C. McConnell explained, "At Mayo, we have been using gel electrophoresis
to determine LDL particle size, since we developed and introduced the method
in 1999."
Brajer added, "We believe a preeminent institution such as Mayo Clinic
will generate additional independent clinical data further confirming the
clinical value of the NMR LipoProfile test.

subfields spectroscopy

This relationship is also
indicative of our future strategy of making LipoScience NMR technology a
widely available standard of care. develops and markets new clinical applications of
nuclear magnetic resonance (NMR ) spectroscopy in the areas of cardiovascular
disease and metabolic disorders. To learn
more about Mayo's Department of Laboratory Medicine and Pathology and Mayo
Medical Laboratories, visit http: //www.

radiocarbon properly

com), as a tool
to measure cardiovascular risks.
As part of its assessment, Mayo researchers will determine the value of
the NMR LipoProfile test independently and as a part of its Novel
Cardiovascular Risk Marker Panel, a group of emerging risk factors used to aid
physicians in assessments of their patients' risks for developing
cardiovascular disease or experiencing cardiovascular events, such as a heart
attack or stroke.

More About Liposcience and Lipoprotein Technology
Lipoprotein particles are tiny spheres that transport cholesterol
throughout the body.
Increased numbers of LDL particles indicate an increased risk of heart
disease, even if cholesterol levels are normal. MML is the reference laboratory for Mayo Clinic,
providing services to over 5,000 health care institutions worldwide.

radiocarbon methodology

properly stereology

Introduced in 1999 by LipoScience, the NMR LipoProfile(R) test is a simple
blood test used by physicians to directly measure the number of atherogenic
LDL particles (LDL-P) and VLDL particles, as well as protective HDL particles.
LipoScience, Inc.

resonance geomatics

Dr .
With the new cholesterol targets recently established by the National
Cholesterol Education Program (NCEP) for patients at moderate or high levels
of risk, the same principle remains true - an increased number of LDL
particles is the direct measure of CHD risk.
(Logo: http://www .

cryotechnology methods

, LipoScience, a privately-held
medical technology company, announced today that it has entered into a
collaborative agreement with Mayo Clinic, to validate the clinical utility of
LipoScience 's NMR LipoProfile(R) test (http://www. Evidence shows that measuring the numbers of "bad"
lipoprotein particles (LDL-P) in blood gives a much better indication than
"bad" cholesterol (LDL-C) measurements of the risk of developing coronary
heart disease (CHD).

stereology acoustics

Mayo Enters Agreement with LipoScience Inc .

lipoprofile. LipoScience's
vision is saving lives by establishing nuclear magnetic resonance diagnostics
as a clinical standard of care.4 million NMR LipoProfile
tests have been performed .

properly uncertainties

The level of risk is further
influenced by the size of the particles, with smaller LDL particles creating a
higher risk than larger ones.

synchrotrons radiocarbon

"If the findings are consistent with the published literature , we
will include this test as part of our novel cardiovascular risk panel, which
is offered to Mayo Clinic patients and to those served through our reference
laboratory, Mayo Medical Laboratories .
- Extensively illustrated throughout with over 200 figures, 400 tables,
and 3,000 references.

geoarchaeology microanalysis

"
LipoScience, a privately held medical technology company, provides
clinically superior diagnostic information to health care professionals using
proprietary magnetic resonance based products and services. DUBLIN, Ireland, Research and Markets
(http://www.com/reports/c18795

Laura Wood
Senior Manager
Research and Markets
press@researchandmarkets .

addressed expressing

Research and Markets: Coverage on the Reformulation of Polymeric Materials Zoning in on Non-Polymeric Components

researchandmarkets.

stereology uncertainty

(Photo: http://www.com/cgi-bin/prnh/20050803/CLW005 )
"We are very pleased to have the opportunity to be the first center to
clinically assess and validate this technology," said Dr."
Richard O.researchandmarkets.

geomatics uncertainty

It is well suited for patients who are being considered for or who are
currently on LDL-lowering therapy -- patients considered to be at moderate or
high risk for having a cardiovascular event.com/cgi-bin/prnh/20040820/RESEARCH )
This industrially relevant resource covers all established and emerging
analytical methods for the reformulation of polymeric materials, with emphasis
on the non-polymeric components.

subfields microscopy

About Mayo Clinic's Department of Laboratory Medicine and Pathology and
Mayo Medical Laboratories
The Department of Laboratory Medicine and Pathology at Mayo Clinic has an
active test development and implementation program.

Scope
- Each technique is evaluated on its technical and industrial merits.

methods microscopy

Founded in 1994, LipoScience markets and sells the NMR LipoProfile test to
physicians, other healthcare professionals, commercial diagnostic laboratories
and clinical research clients.

metrology cryotechnology

Joseph McConnell,
Director of the Cardiovascular Risk Assessment Section of the Biochemical
Genetics Laboratory within Mayo Clinic's Department of Laboratory Medicine and
Pathology .

microanalysis methods

newscom.
- Emphasis is on understanding (principles and characteristics) and
industrial applicability.

acoustics metrology

RALEIGH, N. LipoScience's
vision is saving lives by establishing nuclear magnetic resonance diagnostics
as a clinical standard of care. The LipoScience NMR technology is currently the only available method
to assess LDL particle number."
LipoScience, a privately held medical technology company, provides
clinically superior diagnostic information to health care professionals using
proprietary magnetic resonance based products and services.com/reports/c18795) has announced the addition
of Additives in Polymers to their offering.com
Fax: +353 1 4100 980

resonance methodology

Based on recent clinical studies, LDL particle number may be a more
important parameter than LDL size in assessing coronary artery disease and
events.mayoreferenceservices.

Methods and techniques that are useful in a broad range of scientific and engineering applications include statistical methods , analytical chemistry, crystallography, microscopy and microanalysis, geographic information systems , and electronic data acquisition.

nist geoarchaeology

Brajer, president and chief executive officer at LipoScience,
Inc .org

newscom.

microanalysis methodology

subfields radiocarbon

noted, "Mayo Clinic is widely recognized as a leader in assessing novel
technologies that have the potential to significantly impact medical decisions
and patient management. In addition , Mayo
evaluates promising technology developed elsewhere to determine usefulness in
Mayo Clinic 's practice and as part of Mayo Medical Laboratories' (MML)
offering to its clients.

Contents include the following:

1 INTRODUCTION
Additives
Plastics formulations
Economic impact of polymer additives
Analysis of plastics

2 DEFORMULATION PRINCIPLES
Polymer identification
Additive analysis of rubbers: "Best Practice"
Polymer extract analysis
In situ polymer/additive analysis
Class-specific polymer/additive analysis

3 SAMPLE PREPARATION PERSPECTIVES
Solvents
Extraction strategy
Conventional extraction technologies
High-pressure extraction methods
Sorbent extraction
Methodological comparison of extraction methods
Polymer/additive dissolution methods
Hydrolysis

4 SEPARATION TECHNIQUES
Analytical detectors
Gas chromatography
Supercritical fluid chromatography
Liquid chromatography techniques
Capillary electrophoretic techniques

5 POLYMER/ADDITIVE ANALYSIS: THE SPECTROSCOPIC ALTERNATIVE
Ultraviolet/visible spectrophotometry
Infrared spectroscopy
Luminescence spectroscopy
High-resolution nuclear magnetic resonance spectroscopy

6 ORGANIC MASS SPECTROMETRIC METHOD
Basic instrumentation
Ion sources
Mass analysers
Direct mass spectrometric polymer compound analysis
Ion mobility spectrometry

7 MULTIHYPHENATION AND MULTIDIMENSIONALITY IN POLYMER/ADDITIVE ANALYSIS
Precolumn hyphenation
Coupled sample preparation - spectroscopy/spectrometry
Postcolumn hyphenation
Multidimensional chromatography
Multidimensional spectroscopy

8 INORGANIC AND ELEMENTAL ANALYTICAL METHODS
Element analytical protocols
Sample destruction for classical elemental analysis
Analytical atomic spectrometry
X-ray spectrometry
Inorganic mass spectrometry
Radioanalytical and nuclear analytical methods
Electroanalytical techniques
Solid-state speciation analysis

9 DIRECT METHODS OF DEFORMULATION OF POLYMER/ADDITIVE DISSOLUTIONS
Chromatographic methods
Spectroscopic methods
Mass spectrometric method

10 A VISION FOR THE FUTURE
Trends in polymer technology
Trends in additive technology
Environmental, legislative and regulatory constraints
Analytical consequences
Epilogue

Appendix I List of Symbols
Appendix II Functionality of Common Additives
Appendix III Excerpt of Polymer Additive Database
Subject Index

For more information visit
http://www.

expressing acoustics

To date, more than 1.

accelerators methodology

Because many methods and techniques are themselves important fields or subfields of science addressed elsewhere in the Open Directory , this category contains numerous cross-links to other categories.