"These latest assays are a direct result of the highly productive
two-year collaboration between Affymetrix and ParAllele. The company
has about 900 employees worldwide.com.

sdg multimethods

"IPA 3.com/trial .

All statements in this press release that are not historical are "forward-
looking statements" within the meaning of Section 21E of the Securities
Exchange Act as amended, including statements regarding Affymetrix'
"expectations," "beliefs, " "hopes," "intentions," "strategies" or the like.
Such statements are subject to risks and uncertainties that could cause actual
results to differ materially for Affymetrix from those projected, including ,
but not limited to the Company's expectation that its acquisition of ParAllele
will be completed in the third quarter of 2005, risks of the Company's ability
to achieve and sustain higher levels of revenue, higher gross margins, reduced
operating expenses, uncertainties relating to technological approaches,
manufacturing, product development (including uncertainties relating to
commercial and technological success of the MegAllele Assays discussed in this
press release), personnel retention , uncertainties related to cost and pricing
of Affymetrix products, dependence on collaborative partners , uncertainties
relating to sole source suppliers, uncertainties relating to FDA and other
regulatory approvals, competition, risks relating to intellectual property of
others and the uncertainties of patent protection and litigation.

multimethods qualitative

The company's products and services
utilize a unique approach that leverages novel biochemical processes rather
than complex instrumentation to discover and analyze minute variations in the
human genome. Affymetrix urges ParAllele's investors and shareholders to read
these documents when they become available and any other relevant documents
filed with the SEC because they will contain important information. In addition, documents filed
with the SEC by Affymetrix are available free of charge by contacting
Affymetrix, Inc.

emphasises correlation

1, a web-based
software application that enables biologists and bioinformaticians to
understand biological mechanisms , pathways and functions.D. Mapping
files now support Affymetrix GeneChip Human Mapping 10K, 100K and
500K Array Sets.
(Nasdaq: AFFX) and ParAllele BioScience Inc. Affymetrix
and ParAllele are also continuing to work together to develop a variety of
additional SNP panels targeted at specific diseases that will be available
later in 2005.

phenomenological correlation

Chief Technology Officer and Vice
President, Research for Ingenuity. MegAllele(TM) Assays and GeneChip(R) Technology Enable Customers to Genotype
Up to 10,000 Custom or Pre-defined SNPs

SANTA CLARA, Calif . Available as both a complete system and
an upgrade to existing systems, it features a four-color scanning capability,
peripheral instrumentation, software, computer hardware, reagent kits and
arrays for the full range of custom and application-specific genotyping
experiments.

Important Information for ParAllele Investors and Shareholders:
Affymetrix will file a registration statement on Form S-4 containing a
prospectus with the SEC in connection with its proposed acquisition of
ParAllele . Investors
and shareholders will be able to obtain these documents free of charge at the
website maintained by the SEC at http://www.

correlation interpretative

ingenuity.

About Ingenuity Systems(R)
Ingenuity enables researchers to model, analyze and understand complex
biological systems foundational to human health and disease. The acquisition is expected to close in the
third quarter of 2005.Affymetrix . For more information about ParAllele, please visit the
company's website at http://www.

qed neuendorf

"With the addition of new APIs, our
customers now have the flexibility to incorporate IPA into their internal
tools and thus optimize the workflow for understanding the biological
mechanisms, pathways and functions most relevant to their research.1 release include:

-- Application Programming Interfaces (APIs): Facilitate integration
with your application and IPA for optimized workflow . For more information about Ingenuity Pathways
Analysis 3.
To accelerate research on specific applications, scientists are now using
several available panels of pre-optimized SNPs, including whole-genome coding
SNP analysis, disease-related studies and common animal models. Headquartered in South San Francisco,
Calif.

multimethods winmax

The new release of
IPA 3."
Highlights of the Ingenuity Pathways Analysis 3.4 million biological findings.1, please email http://www.
http://www.
"The new GCS 3000 MegAllele System provides scientists with the freedom to
design virtually any experiment they want using either custom or off-the-shelf
assays," said Greg Yap, Vice President of DNA Products , Affymetrix.

naturalistic winmax

Headquartered in Santa Clara,
Calif., Affymetrix has subsidiaries in Europe and Asia in addition to
manufacturing facilities in Sacramento, Calif. The understanding of how subtle genetic variations contribute to
disease risk, prognosis and drug response will lead to new and more effective
drugs, predictive diagnosis, and the ability to better tailor therapies to
individual patients .

sdg naturalistic

New APIs and SNP Mapping Functionality Supports Integration
and Biomarker Research

REDWOOD CITY, Calif., Ingenuity Systems today
announced the launch of Ingenuity Pathways Analysis (IPA) 3.com.com., Affymetrix Inc. The GCS 3000 7G offers improved scanning
performance and support for the next-generation of high-density, high
information content arrays . Affymetrix expressly disclaims any
obligation or undertaking to release publicly any updates or revisions to any
forward-looking statements contained herein to reflect any change in
Affymetrix ' expectations with regard thereto or any change in events,
conditions, or circumstances on which any such statements are based.

pentti sdg

Co-developed during a two-year
collaboration between the two companies , the assay products work with
Affymetrix' industry standard GeneChip(R) Scanner (GCS) 3000 System with a
newly available MegAllele four-color capability, to easily and cost-
effectively genotype panels containing up to 10,000 custom or pre-defined
SNPs. These and
other risk factors are discussed in Affymetrix' Form 10-K for the year ended
December 31, 2004 and other SEC reports, including its Quarterly Reports on
Form 10-Q for subsequent quarterly periods.

neuendorf qualidata

Ingenuity was founded in 1998 and is headquartered in Redwood City, California
with offices in Germany, Switzerland, France, the United Kingdom, and Japan.

multimethods bobbi

Affymetrix technology is used by the world's top pharmaceutical,
diagnostic and biotechnology companies as well as leading academic, government
and not-for-profit research institutes .com.

About ParAllele BioScience:
ParAllele BioScience is accelerating healthcare breakthroughs by providing
comprehensive genetic discovery solutions to the life science research,
pharmaceutical and diagnostic sectors., ParAllele BioScience was founded by a team of leading researchers from
the Stanford Genome Technology Center and Uppsala University.

nud qualidata

Affymetrix and ParAllele Launch Industry's Most Comprehensive Product Line for Targeted Genotyping

By leveraging the highly multiplexed MegAllele assay, scientists are
able to generate more data per experiment at a more cost-effective rate. More than 1,200 systems have been
shipped around the world and more than 3,000 peer-reviewed papers have been
published using the technology.ParAllelebio.

qed garson

"
"By combining ParAllele's proprietary assay technology with Affymetrix'
existing family of genotyping and expression products, researchers will be
able to benefit from the broadest possible menu of market-leading products,"
said Elizabeth Krodel, Senior Vice President of Product Development of
ParAllele.

naturalistic winmax

"
The GCS 3000 MegAllele System runs the full range of Affymetrix'
genotyping and expression products., 3380 Central Expressway , Santa Clara, California 95051,
Attention: Investor Relations, phone: 408-731-5000.

theorical correlation

1 meets the need in the marketplace for a robust pathways product
that can be effortlessly integrated with proprietary and third party
applications," said Ramon Felciano, Ph."
"By integrating the Affymetrix Mapping 10k, 100k and 500k products with
Ingenuity Pathways Analysis, we are enabling researchers to comprehensively
investigate SNP information in the context of the biological mechanisms of a
particular disease ," stated Greg Yap, Vice President of DNA Products, at
Affymetrix. "Researchers can use this technology to analyze their expression
and genotyping experiments together in a single unified pathways view of the
underlying biology.

Trials of Ingenuity Pathways Analysis 3. As announced on May 31, Affymetrix has entered into a definitive
agreement to acquire ParAllele. and Bedford, Mass.

pentti emphasises

The highly flexible assays offer researchers the ability to focus on
specific regions of the genome more quickly and in greater detail than ever
before. To date, ParAllele has established research
collaborations with multiple large pharmaceutical companies and prestigious
academic and government institutions.

emphasises pentti

ingenuity. For more information about Affymetrix,
please visit the company's website at http://www.

multimethods pentti

-- Updated Content: Leverage the newly acquired, high quality expert
curated Ingenuity content containing 1.
In addition, Affymetrix today announced the latest upgrade to its industry
standard GCS 3000 System. Since then, Affymetrix
GeneChip(R) technology has become the industry standard in molecular biology
research.

nud commented

About Affymetrix:
Affymetrix scientists invented the world's first microarray in 1989 and
began selling the first commercial microarray in 1994.

kerlin pentti

Ingenuity Systems Launches New Product IPA 3.1 Delivering Expanded Functionality and Performance

ingenuity. The Ingenuity
products include pathways analysis software and knowledge bases for biologists
and bioinformaticians, and enterprise knowledge management infrastructure,
content and services for leading pharmaceutical and biotech companies.sec.

qualidata pentti

1 seamlessly integrates with 3rd party and customer applications through
dedicated APIs and supports Affymetrix GeneChip Human Mapping 10K , 100K and
500K Array Sets, thus greatly expanding the relevance of IPA to biomarker and
pharmacogenomic research efforts. The GCS 3000 MegAllele System includes 7G
capabilities. Affymetrix' patented photolithographic
manufacturing process provides the most information capacity available today
on an array, enabling researchers to use a whole-genome approach to analyze
the relationship between genetics and health . The company's
investors include Abingworth Management, Index Ventures, Mohr Davidow Ventures
and Versant Ventures.

elicit kerlin

-- Mapping Files for SNPs: Map Affymetrix SNP identifiers., today announced the recent
launch of a broad line of MegAllele(TM) assays for targeted single nucleotide
polymorphism (SNP) genotyping applications.gov.

bobbi qualidata

1 are being offered at
http://www. "Our
recent agreement to acquire ParAllele will help us better serve our customers
by accelerating the rate at which we deliver new products to market and
driving innovative assay development.

NOTE: Affymetrix, the Affymetrix logo, and GeneChip are registered
trademarks owned or used by Affymetrix Inc.

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