm to distinguish particular peaks of interest, while
eliminating sample 'noise '."

About Nonlinear Dynamics Ltd

Established in 1989, Nonlinear Dynamics is a leading worldwide
provider of bioinformatics solutions to the life science industry.

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m.
"In developing a new biomarker range, Nonlinear is applying its
considerable experience and expertise in mining and analysing data
from multiple applications.

widener molecule

"Our NIR IntegraSpec Analyzers enable manufacturing companies to take NIR
methods out of the lab and use them in the process environment," explained
Jack Kay , Axsun's President and CEO. One goal
of modern instrumentation is to make such chemical-sensing
measurements more efficient with respect to speed, the use of
available light energy from the source, and cost , for example by using
a single detector rather than an array.
Carriers can dynamically provision and control optical channels
remotely from a network operating center, effectively replacing "truck
rolls" (sending out maintenance trucks) with "key strokes" (entered at
a network operating center terminal).polychromix. Our outstanding technical portfolio
underlines the adaptability of our development processes to construct
an innovative and targeted research platform specifically aimed at
biomarker discovery.

pca visualisation

About Polychromix

Polychromix, a privately held advanced optical networking
technology company headquartered in Wilmington, Massachusetts, offers
modular optical subsystems based on an innovative core technology
platform that enable dynamically re-configurable optical networks .

molecule pca

com.

Pharmaceutical Writers/Business Editors/Biotech Writers/Health
Editors
BIOWIRE2K

NEWCASTLE-UPON-TYNE, England----April 13,
2005--Nonlinear Dynamics Ltd, a leading provider of bioinformatics
solutions, today announced it has undertaken a large scale development
program to evolve a new biomarker discovery product range. This represents a considerable improvement over single marker
statistics, and a breakthrough for any lab conducting biomarker
discovery.

raman spectroscopy

Kay continued, "For most manufacturing
companies today, the full capabilities of NIR spectroscopy are simply not
available in the process chain. They have to either take samples to the lab,
or use reduced functionality solutions on-line. Axsun's NIR IntegraSpec
Analyzer is the bridge, allowing companies to quickly prove the usefulness of
NIR in the lab, before moving the method to the production floor.
Polychromix's suite of Channel Management Solutions addresses the
capital and operating expense challenges that both carriers and
network systems vendors face.

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, Axsun Technologies , Inc. IntegraSpec micro-
spectrometers give companies the best of both, laboratory performance, with
the ruggedness and reliability of an on-line sensor.

Assignment Desks/High-Tech Editors
Pittcon 2005
REMINDER.
Philippe Bogard, Strategic Marketing Manager of Nonlinear
Dynamics , added: "Single protein biomarkers with clinically relevant
predictive power are very rare and often lack the sensitivity and
specificity required for effective research.

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ORLANDO, Fla.

About Mouli Ramani

Prior to joining Polychromix, Mouli Ramani served as vice
president of strategic marketing in Nortel Networks' Optical Networks
division. However
at present, widespread implementation of this technique is hampered by
the lack of accurate, hardware independent software commercially
available to researchers.

biosensors vibrations

REMINDER...Polychromix Educates Attendees at the Pittsburgh Conference on Applying MEMS Technology to Spectroscopy Applications

When and Where

Wednesday, March 2, 2005
1:30 to 3:30 p. The
Company's innovative product portfolio comprises high-quality analysis
and data mining tools for 1D and 2D electrophoresis gels and
microarrays, the core technologies of genomics and proteomics.

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, established in 1998, develops and manufactures
advanced components and photonic subsystems used in test and measurement
applications, and throughout the world's communication networks. Ramani holds a degree in computer engineering
from the Royal Military College of Canada and a master's degree from
Duke University. Spectra can be visualised using a variety
of different graphical formats, including stacking and spectral
overlay, as well as simulated gel maps. Comparative visual analysis
across multiple samples enables rapid discovery of disparate features
for later identification.

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Spectroscopy
is widely used in a broad variety of applications from laboratories to
industrial process control such as material identification,
quantitative analysis, quality control, and material inspection.

Nonlinear Dynamics Plans to Enter Biomarker Discovery Market with New Software Analysis Solution

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