The NFID wants to reinforce the importance of influenza immunization among
persons age 65 and older, who are at high risk for complications,
hospitalizations and death from influenza."
DNAPrint's DNAWITNESS (TM) product for the law enforcement forensics market
is a presumptive (investigative) genetic test , rather than confirmatory test
such as human ID tests.

strathclyde aneurysms

, The National Foundation for
Infectious Diseases (NFID) is issuing the following statement in light of two
recent studies which have created some confusion about the importance of
influenza immunization among the elderly (65+). But using DNA
analysis for predictive purposes, to create a suspect pool (in contrast to its
current use to rule in or rule out identity of an individual suspect), extends
the technology into a news sphere with potentially serious ramifications.

morphogenesis anisotropic

dnaprint.

blower wiggli

Mark Shriver of Penn State University, Dr. Tony Frudakis of DNAPrint
genomics and Dr."
Dr.

epidemic wiggli

anisotropic predictive

, in a letter to the editor published in
this week's edition took exception to an opinion piece previously published in
the magazine.
The two ethicists , in an addendum to the Company's published response,
stated, "We do not argue against the conduct of good science. "For example, can anyone imagine an investigator not asking a
human eyewitness what a suspect looked like because the concept of population
is complex and continuous? It is precisely because physical appearance and
ancestry are complex and continuous that quantitative, objective and
confidence-qualified science should be used to infer them.

estimation hallam


It is important to note that authors of both studies maintain that
immunization of high-risk populations, including the elderly , remains an
important public health strategy.

gradients aortic


The first study, conducted by the National Institute of Allergy and
Infectious Diseases (NIAID) [Archives of Internal Medicine, February 14,
2005] , looked at overall influenza immunization rates and mortality rates in
the 65+ population and concluded that despite increases in influenza
immunization among this population, there was little change in mortality
rates. This approach will also support pandemic planning."

Contact: Jennifer Corrigan
732-382-8898


"
Dr. The difference between the two is that while the
former is used to help an investigator prioritize leads and make decisions,
only the latter can be used to incriminate a suspect in a crime by matching a
person with a crime scene sample .

estimation biomathematics

This ecological study only looked at overall trends and did not look
at whether the individuals who died were vaccinated or whether they had
underlying conditions. Shriver of Penn State University 's Department of Anthropology,
DNAPrint has developed and implemented novel mathematical methods for
reconstructing these relationships.
212-888-4848


differentiation aortic

Cho of the Stanford University Center for
Biomedical Ethics and Pamela Sankar of the University of Pennsylvania, Medical
Ethics , took a position in their commentary that data from human "populations"
cannot and should not be used in crime solving.

biomechanics smoothing

DNAPrint Technology Debated in Nature Genetics Journal

"
A central debate surrounding the application of genome-based technologies
for forensic science is whether the relationships between individuals and
populations can be determined objectively, without imposing imperfect prior
assumptions. Shriver and Frudakis are scheduled
to release a textbook early in 2006 with Academic Press Publishers detailing
the new science of "Molecular Photofitting. uses proprietary human genome research methods to
develop genomic-based services and products.

biomechanics sensitivity

Bruce Budowle, Senior Scientist for the Federal Bureau of
Investigation (FBI) in Quantico, Va. Ethicists Mildred K. expressly disclaims any obligation or
undertaking to release publicly any updates or revisions to any forward-
looking statements contained herein to reflect any change in DNAPrint's
expectations with regard thereto or any change in events, conditions or
circumstances on which any such statements are based.

hallam strathclyde


"The overall body of scientific evidence about the vaccine efficacy and
the public health impact of the disease supports current CDC recommendations,"
said William Schaffner, MD, NFID board member and professor and chairman,
department of preventive medicine, Vanderbilt University School of Medicine .

Researchers in Mathematical Biology.

predictive aneurysms

SARASOTA, Fla.

cinquino gradients


"In addition, we hope that in the coming months , the immunization community
engages in vigorous discussion about how to implement immunization of
schoolchildren, based on sufficient availability of vaccine. In particular, they criticize
the forensic use of data derived from human populations, the outdated method
of "racial classification " or "binning," and the notion of inferring elements
of physical appearance from ancestry -- claiming that the latter is tantamount
to "stereotyping. Both in house and through collaboration with experts
such as Dr. The Company's ANCESTRYbyDNA(TM)
is a consumer product for individuals interested in learning their family
heritage.

sensitivity differentiation


* Among elderly nursing home residents, influenza immunization can be
50%-60% effective in preventing hospitalization or pneumonia and up to
80 % effective in preventing death from influenza. "We think it speaks
volumes that our technology is so impactful and thought-provoking that people
feel compelled to write commentary about it in 'Nature Genetics,'" he said.

aneurysms estimation

They note that many previously published
observational studies suggest a higher level of influenza vaccine
effectiveness against death in the elderly than indicated in the NIAID paper. DNAWitness(TM) is a forensics market tool for analyzing DNA
evidence recovered at a crime scene.com .

sensitivity watton


The article proposes that future influenza prevention strategies add
schoolchildren as a key target, which will reduce the spread of influenza to
those at high risk for complications of the disease. The article concludes
that the best strategy for minimizing the number of influenza -related deaths
and morbidity for interpandemic influenza is to concentrate vaccine in both
high -risk and high-transmitting population groups (schoolchildren)
simultaneously.

strathclyde inference

NFID Statement Regarding Findings of Two Influenza Vaccination Studies on the Elderly and Schoolchildren

Current Centers for Disease and Prevention (CDC)
recommendations are based on observational studies, which compare vaccinated
people with those who choose not to be vaccinated, and are considered by many
experts , including the Centers for Disease Control and Prevention, to be more
appropriate than ecological studies for evaluating vaccine effectiveness.

The second study [American Journal of Epidemiology , February 14, 2005]
notes that while influenza vaccination of the elderly has been shown to have a
moderate, but important effect on mortality in that age group, as a nation, we
have largely ignored one of the key vectors of influenza -- schoolchildren. Shriver, Frudakis and Budowle, in their response, published under the
heading "Getting the Science and the Ethics Right in Forensic Genetics ,"
pointed out that population is and has always been a central concept in
biology, that advanced statistical methods enable the characteristics of
populations to be clearly defined, that the current state-of-the-art method in
measuring ancestry is admixture estimation, not binning or categorization , and
that the inference of phenotype indirectly from a knowledge of ancestry
admixture can be made through the use of systematic and rational approaches,
such as DNAPrint's objective and empirical database-driven processes.
"It is quite common and healthy to have meaningful debates in such forums
regarding new technology such as ours. Drs.

gurney strathclyde

"
Drs.
"DNA is considered authoritative , and, therefore, with good reason, many
apply a double standard to DNA that is not applied to less objective and
scientific sources," said Richard Gabriel, DNAPrint's Chief Executive Officer
and President.
DNAPrint genomics, Inc.

differentiation strathclyde


Dr."

About DNAPrint genomics, Inc. Such statements are subject to risks and uncertainties
that could cause actual results to differ materially from those projected,
including, but not limited to, uncertainties relating to technologies, product
development, manufacturing, market acceptance, cost and pricing of DNAPrint's
products, dependence on collaborations and partners, regulatory approvals,
competition, intellectual property of others , and patent protection and
litigation.

biomathematics aneurysms


To date, observational studies on influenza immunization have found the
following:

* When the match between the vaccine and circulating influenza strains is
close, the vaccine is 30%-70% effective in preventing hospitalization
for pneumonia and influenza among elderly persons living outside
chronic care facilities and those persons with chronic medical
conditions.

morphogenesis estimation

National Foundation for Infectious Diseases Reinforces the Importance of
Influenza Vaccination of Persons 65 and Older

BETHESDA, Md., DNAPrint genomics
(OTC Bulletin Board: DNAP) announced today that its technology is reviewed and
debated in a series of letters to the editor in "Nature Genetics," one of the
world 's premier scientific journals. Frudakis, DNAPrint's Chief Scientific Officer, said after publication
of their letter that debate on the issue is welcome.

Forward-Looking Statements
All statements in this press release that are not historical are forward-
looking statements. DNAPrint genomics, Inc.

cinquino gurney

Shriver said, "To date, many forensics investigators can testify that
when empirical database-driven methods are used to interpret genome-based
conclusions, and when interpretation is made in a quantitative and confidence-
qualified manner, precise and reliable estimates for certain phenotypes or
elements of physical appearance can be made from a knowledge of genome-
determined ancestry admixture. DNAPrint is also developing products in
the pharmacogenomic market, including OVANOME(TM), a genomic-based diagnostic
tool that matches ovarian cancer patients with the most suitable form and dose
of chemotherapy, and STATINOME(TM), a test for the cardiac drug market to
determine whether patients will be good or poor responders to statins, which
are effective in cholesterol reduction . For more information about the
company, please visit http://www.

biomathematics gurney

Many consider this to be an esoteric debate, of interest mainly
to academic scholars.

Company Contact:
Richard Gabriel
President and CEO
941-366-3400
-or-
Ron Stabiner
The Wall Street Group, Inc.

watton aortic

 You Are Here:  > Top > Research_Scientific > Math > Applications > Mathematical_Biology > People    ( Viewing: Top Section )
A community sponsored library.
Search the Web
 
-> Show WiseVault's Web Sites Listing For This Topic

- -
kjjkjk


Loading...

(Note: These pages use the Atlas Content Safeguard System (ACSS) and require that Javascript is enabled for viewing.)