Akira Endo of
Japanese for the "The Discovery of the Statins" in the prize category of "The
development of Novel Therapeutic Concepts and Technologies"
The two scientists will receive certificates of merit, and commemorative
medals.5, the standard among
interactive math software , enabling a wide range of professionals to
obtain the mathematically optimized solution to complex modeling
problems.D. is a provider of advanced medical image analysis
services.com.

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maplesoft.
(OTC Bulletin Board: VSCP), a leading developer of image-related biomarker
solutions, announced today that it has presented four co-authored papers at
the 52nd annual meeting of the Orthopaedic Research Society in Chicago, on
March 19-22, 2006.

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This opened the way to elucidating the three-dimensional temperature
structure of, and distribution of micro-components such as ozone in the
atmosphere across the entire globe.

VirtualScopics Presented Research Findings at 52nd Annual Meeting of the Orthopaedic Research Society

"This knowledge is leading us towards better understanding of disease in
its reversible stages, and increases our ability to assess the efficacy or
futility of experimental drugs and/or medical devices earlier in the clinical
trial process," said Bob Klimasewski, president and CEO of VirtualScopics.

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scientist, Sir John Houghton CBE FRS, for the "Pioneering
research on atmospheric structure and composition based on his satellite
observation technology and for promotion of international assessments of
climate change" in the prize category of "Global Change" and Dr.

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The Global
Optimization Toolbox is a very valuable resource for anyone who deals
with nonlinear optimization problems in operations research,
engineering, economics or other applied sciences., a system for
automated grading of mathematics tests., chief technical officer;
Larry Molinelli , IP+A manager; and Monica Barbu-McInnis, imaging scientist.com

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In addition,
Maplesoft leads the market with innovations that make the management
of technical knowledge - whether in industry , or in a classroom - more
effective and efficient.

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In business, constraints are related
to many factors, including cost, time and staff."
"The Global Optimization Toolbox has given me a new way to handle
the complex and difficult optimization problems in my operations
research projects, " said Professor Mahmut Parlar, chair, Management
Science/Information Systems, DeGroote School of Business, McMaster
University, Canada. "Maple is a cornerstone for my daily research and
to have an easy-to-use, Maple-based toolbox for projects such as
non-convex optimization and objective functions is ideal. Its standards-compliant algorithms are
renowned for its speed, accuracy and reliability . For more information, visit www., osteochondral defects and subchondral bone cysts).

CONTACT: Tracy Bagatelle-Black
Bagatelle-Black Public Relations
661/263-1842
tracy@bagatelleblack.

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Over two million users at thousands of
organizations benefit from advanced Maple technology." This canine study demonstrated the potential of MRI as a non-invasive
tool to accurately detect cartilage degradation associated with osteoarthritis
in early stages of the disease.
VirtualScopics, Inc.
VirtualScopics has created a suite of image analysis tools used in detecting
and analyzing specific structures in volumetric medical images, as well as
characterizing minute changes in structures over time, providing vital
information to support clinical trials and diagnostic applications.

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For more information about VirtualScopics, visit
http: //www.

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Designed to work seamlessly with the core Maple product suite, these
high-performance products deploy best-of-breed technology to deliver
maximum benefit from the world's most powerful technical software
platform. Factors that could cause or contribute to such differences
include, but are not limited to, those discussed from time to time in reports
filed by the Company with the Securities and Exchange Commission.

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Business Editors/High-Tech Editors

WATERLOO, Canada----Maplesoft (TM),
the leading provider of high-performance software tools for
engineering, science and mathematics , today announced the success of
its Global Optimization Toolbox in the academic, commercial and
research markets. Maplesoft products embody the
most advanced and integrated technology for both numeric and symbolic
solution of complex problems.virtualscopics. Investors are cautioned
that all forward -looking statements involve risks and uncertainties that could
cause actual results to differ materially from those in the forward-looking
statements.

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U.K. and Japanese Scientists Named as Laureates of the 2006(22nd) Japan Prize

OUTLINE
Observations by weather satellites began in the 1970s , when Sir John
Houghton developed a new means for making observations to measure the
temperatures and composition of the upper atmosphere based on his independent
theory.
This discovery triggered world-wide research into the compactin group and
resulted in the birth of several hypercholesteremia drugs from amongst that
group.
The first presentation was "Correlating Biochemical, Histologic , and MRI
Measures for Early Diagnosis of Osteoarthritis in the Pond-Nuki Model in
Dogs. The
firm 's proprietary software algorithms can assemble hundreds of separate
medical images taken during an MRI session into a single, three-dimensional
model, bringing a new and previously unobtainable source of data to clinical
researchers.

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The presentation ceremony is scheduled to
be held in Tokyo at the National Theatre on Thursday 20, April 2006

Laureates of the 2006(22nd) Japan Prize
Field I: Global Change
Sir John Houghton CBE FRS (United Kingdom)
Honorary Scientist , Hadley Centre for Climate Prediction and Research and
Formerly Chief Executive, Meteorological Office , UK
Date of Birth : December 30, 1931, 74 years
For pioneering research on atmospheric structure and composition based on
his satellite observation technology and for promotion of international
assessments of climate change. Frequently, engineers and
researchers are forced to settle for solutions that are "good enough"
at the expense of extra time, money, and resources, because the best
solution has not been found.
"The Global Optimization Toolbox meets the needs of industry
professionals by providing the tools they need to solve a wide range
of complex modeling problems , ranging from advanced engineering design
applications to econometrics and finance, management science , medical
research and biotechnology, and scientific modeling," said Dr.

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They are U.K.
Then he established the Hadley Centre for Climate Prediction and Research
to pursue this research and to study international climate change. Akira Endo isolated from penicillium a ground-breaking
substance called ML-236B (currently known as compactin) that lowers blood
cholesterol levels, and confirmed that it was also effective in humans.
Optimization is the science of finding solutions that satisfy
complicated constraints and objectives.

About Maplesoft

Maplesoft is a world leader in mathematical and analytical
software. The four studies are co-authored by Saara Totterman, M ., chief medical officer; Jose Tamez-Pena, PhD.
"This is important for our customers to more inexpensively , efficiently and
quickly bring a drug to market. The company evolved from research first carried out at the
University of Rochester Medical Center and School of Engineering.

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, VirtualScopics, Inc .,
Ph.e.

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Akira Endo (Japan)
Director, Biopharm Research Laboratories, Inc. These drugs, known collectively as statins, are presently used by
approximately thirty million people around the world and help to prevent
cardiac disease and stroke and so on. Laurent
Bernardin, Maplesoft's Chief Scientist.com/products/toolboxes or call
1-800-267-6583 ext 411 (US and Canada).

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He also
has played a central role in compiling the First, Second and Third Assessment
Reports under the auspices of the Intergovernmental Panel on Climate Change
(IPCC).

Field II: The Development of Novel Therapeutic Concepts and Technologies
Dr.

Maplesoft's Global Optimization Toolbox Penetrates Key Markets; Powerful Solution Brings Industrial-Class Optimization to Academic Commercial and Research App

"
The Global Optimization Toolbox is part of the Maple Professional
Toolbox series of add-on products that greatly extend the scope and
functionality of Maplesoft products in specialized application areas. MRI is particularly useful in allowing for
visualization of cartilage thickness, subchondral changes and measurement of
defects.
The last presentation, "Validation of MRI-Based Measures of Osteoarthritic
Cartilage Biomarkers by Direct Comparisons to Histological Sections,"
demonstrated the accuracy of MRI in detecting and measuring various biomarkers
(i.

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In engineering, constraints
may arise from technical issues.5, the standard among
interactive mathematical software; MapleNet , a comprehensive
mathematical infrastructure for the Web; and Maple T.maplesoft.
The third presentation was entitled, "Comparison of Arthroscopy and MRI
for Grading of Knee Chondromalacia ," and demonstrated that MRI can be useful
in supplementing arthroscopy and subjective scoring of the severity of
chondromalacia of the knee.

Forward-Looking Statements
The statements contained in this press release that are not purely
historical are forward-looking statements within the meaning of Section 27A of
the Securities Act of 1933, as amended and Section 21E of the Securities
Exchange Act of 1934, as amended, and are intended to be covered by the safe
harbors created thereby .

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, Tokyo, Japan
Date of Birth: November 14, 1933, 72 years
For the Discovery of the Statins and their Development
OUTLINE
In 1973 Dr. For more information,
visit http://www.A .

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"Using the Global Optimization
Toolbox, users can formulate optimization models easily inside the
powerful Maple numeric and symbolic system, and then use world-class
Maple numeric solvers to return the best answer, fast. Its suite of products includes Maple 9.com

Y."

About VirtualScopics, Inc.

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Released in June 2004, the Global Optimization
Toolbox extends the power of Maple(TM) 9.

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TOKYO, The Science and Technology Foundation of
Japan announced the names of two laureates for the 2006(22nd) Japan Prize
today. There is also a cash award of fifty million Japanese yen (Japanese Yen
50,000,000) for each prize category. In addition to US-based organizations such as Fairchild
Semiconductor, Kentucky State University and Los Alamos National
Laboratory, the Global Optimization Toolbox is being used by
organizations in Japan, Korea, Germany, Italy and France , among
others.
These research projects add to VirtualScopics' growing knowledge base of
modern imaging techniques such as magnetic resonance imaging (MRI) and
computed tomography (CT) to reduce the need for invasive techniques to assess
severity of disease, and to increase its understanding of structural and
functional manifestations of disease.

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The goal of global
optimization is to find the absolute best answer for models that have
a number of possible solutions, a process that can be extremely
difficult without the best tools.
Additionally, virtually every major university and research institute
in the world, including MIT, Stanford, Oxford and Waterloo, has
adopted Maple products to enhance their education and research
activities. ROCHESTER, N. This is significant because it opens up the
possibility of accurately assessing the disease at an early stage where it is
still reversible through medical intervention. Forward-looking statements deal with the Company 's
current plans, intentions, beliefs and expectations.

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"
"Maple's optimization add -on has permitted me to lock in on
optimal parameters in problems involving six parameters on a system
with three orders of magnitude for each dimension," said Ron Lenk,
systems applications engineering manager at Tyco Electronics and
author of Practical Design of Power Supplies.D.

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"Full global
optimization is critical and Maple's optimization add-on is the only
software I have tried that even comes close to solving these
problems. Toolboxes target key application areas in engineering,
science and technical application development. Maplesoft's
commercial customer base includes Boeing, Bosch, Canon and NASA.
The second presentation, "Acetabular Cup Migration Analysis from CT
Images," showed the ability of CT scans to detect the migration of hip
implants without prior knowledge of the implant design and without surgical
intervention.