com

thermochemistry 793

S.S.S.8 million in cash in exchange
for the relevant assets. QIAGEN employs more than 1,500 people worldwide. Further
information on QIAGEN can be found at http://www.

thermodynamic raman

The architectural
structure of fullerene molecules resembles the geodesic domes created
by architect and philosopher R.
The Frontier Carbon Corporation was established in Japan in
December 2001 as a joint venture of the Mitsubishi Chemical
Corporation and Mitsubishi Corporation with the goal of becoming the
world leader in the commercial production of nano-scale carbon
products.

A wave of research and development activities all over the world
has led to almost 2,000 application -oriented patents, spanning a very
broad range spectrum of potential commercial applications, including:
anticancer drug delivery systems using photodynamic therapy, HIV
drugs, cosmetics to slow down the aging of human skin, longer-life
lithium ion batteries, electrolyte membrane for fuel cells,
superconductive materials, highly functional coatings, nano-composite
polymers with desirable mechanical, thermal, electromagnetic, and/or
optical properties, and ultra-fine crystalline artificial diamonds for
drilling and industrial polishing. A typical LC-MALDI protocol consists of sample purification ,
enzymatic digestion, separation of peptides by LC and identification of
proteins by peptide mass fingerprint.
The acquisition of the bioanalytical business of SuNyX expands on a
previous licensing arrangement. QIAGEN anticipates that the
transaction will add approximately US$1 million in net sales and will have a
slightly dilutive impact of approximately US$0.

raman electrolyte



3. Mitsubishi Chemical Corporation, which owns worldwide patent
rights on advanced technologies for the purification of
fullerenic products, and production of a large variety of
chemically functionalized fullerenes.
The combination of the acquisition of the bioanalytical business of SuNyx
GmbH with the acquisition of key assets of LCI (announced today in a separate
press release ) creates a complete, proprietary and technology-leading
portfolio for QIAGEN in the rapidly growing market segment of sample
preparation of proteins and peptides for analysis using MALDI Mass
Spectrometry . QIAGEN expects to provide
further details on the acquisitions announced on August 1 in its upcoming
conference call reporting the financial results of its second quarter 2005 on
August 9, 2005.
V. Such
uncertainties and risks include, but are not limited to, risks associated
with management of growth and international operations (including the effects
of currency fluctuations and risks of dependency on logistics), variability
of operating results, the commercial development of the applied testing
markets and proteomics markets, nucleic acid-based molecular diagnostics
market , and genetic vaccination and gene therapy markets, competition, rapid
or unexpected changes in technologies , fluctuations in demand for QIAGEN's,
products (including fluctuations for certain events including funding,
budgets, and others), difficulties in successfully adapting QIAGEN's products
to integrated solutions and producing such products, the ability of QIAGEN to
identify and develop new products and to differentiate its products from
competitors, market acceptance of QIAGEN's new products and the integration
of acquisitions of technologies and businesses.

descriptors 793

Mitsubishi Corporation and Mitsubishi International Corp.
MALDI Mass Spectrometry has become the most important analytical tool in
the identification of proteins and evaluation of their role in biological
processes in the areas of proteomics, drug discovery, and biomarker
identification. This simplifies and standardizes the
LC MALDI procedure. Subject to the terms of the acquisition
agreement, QIAGEN will pay approximately US$0.
The company has developed and launched innovative bioanalytical solutions
with the MPep and MProtChip(R) platforms which are delivered to leading
pharma, biotech and academic laboratories worldwide.
Certain of the statements contained in this news release may be
considered forward -looking statements within the meaning of Section 27A of
the U. To the extent that any of the
statements contained herein relating to QIAGEN's products, markets, strategy
or operating results are forward -looking, such statements are based on
current expectations that involve a number of uncertainties and risks.

esis thermophysical

An additional consideration of approximately US$0., a Netherlands holding company with subsidiaries in Germany,
the United States, Japan, the United Kingdom, Switzerland, France, Italy,
Australia , Norway, Austria, Canada, Sweden, and the Netherlands believes it
is the world's leading provider of innovative enabling technologies and
products for the separation, purification and handling of nucleic acids and
proteins.

crystallographers 60000

Their discovery
was recognized with the 1996 Nobel Prize in chemistry .7%
Mitsubishi Corporation 23. QIAGEN has developed a comprehensive portfolio of more than 320
proprietary, consumable products for nucleic acid and protein separation ,
purification and handling, nucleic acid amplification, as well as automated
instrumentation, synthetic nucleic acid products and related services.S.


thermodynamic spectroscopic

Other
relatively common fullerenes are C70, C76, and C84.

4. These products allow examining
new dimensions in sample preparation by leveraging unique,
nanotechnology-based surface structures.
SuNyx has developed a technology platform which enables researchers to
significantly reduce the number of pre-analytical steps and increase
sensitivity at the same time by measuring each LC-fraction on a ready-made
chip with pre-deposited matrix spots on ultraphobic surfaces.
"The acquisitions of key assets of LumiCyte and of the bioanalytical
assets of SuNyx position QIAGEN as the leading provider for standardized ,
on-chip sample preparation in the rapidly growing field of MALDI and LC-MALDI
Mass Spectrometry for protein analysis," said Peer M.

solubility experimentally

in March
2005 in co-operation with TDA Research, Inc.
The new U.

2.f-carbon."
About QIAGEN:
QIAGEN N.
Securities Exchange Act of 1934 , as amended.

793 thermochemistry

S. Mitsubishi
Corporation also has an exclusive license of a fullerene
material patent in certain countries from Fullerene
International Corporation, a U.

spectroscopic thermophysical

for serving present and
potential customers.
By far the most common fullerene is C60, also known as
"buckyballs," which look like soccer balls - round, hollow molecular
cages of carbon atoms about a billionth of an inch in diameter." Frontier Carbon Corporation America will offer a
range of products: Nanom Mix (mixed fullerenes, including C60 and
C70); Nanom Purple (pure C60); Nanom Spectra (tailor -made, chemically
functionalized fullerenes); and mixtures of fullerenic materials with
unique properties., a U.0%
Nanotech Partners 26.8
million is subject to certain milestones.qiagen.

electrolytes iupac

Some products using fullerenic materials are already
commercialized in Japan, for example coatings for bowling balls, fiber
reinforced composites for badminton rackets , tennis rackets, and golf
club shafts, lubricants for car air conditioners and coatings for
glass . customers of fullerenic products, FCCA
has established an effective network of business agreements with
various corporations, including:

1. Schatz, QIAGEN's Chief
Executive Officer.
"SuNyx products are highly complementary to LumiCyte's
technology portfolio and complete QIAGEN's solutions for application-specific
sample preparation for MALDI-based protein identification and analysis.

webbook desorption

Fullerenes are extraordinarily stable and heat-resistant,
joining diamonds and graphite as the third form of pure carbon, yet
are the only form of carbon that is soluble, leading to easy
processing and a variety of chemical modifications for usable
nanotechnology materials.,
which offer a large network for the worldwide marketing and
sales of fullerenic materials , and the development of novel
nanotechnology products based on fullerenes.S.


Company Profile

Frontier Carbon Corporation America

(1) Establishment: December, 2004

(2) Company name: Frontier Carbon Corporation America

(3) Location of head office: c/o Mitsubishi International Corp
655 Third Avenue, New York, NY 10017, USA

(4) Investment ratio : Frontier Carbon Corporation 100%

(5) President: Shigeki Tomonoh

(6) Contact 212-605 -2151


Frontier Carbon Corporation

(1) Establishment: December, 2001

(2) Company name: Frontier Carbon Corporation

(3) Location of head office: 1-8-7 Kyobashi Chuo-ku,Tokyo,104-0031
Japan

(4) Capital 53M US dollars (5,300,000,000 Yen)

(5) Investment ratio : Mitsubishi Chemical Corporation 51.
SuNyx's MPep and MProtChip(R) platforms can be used on most major MS
instruments suitable for LC-MALDI. For further information,
refer to the discussion in reports that QIAGEN has filed with , or furnished
to, the U.

chime 60000



Business Editors/Chemicals Writers/Manufacturing Writers

NEW YORK----To meet the growing
commercial demand for nano-scale products in the United States and
Europe , Frontier Carbon Corporation (FCC) of Tokyo, Japan, has
established Frontier Carbon Corporation America (FCCA) in December
2004 to begin production of fullerene materials in the U. Buckminster Fuller.
market.
To serve the potential U. corporation.3%

(6) President: Shigeki Tomonoh

(7) Contact: +813-5159-6880
URL: http://www. Unfortunately , this approach often has
limitations in identification of low abundant proteins, which are of the
highest interest. Securities Act of 1933, as amended, and Section 21E of the U.

syntheses experimentally

Nanotechnology News: Japan's Frontier Carbon Corporation to Manufacture in U.S. -- Will Accelerate Production of Fullerenes for Nanomanufacturing

corporation will market fullerene products under the
brand name "Nanom . Honjo Chemical Corporation, a Japanese company producing
fullerenic materials through the arc-based method.S.

electrolyte maldi

FCC started
delivering Fullerene samples at prices 10 times lower than those
prevailing in the market in February 2002.

thermodata spectroscopic

5 million on QIAGEN's net
income in 2006 and will be accretive thereafter.
QIAGEN's products are sold in more than 42 countries throughout the world to
academic research markets and to leading pharmaceutical and biotechnology
companies. In addition , QIAGEN is positioning its products for sale into
developing commercial markets, including applied testing markets, clinical
research, nucleic acid-based molecular diagnostics, and genetic vaccination
and gene therapy. Securities and Exchange Commission (SEC).

munir raman


With world-class production technologies , unique intellectual
property and the highly effective global sales forces of its parent
companies , Frontier Carbon Corporation in 2003 began operating a 40
tons per year commercial-scale, low-cost plant producing fullerenes,
which had been difficult to achieve by previous methods. The MPep and MProtChip(R)
technology provides inherent confinement of defined volumes of sample drops
resulting in precise fraction collection from the liquid chromatography run,
even under high throughput conditions .

spectroscopic iupac

V.
About SuNyx GmbH:
SuNyx is a German-based private company with activities in Bioanalytics
and Optical Coatings based on its proprietary know-how with respect to
precise control of material properties using nanoscopic surface structures.

chime thermophysical

corporation licensed by
Massachusetts Institute of Technology to use combustion-based
technology for the production of fullerenic products . We
are observing an increasing interest in the analysis of low abundant
proteins, which seem to play significant roles in cell regulation processes.

electrolyte raman


Fullerenes are large carbon molecules with unique properties that
are particularly well suited to nanotechnology-based applications and
have led to prototyping a large number of promising cutting-edge
products.

QIAGEN to Acquire Bioanalytical Assets From SuNyx GmbH

"On-Chip," Nanotechnology-Based Sample Preparation for LC-MALDI Mass
Spectrometry

VENLO, The Netherlands, QIAGEN N.

descriptors infochem


To date more than 400 Japanese companies have purchased sample
lots and are developing commercial products with unique
characteristics. This brings to
customers a highly efficient sample preparation tool to analyze proteomes
and, in particular, low abundant proteins. The optimized pre-deposited matrix spot leads to an up to
100-fold increased sensitivity due to on-chip pre-concentration effects. "Teaming up with QIAGEN, the world's
leading provider of enabling technologies for pre-analytical sample
preparation in life sciences will allow SuNyx to further grow its technology
and explore additional value-adding opportunities.S.

thermodynamic electrolytes

com.

60000 experimentally

In addition, FCCA will pursue exclusive business
agreements with select customers for the expeditious development of
nanotechnology-based products, offering to the customers its years of
experience in the development of such products for the U.S. SuNyx
has developed and recently initiated marketing of its proprietary MPep and
MProtChip(R) platforms for sample preparation of peptide and protein samples
for analysis on Liquid Chromatography (LC)-MALDI (Matrix-Assisted Laser
Desorption/Ionization ) Mass Spectrometry (MS).
The ease of use and the nanotechnology-based, on-chip concentration features
make SuNyx MALDI chips a perfect pre-analytical tool for high sensitivity
LC-MALDI Mass Spectrometry ."
"SuNyx has recently developed highly innovative products for use in the
field of proteomics with their MPep and MProtChip(R) technology, which
clearly addressed customer needs for cost-effective , convenient and reliable
sample preparation and analysis tools in the area of MALDI MS," added Michael
Lutz, Chief Executive Officer of SuNyx.

thermodynamic spectroscopic

TDA Research, Inc.
(NASDAQ: QGEN; Frankfurt, Prime Standard: QIA), the world's leading provider
of pre-analytical sample preparation products enabling genetic and protein
analysis, today announced that it has entered into a definitive agreement to
acquire the assets related to the bioanalytical business of SuNyx GmbH.

munir thermochemistry

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