, a subsidiary of Bruker
BioSciences Corporation (Nasdaq: BRKR), together announced the launch of a
bench top version of their popular CRYSTAL FARM(TM) product for
high -throughput protein crystallization at the 2005 Pittsburgh Conference in
Orlando.
The Crystal Farm is a fully integrated web-based incubation and imaging
system used for protein crystallization screening and optimization. is a leader in drug discovery
collaborations.

Diamonds and relatives are on the peripheries of the crystallographer field of interest.

rapidly protein

Bruker Daltonics
is a leading developer and provider of innovative life science tools based on
mass spectrometry.----In a move to
deliver a step-change improvement in low-energy beam currents, Axcelis
Technologies, Inc., headquartered in Beverly,
Massachusetts, provides innovative, high-productivity solutions for
the semiconductor industry.

molecules lattice

, please visit the Company's website at
http://www. Additional information
about Ciphergen can be found at http://www.

protein neutron

Statements in this press release with respect to Discovery Partners or its
business or products that are not strictly historical are "forward-looking "
statements within the meaning of the Private Securities Litigation Reform Act
of 1995 and involve a high degree of risk and uncertainty., Ciphergen Biosystems,
Inc. The company's Internet
address is: www.

mixture electron

The product introduced here
will be exhibited at the Bruker booth #3176.

About Ciphergen
Ciphergen's Biosystems Division develops, manufactures and markets a
family of ProteinChip (R) Systems and services for clinical, research, and
process proteomics applications.
The technology is seen as the most promising method of extending
the viability of low energy implants, especially for the production of
advanced ultra shallow junction (USJ) and dual poly gate (DPG)
transistor structures. "ClusterIon technology is the perfect
complement to Axcelis' low energy implant superiority , and we are
eager to collaborate with them in delivering the technology on volume
production tools .

The Crystallography is a misleading term.

crystallographers crystallographic

DPI offers integrated services, products, and systems that
span the drug discovery continuum, including target characterization, targeted
and screening-library design and synthesis, high throughput and high content
screening, lead generation and optimization , gene expression analysis, and
protein crystallization.

employing mixture

For more information on Discovery Partners
International, Inc. The company is using ClusterIon(TM) source technology
from SemEquip, a manufacturer of ion sources and ion delivery systems
for the OEM implanter market.

How the basic structures of living, rapidly changing world are connected with something as static as crystals? If one want to know 3-D structures of biological molecules - one need to crystalize them, then to put them into the X-ray beam and to interpret the obtained diffraction pattern.

peripheries lattice

S. Rich, President and CEO of Ciphergen. Actual results may differ materially from those projected in
such forward-looking statements due to various factors, including ProteinChip
technology's ability to consistently and rapidly purify proteins, ProteinChip
technology's ability to successfully discover, validate and assay biomarkers
and patterns of biomarkers that are highly predictive and therefore meet with
customer acceptance as diagnostics , and our ability to protect and promote our
proprietary technologies.

crystallographic crystallographers

vrml protein

"
"The Crystal Farm product has become very popular in large,
high-throughput labs, where it produces better quality crystals , more quickly
than traditional manual crystallization techniques.

"
Using a range of ProteinChip array chromatographic surfaces and wash
conditions, scientists can quickly identify those combinations that optimize
target protein purification conditions.

obtained misleading

The bench top system combines capacity for up to 15,000 simultaneous
experimental conditions, with DPI's patent pending "Cool Flash " imaging
technology, and includes a web-browser based interface that controls all
system functions either locally or remotely, including priority-based image
scheduling, viewing and scoring. Discovery Partners
International is headquartered in San Diego, California and has operations in
the United States and Europe.

About Bruker Biosciences
Bruker Biosciences Corporation, headquartered in Billerica, Massachusetts,
is the publicly traded parent company of Bruker AXS Inc. Investors should consult Ciphergen's filings with
the Securities and Exchange Commission, including its Form 10-Q dated May 10,
2005, for further information regarding these and other risks of the Company's
business.com

Forward-Looking Statements

This press release includes certain statements , known as
"forward-looking statements," which express the current expectations
of Axcelis management .

crystallographic vrml

The Crystal Farm products have become a
market leader in protein crystallization and imaging for the drug discovery
and high throughput crystallography community.com

Any statements contained in this press release that do not describe
historical facts may constitute forward-looking statements as that term is
defined in the Private Securities Litigation Reform Act of 1995."
Axcelis has been exploring molecular source technology as a
potential candidate for extending low energy implant technology since
the late 1990s.

rapidly vrml

com. and Bruker Daltonics
Inc.bruker-biosciences. Any
forward -looking statements contained herein are based on current expectations,
but are subject to a number of risks and uncertainties. Scientists can then translate these
on-chip conditions into a column chromatography protocol for purifying the
protein at lab scale. This method greatly aids in providing rapid protein
sequencing as well as purification for protein-protein interaction studies,
crystallography or activity assays.
"We are very excited that the market leader in ion implant has
agreed to implement our source technology," added Brian Cohen, chief
executive officer for SemEquip.

lattice simplicity

Discovery Partners International Inc. and Bruker AXS Inc. Announce New Bench Top Protein Crystallization System

(Nasdaq: DPII) and Bruker AXS Inc. ProteinChip Systems enable protein
discovery, characterization, identification and assay development to provide
researchers with predictive, multi-marker assay capabilities and a better
understanding of biological function at the protein level. These risks and other
risk factors relating to Axcelis are described more fully in the most
recent Form 10-K filed by Axcelis and in other filings from time to
time with the Securities and Exchange Commission.

vrml obtained

Experimental results stored in a SQL
database can be easily mined for monitoring and optimizing crystallization
experiments.
Roger Durst, Vice President of R+D and Global Crystallography Business Manager
of Bruker AXS.

About Discovery Partners
Discovery Partners International, Inc.

Safe Harbor Statement
Note Regarding Forward-Looking Statements: For purposes of the Private
Securities Litigation Reform Act of 1995 (the "Act"), Ciphergen disclaims any
intent or obligation to update these forward-looking statements, and claims
the protection of the Safe Harbor for forward -looking statements contained in
the Act.

Axcelis Marks Another Low Energy Implant Advance with Cluster Boron Beams; New SemEquip source offers 18X boost in low energy productivity

misleading molecules

"The technological
leadership of the Crystal Farm, together with Bruker's expertise and marketing
presence in X-ray crystallography, has allowed the Crystal Farm to establish a
strong position in this dynamic new market. Ciphergen's
Diagnostics Division is dedicated to the discovery of protein biomarkers and
panels of biomarkers and their development into protein molecular diagnostic
tests that improve patient care; and to providing collaborative R+D services
through its Biomarker Discovery Center (R) laboratories for biomarker discovery
for new diagnostic tests as well as pharmacoproteomic services for improved
drug toxicology, efficacy and theranostic assays.

For simplicity alternative techniques of structural biology, for example NMR, neutron and electron crystallography are also included here.

atoms crystallographic

discoverypartners. Cluster boron molecules contain 18 boron atoms
and deliver the equivalent of an 18-fold increase in beam current at
ultra low energy.

Axcelis Technologies, Inc. Axcelis is dedicated to developing
enabling process applications through the design, manufacture and
complete life cycle support of ion implantation, rapid thermal
processing, and cleaning and curing systems .

Probably the better name would be the 'structural chemistry' or even the 'structural biology'.

diffraction vrml

The new CRYSTAL FARM CF-150 employs the same technology as the
CF-400 model in a smaller footprint.
"The strategic partnership between Discovery Partners and Bruker AXS has
allowed us to provide powerful crystallization and X-ray diffraction solutions
to the drug discovery and structural biology communities," said John Lillig,
CTO + Vice President of Discovery Partners International. The factors that
could cause actual future results to differ materially from current
expectations include , but are not limited to, risks and uncertainties relating
to Bruker Biosciences' reorganization strategies , integration risks, failure
of conditions, technological approaches, product development, market
acceptance, cost and pricing of Bruker Biosciences' products, changes in
governmental regulations , capital spending and government funding policies,
FDA and other regulatory approvals to the extent applicable, competition, the
intellectual property of others, patent protection and litigation. These and
other factors are identified and described in more detail in our filings with
the SEC , including, without limitation, our annual report on Form 10-K for the
year ended December 31, 2003 , our most recent quarterly reports on Form 10-Q
and our current reports on Form 8-K. (Nasdaq: CIPH ) announced today that the United States Patent and
Trademark Office has issued Ciphergen U.
"Axcelis is adopting cluster boron technology because it delivers
superior throughput at low energy compared with tradition source
technology, further extending Axcelis' unparalleled strength in
critical low energy implant applications," said Mark Namaroff,
Axcelis' senior vice president of marketing .axcelis.

crystallography symmation

DPI has actively contributed to dozens of drug
discovery collaborations, working on many of the most promising new biological
target areas for the biotech and pharmaceutical industries.

For more information, please visit
http://www. "Our
Biomarker Discovery Center(R) scientists as well as leading researchers in our
customer base have successfully used this process to purify and identify
protein biomarkers discovered and validated through our Pattern Track
process.com .

Business Editors/Technology Editors

BEVERLY, Mass.

simplicity peripheries

Ciphergen Announces Issuance of Patent for SELDI-TOF-MS Assisted Protein Purification

"Protein purification is a major bottleneck today in protein
identification," said William E. Examples of such forward-looking statements include statements
regarding the use of ProteinChip arrays to rapidly purify proteins for protein
identification , interaction studies, crystallography or activity assays as
well as statements regarding the diagnostic tests that Ciphergen Diagnostics
is developing. (NASDAQ: ACLS) today announced that it will
integrate cluster boron source technology on select implant platforms. Product manufacturing and delivery issues ,
customer order push-outs or cancellations and product performance
could cause actual results to differ materially from those currently
anticipated as expressed in this press release.

crystallographers protein

Pittcon 2005, the 56th Pittsburgh Conference and Exposition on Analytical
Chemistry and Applied Spectroscopy , is being held from February 27 through
March 4 in the Orange County Convention Center. Bruker AXS is a leading developer and provider of life science and
advanced materials research tools based on X-ray technology.ciphergen.

molecules vrml

We disclaim any intent or obligation to
update these forward-looking statements. Patent 6,881,586, directed to
methods of rapidly purifying proteins.

NOTE: Ciphergen, ProteinChip and Biomarker Discovery Center are
registered trademarks of Ciphergen Biosystems , Inc. Axcelis Technologies has
key product development centers in Beverly, Massachusetts, as well as
in Toyo, Japan through its joint venture, SEN.

vrml symmation

The methods involve using
ProteinChip(R) chromatographic arrays integrated with SELDI-TOF-MS detection
to rapidly identify "on-chip" conditions for purifying a protein for
applications including protein identification. "The technology also
rivals the productivity of alternative plasma immersion techniques
without introducing the process issues typically associated with
non-mass analyzed plasma immersion, such as energy and species
contamination, poor angle control and lack of tilt capability.

crystallographers iucr

SAN DIEGO, Discovery Partners
International, Inc. By
providing high-throughput protein crystallization automation, Crystal Farm
addresses the critical quest for high-speed structure-based drug discovery and
design. We are excited to
introduce the bench top model which will make this technology accessible for
innovative new applications in smaller-scale laboratories as well," said Dr. Discovery
Partners' actual results may differ materially from those projected in the
forward looking statements due to risks and uncertainties that exist in
Discovery Partners' operations, development efforts and business environment,
including risks relating to customer adoption of Discovery Partners products
(including Crystal Farm products), the ability of Discovery Partners and
Bruker AXS to achieve the goals of their strategic alliance, Discovery
Partners' ability to establish and maintain strategic alliances with third
parties, the trend toward consolidation of the pharmaceutical industry,
technological advances by competitors, and other risks and uncertainties more
fully described in Discovery Partners' annual report on Form 10-K for the year
ended December 31, 2003 as filed with the Securities and Exchange Commission
and Discovery Partners' other SEC reports ."

About Axcelis Technologies, Inc.

protein iucr

Complements Existing Patents Covering Ciphergen 's Pattern Track(TM) Biomarker
Discovery to Assay Process including Protein Identification

FREMONT, Calif.