and Caroline M. Johnson Professor in the School of Engineering .

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The broad expertise of SRI's
interdisciplinary research team -- coupled with SRI's powerful Pathway
Logic tools for studying biological and biochemical change -- can
greatly aid in understanding human disease processes such as cancer
development.

About SRI International

Silicon Valley-based SRI International (http://www.sri.stanford.

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Pathway Logic(TM)
software, founded on the computational science of formal methods,
allows a rich set of logical operators to define relationships among
the components of complex biological systems.----Stanford
University's Institute for Computational and Mathematical Engineering
(ICME) is offering the degree of master of science in computational
and mathematical engineering (CME) to industry students completely at
a distance beginning in autumn 2005.

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Potential
biological mechanisms, such as susceptibility or resistance to
therapeutic intervention, can be experimentally tested using
hypotheses created by a model or by querying the model itself.

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Such model structures provide a way to organize diverse
information concerning biological and biochemical states and
processes, creating models that show how the systems evolve from a
starting state.
"Pathway Logic software, the core of the 'system' that will be
used for this important project, is a computational approach designed
to automatically generate and display complex networks of components
such as biological molecules and their interactions," said Keith
Laderoute, Ph. "To do mathematics and
mathematical applications requires the breadth and strength of a
top-rated university like Stanford," Moin says.

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sri."
ICME faculty members have joint appointments with other
departments in the School of Engineering.
Deadlines for applications to the CME MS program are March 1st for
autumn admission, July 31st for winter, and October 31st for spring.

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For this project , SRI will apply Pathway Logic(TM) software, SRI's
approach to modeling biological entities and processes based on the
Maude computer language (http://maude.com).

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The structure of a model can be altered on demand
according to user-specified conditions, and is easily modified to
accommodate new information and respond to queries. "Pathway
Logic software permits researchers to pose logical questions about
large biological networks -- which are actually formal models derived
entirely from experimental findings.

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Business Editors/High-Tech Writers/Health/Medical Writers
BIOWIRE2K

MENLO PARK, Calif.csl. In addition to conducting contract R+D, SRI
licenses its technologies, forms strategic partnerships and creates
spin-off companies.

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A system modeled by
Pathway Logic(TM) software offers compelling advantages for
understanding biological processes such as signal transduction and
metabolism at a global level.

About SRI International's Biosciences Division

SRI's Biosciences Division
(http://www. It includes new courses specifically developed for the graduate
program, as well as an expanding selection of electives that draw from
all these areas of research.

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D.

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com) is one
of the world's leading independent research and technology development
organizations.
"Computing now forms the third leg of a stool for scientific
discovery, allowing the performance and behavior of physical systems
to be predicted and studied.

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sri. Founded as Stanford Research Institute in 1946 , SRI has
been meeting the strategic needs of clients for almost 60 years.

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The Stanford Center for
Professional Development will deliver courses online worldwide and via
television broadcast within the San Francisco Bay Area. Stanford researchers
currently use computer simulation tools to explore a broad range of
real-world challenges, including: more efficient jet engines, surgical
strategies with better outcomes, improved understanding of protein
folding in health and disease, and optimized Internet traffic.

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About SRI International Computer Science Laboratory

The Computer Science Laboratory http://www.

Stanford University Announces Online MS in Computational and Mathematical Engineering; Interdisciplinary Degree Explores Newest Research Methodology

Business Editors/Education Editors

STANFORD, Calif. Advancements in super-computing have led
to the development of sophisticated multi-scale simulation tools,
increasing the need for computational engineers in almost every
industry .
Industry students may pursue degrees on a part-time basis while
continuing employment.

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, director of SRI's Cancer Biology Program."
SRI's Biosciences Division and Computer Science Laboratory will
co-develop the Pathway Logic model of cellular networks. The
nonprofit research institute performs contract research and
development for government agencies, commercial businesses and
nonprofit foundations.

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The Stanford Center for Professional Development offers graduate
degrees, credit courses, certificates and professional development
short courses to meet the career-long learning needs of engineers,
scientists, technology professionals and managers.
http://scpd.

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Admissions to the program and graduation
requirements are the same for distance learners and fulltime students .

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"Originally, scientists' research methodologies were theory and
experiment," explains Parviz Moin, ICME Director and the Franklin P.

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csl. Current systems of
interest include not only traditional computer hardware and software,
but also biological systems and nanoelectronics.

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SRI will be a subcontractor to LBNL and will develop a model of
cellular signaling networks related to human breast cancer.sri .

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----

SRI's Systems-Based Pathway Logic Software
Helps Predict Response to Cancer Therapies

SRI International, an independent nonprofit research and
development organization, today announced a grant from the National
Cancer Institute (a unit of the National Institutes of Health) and the
Lawrence Berkeley National Laboratory (LBNL) for the study of
signaling systems in biological networks associated with cancer cell
lines.com/biosciences/indexN. The division specializes in cancer,
infectious disease and neurobiological research. All courses
are taught by Stanford faculty and posted online within two hours of
live delivery.

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html) works with government
agencies and commercial pharmaceutical/biotech companies to provide a
broad range of preclinical drug discovery and development services,
including medicinal chemistry, custom synthesis, regulatory support,
efficacy and safety evaluations, pharmacokinetics and metabolism
studies, analytical chemistry and formulation design in production in
GLP and cGMP environments.edu/content?cme

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SRI International's Pathway Logic Tools Model Cellular Networks for Breast Cancer Research

com in SRI's
Information and Computing Sciences Division studies the logical
foundation of scalable systems that are beyond the scope of
traditional testing or simulation, and builds and applies efficient
high-level tools for rigorous mechanical analysis.
The CME master's degree curriculum reflects this interdisciplinary
focus.

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Twenty-three
Stanford master of science degree concentrations are available online
in: biomedical informatics, computer science, computational
mathematics and engineering , electrical engineering, management
science and engineering, and mechanical engineering.

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