Cognitive neuroscientist Tony J. The abnormal structures occurred in and around the
posterior parietal lobe, toward the back of the brain."
The study in NeuroImage compared 18 children with the deletion to 18
healthy children., a co-author of
both studies and medical director of the 22q and You Clinic at Children's
Hospital.S.

Professor N. Based on more than 30 years of
neuroscience and cognitive research, Fast ForWord products help children,
adolescents, and adults build the cognitive skills critical for improving
reading and language skills.

neural methodological

New research sheds light on
this split in abilities by investigating how differences in brain structures
may influence how the mind works.
Dr.
"Studies in adults have shown that damage to the posterior parietal lobe
impairs a person's visual-spatial and numerical thinking," said Dr. Using MRI techniques, the research team used newer methods
to confirm previous findings of reductions in posterior brain volume and in
grey and white matter. "It's like having a fuzzy signal on your cell
phone - the phone is working, but the connections are defective.D.D. Prakash, Professor
and Coordinator of the University Grants Commission Innovative Programme on
Learning Disabilities. Barbara Calhoun

Dr. Calhoun will also be
involved in new research studies involving Indian student populations,
which are now getting under way in Mumbai and Kolkata.

For more information about Scientific Learning and its products, visit our
Web sites at www.

psychonomic methodological

Simon is now at the M. He recently published two studies of patients at The
Children's Hospital of Philadelphia with chromosome 22q11.2
deletion syndrome perform poorly in math skills compared to verbal skills.
The findings may have implications for other diseases as well., and Elaine Zackai,
M.
Its pediatric research program is among the largest in the country, ranking
second in National Institutes of Health funding.

She currently leads Scientific Learning's efforts on evidence-based
research studies, including the publication of several randomized
control-group studies examining the effect of Fast ForWord software on
various student populations worldwide.

consciousness neural

-- Abnormal Brain Structure Linked to Spatial, Numerical Thinking Problems
When Children Lack Part of Chromosome --

PHILADELPHIA, Certain genetic diseases affect
children's educational abilities in a distinctive pattern: impairing their
numerical abilities more than their verbal skills. By pinpointing specific sites in the brain associated with
impaired mental functions, scientists hope to eventually help children retrain
their brains to follow alternative pathways and work around their cognitive
weaknesses., of Children's Hospital.

His co-authors on the NeuroImage study were
Lijun Ding, Joel P.2 deletion
syndrome.

psicologica preprints

They found children with the
chromosome deletion performed more poorly on experiments designed to test
visual attention orienting, enumerating, and judging numerical magnitudes."
Chromosome 22q11. Dr. McDonald -McGinn, and Dr.
Scientific Learning Corp. These efforts have resulted in more
than 65 published reports on the impact of Fast ForWord on cognitive and
reading performance within low-performing student populations.

neurobiology psychonomic

Researchers at The Children's Hospital of Philadelphia, studying a common
chromosome disorder, have used high-tech imaging tools to identify abnormal
brain tissue associated with problems in perceiving spatial relationships and
thinking about numbers. P.

interchange neurobiology

In addition, by measuring how water diffuses in the
brain, it indicates the layout of nerve fibers and suggests how brain areas
are connected to each other.edu. Dr.

In addition to her workshop leadership in Mysore, Dr.

psychonomic interchange

In the Cortex study, the Children's Hospital team compared 12 children
with the syndrome to 15 healthy children.
"These findings strengthen the evidence for a similar relationship in
children.D.chop. (NASDAQ: SCIL)
recently co-sponsored a workshop at India's highly regarded University of
Mysore that explored recent research in the application of neuroscience to
learning issues and brain plasticity." Over 80
teachers, special educators, health professionals, and students attended
the presentation, which included a multimedia demonstration of Scientific
Learning's Fast ForWord products, an array of computer-based
interventions designed to build the cognitive skills necessary for
effective learning.

apa memory

The current work draws on cognitive neuroscience - an emerging scientific
field that investigates how the mind arises from the biology of the brain. MRI can provide images and compute volumes of
anatomical features.I. The
current research provides evidence toward an explanation of that gap in
cognitive abilities.G. Zackai, of Children's
Hospital; and James Gee, M.edu

"

About Dr.brainconnection.

consciousness psychonomic

2 deletion syndrome.

The Children 's Hospital of Philadelphia houses the 22q and You Center, the
largest program in the world specializing in chromosome 22q11. With sponsorship from the National
Institutes of Health, researches from Children 's Hospital produced a map of
chromosome 22 in 1995, and in 1999, collaborated with the Human Genome Project
in publishing the sequence of chromosome 22, the first human chromosome to be
sequenced under that Project. Without
question, the size, scope, and needs found throughout India make it an
extremely attractive market for Scientific Learning. The
efficacy of the products has been confirmed by independent researchers, by
evaluating the results of standardized achievement tests , and by Scientific
Learning's scientists.

underlying psychonomic

Children's Hospital is a world center for
research and treatment of the syndrome.C.D. Nataraj, Director of the All India Institute of Speech and
Hearing in Mysore, inaugurated the workshop by emphasizing the need for
such workshops that address learning disabilities, which may affect 10 to
30 percent of the Indian student population.com, or
call toll-free 888-452-7323.

preprints perception

Institute of the University of
California, Davis. Simon.2 deletion syndrome is one of the most common genetic
sources of developmental disability.2 deletion syndrome is growing , as improved heart care allows
many more children to survive the heart defects that commonly occur in the
condition," said clinical geneticist Elaine H. "Our findings represent early steps toward that goal. In the early 1980s, geneticists at Children's
Hospital were among the researchers that identified deletions in chromosome 22
as responsible for the syndrome, and later developed a diagnostic test for the
syndrome that is now used around the world.

underlying perception

N.
"Together, these studies strengthen our hypothesis that abnormalities in
the brain's parietal lobe are a critical factor in the visual -spatial and
numerical processing difficulties that we see in children with this syndrome,"
said Dr. "Chromosome
22q11. "It may turn out that all these
conditions have common changes to critical pathways in the brain.

Contact: John Ascenzi
Phone: (267) 426-6055
Ascenzi@email. For international information, e-mail Peter
Carabi at pcarabi@scilearn.

neuropsychology motivation

led the studies of children
with chromosome 22q11. In this disorder, a tiny portion of chromosome 22 is missing,
causing symptoms such as heart defects, cleft palate, abnormal immune
responses and cognitive impairments. Simon., C.

perception comprehension

All
three tasks relate to how the children mentally represent objects and the
spatial relationships among them. The multidisciplinary center provides care for children needing
specialists in medical genetics, cardiology, plastic surgery, immunology,
endocrinology and neurology. Through its longstanding commitment to
providing exceptional patient care, training new generations of pediatric
healthcare professionals and pioneering major research initiatives, Children's
Hospital has fostered many discoveries that have benefited children worldwide. Calhoun holds a bachelor's degree from Brown University and
a doctorate from a joint University of California , Berkeley / University of
California at San Francisco Bioengineering program with additional training
from the Johns Hopkins University.

psycholinguistics comprehension

Researchers have known for some time that children with chromosome 22q11. In addition, its unique
family-centered care and public service programs have brought the 430-bed
hospital recognition as a leading advocate for children and adolescents.

"Building local awareness of the profound role that neuroscience can play
in building the skills necessary for academic success is one of our core
objectives in establishing the Fast ForWord product line not only in India,
but throughout Asia," said Peter Carabi, Scientific Learning's Director of
International Market Development.

neuroscience neuropsychology

Simon, Ph.2 deletion syndrome, the most common genetic deletion
syndrome. Simon ., of the University of Pennsylvania.

PRESS RELEASE Scientific Learning Co-Sponsors Learning Disabilities Workshop in India

underlying interchange

In previous research, Dr.

psicologica memory

D.
"It may be that the basic problem lies in how parts of the brain are
connected," said Dr."
The National Institutes of Health and the Philadelphia Foundation provided
funding for both studies., Donna McDonald-McGinn, M.

The Children 's Hospital of Philadelphia was founded in 1855 as the
nation's first pediatric hospital.chop.

Dr.P. "Our initial Fast ForWord
implementations and partnerships in other areas of Asia, including
Singapore, Thailand, and Hong Kong, have gone extremely well.

About Scientific Learning Corporation

Scientific Learning produces the patented Fast ForWord family of
products, a series of computer -delivered reading intervention products that
complement reading instruction.

neurobiology comprehension

Understanding the links between brain structure and brain function may
offer clues to improving methods to help children with specific learning
disabilities. A complementary study, in the
March issue of NeuroImage , describes structural abnormalities in the brains of
children with the syndrome. But the researchers also found something new: changes
in the shape, size and position of the corpus callosum, a structure that
connects the brain's two hemispheres. Simon's co-authors on the Cortex study were
Carrie Bearden, Ph.

The event was held October 10 as part of the company's market-expansion
activities in Asia and was co-sponsored by the Department of Psychology at
the University of Mysore, with the cooperation of Dr. She has an extensive background in bioengineering and auditory
neuroscience and is the recipient of several awards, including the National
Research Service Award and the University of California Regent's
fellowship.

cognition empirical

Simon. Bish, Ms.

psicologica comprehension

"As we gain greater understanding of the details of how neural circuits
are connected for particular brain functions, we can design strategies for
therapies, because children's brains are more plastic than adult brains, and
more capable of reconfiguring tasks through alternative paths," added Dr. Calhoun is the Director of Research for Scientific Learning
Corporation.

The exercises align with the scientifically based reading -research
guidelines and the requirements of the No Child Left Behind Act.

formulation solving

One
important factor driving the field is the application of tools such as
magnetic resonance imaging (MRI) to yield more precise measurements of
structures in the living brain. Simon. "The population of children with
chromosome 22q11. Zackai, M.com.

solving neurobiology

Simon has argued
that such visual-spatial skills are a fundamental foundation to the later
learning of counting and mathematics.

lively solving

Linking Brain to Mind in a Common Genetic Disease

D.
One study, in the April 2005 issue of Cortex, measures impairments in the
children's visual-spatial and numerical skills.2 deletion syndrome is one of a number of conditions with a similar
pattern of visual-spatial and numerical impairments, grouped as nonverbal
learning disabilities ," said Dr. For
more information, visit http://www. Barbara Calhoun, Scientific Learning's Director of Research, presented
the one-day seminar, entitled "Using Neuroscience-based Interventions to
Address Learning Disabilities that Inhibit Academic Success.