is a subsidiary of DFB Pharmaceuticals Inc.phytonbiotech.reedbusiness.com), the largest business-to-business publisher in the
U.

Agricultural , environmental, materials, QA/QC, and forensic links would be some of the most noted topics falling into this category.

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, a DFB Pharmaceuticals affiliate, has announced that
Phyton Biotech's headquarters will move to Princeton, New Jersey, in fall 2005
and that the company has significantly expanded its research and development
leadership team. The improved
resolution obtained by LC-MS provides more accurate molecular weight of the
larger oligonucleotides.

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FORT WORTH, Texas, Magnus Precht , President of
Phyton Biotech, Inc. Phyton's
website is http://www.

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Horn
will head the strain development, cryopreservation , and plant cell and
molecular biology departments.

Phyton Biotech, Inc. Its German subsidiary, Phyton GmbH, operates the world's largest
commercial cGMP manufacturing facility for plant cell fermentation.
With the integrated Novatia LC-MS system, Sigma-Genosys is able to obtain
high quality mass analysis of larger oligonucleotides.

The LC-MS system by Novatia along with their methods and their automated
post-analysis software provides Sigma-Genosys with a high throughput (one
sample per minute) LC-MS technique for the analyses of larger
oligonucleotides. The addition of the
Novatia LC-MS system ensures that customers are provided with the highest
possible quality oligonucleotides and peptides. Sigma-Aldrich operates in 35 countries and has over 6,800
employees providing excellent service worldwide.

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Phyton Biotech Adds Three to Scientific Team Will Move Headquarters to Princeton in Fall

Dr.com )., ReedLink
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While at Pittcon, ReedLink conducted a user survey that asked science
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Precht explained that the move and expansion of personnel reflect the
company's plans to expand its activities beyond the current primary focus --
the production of paclitaxel, the active ingredient in TAXOL(R)*, one of the
leading drugs for the treatment of cancer.
"The addition of these scientists to the Phyton R+D team will be key to
Phyton's extension of its technology to the production of transgenic proteins
while strengthening our current small molecule production capabilities," said
Charles Swindell, PhD, Vice President of Research and Development.

About ReedLink
ReedLink (http://www., offering business professionals in the media, manufacturing,
electronics, construction and retail industries more than 100 market-leading
business-to-business publications, 75 Webzines and Web portals, custom
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"Our move to Princeton will place us at the
epicenter of our industry as we continue to advance our position in
biotechnology. Dr. Dr. Over one million scientists and technologists use
its products.

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4 billion Life Science and High Technology
company, has incorporated into its quality control (QC) lab an LC -MS system
from Novatia (Princeton, NJ; http://www.
The Novatia system also provides Sigma -Genosys with the ability to obtain
higher quality mass spectra data in a high throughput format.

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Traditionally, larger synthetic oligonucleotides are analyzed by capillary
electrophoresis and by PAGE analysis. When molecular weight information is
needed, MALDI-TOF mass analysis is carried out. Here are some of the findings: Ninety percent of
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Scientists joining Phyton include:
* Michael Horn, PhD, Director of Cell and Molecular Biology.

* TAXOL is a registered trademark of Bristol -Myers Squibb Company.com . RBI is a member
of the Reed Elsevier Group plc (NYSE: RUK and ENL) - a world-leading publisher
and information provider operating in the science and medical, legal,
education and business-to-business industry sectors.

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Precht.
* Guillermo Tous, PhD, Director of Chemistry .

Sigma-Genosys Enters Agreement With Novatia

LOUIS, Sigma-Genosys, a division of
Sigma-Aldrich (Nasdaq: SIAL), a $1.

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Phyton's
proprietary plant cell culture technology platform is used to develop and
manufacture products with applications in the pharmaceutical and biotech
industries.
Sigma-Genosys has continued to examine and implement cutting edge
technologies for continued improvement in product quality. The Company is committed to
accelerating Customers' success through leadership in Life Science, High
Technology and Service.

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* Sarad Parekh, PhD, Director of Cell Culture Process Development.
DFB Pharmaceuticals Inc., an outsourcing service
organization to the pharmaceutical industry, and DFB Bioscience, focusing on
cell based therapeutic research and development . Visit http://www. The system improves
the molecular weight determination of larger synthetic oligonucleotides (>50
bases) as well as synthetic peptides. Novatia specializes in developing an
integrated system encompassing hardware, software, method development and
automated data analysis. Traditional LC-MS
techniques can be time consuming and not amenable to high throughput analysis.
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This is due
primarily to poor ionization of the large oligonucleotides.

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"Over 62,000 people are engaged in the life sciences sector in New
Jersey," said Mr. The well -integrated instrument and protocols developed by
Novatia reduced the IOQ (installation/operating qualification) time to days
from the weeks normally associated with high-technology analytical systems .

About Sigma-Aldrich: Sigma-Aldrich (Nasdaq: SIAL) is a leading Life
Science and High Technology company. ROCKAWAY, N.

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Tous will lead
Phyton's analytical chemistry, chemical development, and media
formulation departments.reedlink.com) is owned by Reed Business Information
(http://www.

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Parekh will lead Phyton's process development and pilot plant
departments. and Coria Laboratories, Ltd.dfb.com/sales.

Pure and applied methods development for analytical processes are also included.

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, both branded
marketing organizations, DPT Laboratories, Ltd.

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"
Mr.enovatia. Traditional MALDI-TOF MS
analysis while rapid (<5 seconds per sample) and relatively simple, provides
inadequate mass spectra data if any, for larger oligonucleotides . For more information, visit sigma-aldrich.